Genes and Mechanisms Involved in the Generation and Amplification of Basal Radial Glial Cells

Derepression of sonic hedgehog signaling upon Gpr161 deletion unravels forebrain and ventricular abnormalities

(2019) Issei S. Shimada et al.   DEVELOPMENTAL BIOLOGY

Establishing Cerebral Organoids as Models of Human-Specific Brain Evolution

(2019) Alex A. Pollen et al.   CELL

RBM15 Modulates the Function of Chromatin Remodeling Factor BAF155 Through RNA Methylation in Developing Cortex

(2019) Yuanbin Xie et al.   MOLECULAR NEUROBIOLOGY

LIFR promotes tumor angiogenesis by up-regulating IL-8 levels in colorectal cancer

(2018) Hao-xuan Wu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Cortical organoids: why all this hype?

(2018) Fabio Marsoner et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Eyeless/Pax6 initiates eye formation non-autonomously from the peripodial epithelium

(2018) Luke R. Baker et al.   DEVELOPMENT

Cortical progenitor biology: key features mediating proliferation versus differentiation

(2018) Ana Uzquiano et al.   JOURNAL OF NEUROCHEMISTRY

The PDGF/PDGFR pathway as a drug target

(2018) Natalia Papadopoulos et al.   MOLECULAR ASPECTS OF MEDICINE

Aspm knockout ferret reveals an evolutionary mechanism governing cerebral cortical size

(2018) Matthew B. Johnson et al.   NATURE

Human brain organoids on a chip reveal the physics of folding

(2018) Eyal Karzbrun et al.   Nature Physics

Insm1 Induces Neural Progenitor Delamination in Developing Neocortex via Downregulation of the Adherens Junction Belt-Specific Protein Plekha7

(2018) Stefania Tavano et al.   NEURON

Genetics and mechanisms leading to human cortical malformations

(2018) Delfina M. Romero et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

A novel population of Hopx-dependent basal radial glial cells in the developing mouse neocortex

(2018) Samir Vaid et al.   DEVELOPMENT

Extracellular Matrix Components HAPLN1, Lumican, and Collagen I Cause Hyaluronic Acid-Dependent Folding of the Developing Human Neocortex

(2018) Katherine R. Long et al.   NEURON

Bridging the Gap between Mechanics and Genetics in Cortical Folding: ECM as a Major Driving Force

(2018) Florence Wianny et al.   NEURON

Expanding the Spectrum of BAF-Related Disorders: De Novo Variants in SMARCC2 Cause a Syndrome with Intellectual Disability and Developmental Delay

(2018) Keren Machol et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Epithelial-mesenchymal transition (EMT): A biological process in the development, stem cell differentiation, and tumorigenesis

(2017) Tong Chen et al.   JOURNAL OF CELLULAR PHYSIOLOGY

AP-1 Transcription Factors and the BAF Complex Mediate Signal-Dependent Enhancer Selection

(2017) Thomas Vierbuchen et al.   MOLECULAR CELL

Fused cerebral organoids model interactions between brain regions

(2017) Joshua A Bagley et al.   NATURE METHODS

The use of brain organoids to investigate neural development and disease

(2017) Elizabeth Di Lullo et al.   NATURE REVIEWS NEUROSCIENCE

Spatiotemporal gene expression trajectories reveal developmental hierarchies of the human cortex

(2017) Tomasz J. Nowakowski et al.   SCIENCE

The SWI/SNF chromatin remodelling complex is required for maintenance of lineage specific enhancers

(2017) Burak H. Alver et al.   Nature Communications

Self-Organized Cerebral Organoids with Human-Specific Features Predict Effective Drugs to Combat Zika Virus Infection

(2017) Momoko Watanabe et al.   Cell Reports

Gyrification of the cerebral cortex requires FGF signaling in the mammalian brain

(2017) Naoyuki Matsumoto et al.   eLife

Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia

(2017) Xin Heng et al.   eLife

Combined deletion and DNA methylation result in silencing of FAM107A gene in laryngeal tumors

(2017) Katarzyna Kiwerska et al.   Scientific Reports

Malformations of cortical development

(2016) Rahul S. Desikan et al.   ANNALS OF NEUROLOGY

Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure

(2016) Xuyu Qian et al.   CELL

Epigenetic regulation by BAF (mSWI/SNF) chromatin remodeling complexes is indispensable for embryonic development

(2016) Huong Nguyen et al.   CELL CYCLE

Brg1 directly regulates Olig2 transcription and is required for oligodendrocyte progenitor cell specification

(2016) Steven Matsumoto et al.   DEVELOPMENTAL BIOLOGY

Regulation of mitotic spindle orientation: an integrated view

(2016) Florencia di Pietro et al.   EMBO REPORTS

Brain Development and Akt Signaling: the Crossroads of Signaling Pathway and Neurodevelopmental Diseases

(2016) Long Wang et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Ablation of BAF170 in Developing and Postnatal Dentate Gyrus Affects Neural Stem Cell Proliferation, Differentiation, and Learning

(2016) Tran Tuoc et al.   MOLECULAR NEUROBIOLOGY

Hedgehog signaling promotes basal progenitor expansion and the growth and folding of the neocortex

(2016) Lei Wang et al.   NATURE NEUROSCIENCE

On the growth and form of cortical convolutions

(2016) Tuomas Tallinen et al.   Nature Physics

Post-transcriptional gene regulation by mRNA modifications

(2016) Boxuan Simen Zhao et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

From migration to settlement: the pathways, migration modes and dynamics of neurons in the developing brain

(2016) Yumiko HATANAKA et al.   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

A restricted period for formation of outer subventricular zone defined by Cdh1 and Trnp1 levels

(2016) Maria Ángeles Martínez-Martínez et al.   Nature Communications

HOPX functions as a tumour suppressor in head and neck cancer

(2016) Lee Fah Yap et al.   Scientific Reports

The Many Roles of BAF (mSWI/SNF) and PBAF Complexes in Cancer

(2016) Courtney Hodges et al.   Cold Spring Harbor Perspectives in Medicine

The hominoid-specific gene TBC1D3 promotes generation of basal neural progenitors and induces cortical folding in mice

(2016) Xiang-Chun Ju et al.   eLife

A single splice site mutation in human-specific ARHGAP11B causes basal progenitor amplification

(2016) M. Florio et al.   Science Advances

Signal Transduction Pathways of EMT Induced by TGF-β, SHH, and WNT and Their Crosstalks

(2016) Jingyu Zhang et al.   Journal of Clinical Medicine

PI3K/AKT pathway mutations cause a spectrum of brain malformations from megalencephaly to focal cortical dysplasia

(2015) Laura A. Jansen et al.   BRAIN

Molecular Identity of Human Outer Radial Glia during Cortical Development

(2015) Alex A. Pollen et al.   CELL

Brain oxygen tension controls the expansion of outer subventricular zone-like basal progenitors in the developing mouse brain

(2015) L. Wagenfuhr et al.   DEVELOPMENT

Coevolution of radial glial cells and the cerebral cortex

(2015) Camino De Juan Romero et al.   GLIA

Signaling pathway of MAPK/ERK in cell proliferation, differentiation, migration, senescence and apoptosis

(2015) Yu Sun et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Fixed single-cell transcriptomic characterization of human radial glial diversity

(2015) Elliot R Thomsen et al.   NATURE METHODS

Single-cell analysis reveals transcriptional heterogeneity of neural progenitors in human cortex

(2015) Matthew B Johnson et al.   NATURE NEUROSCIENCE

The Protein Tyrosine Phosphatase Rptpζ Suppresses Osteosarcoma Development in Trp53-Heterozygous Mice

(2015) Christina Baldauf et al.   PLoS One

Human cerebral organoids recapitulate gene expression programs of fetal neocortex development

(2015) J. Gray Camp et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion

(2015) M. Florio et al.   SCIENCE

Regulation of cerebral cortical neurogenesis by the Pax6 transcription factor

(2015) Martine N. Manuel et al.   Frontiers in Cellular Neuroscience

Morphological and functional aspects of progenitors perturbed in cortical malformations

(2015) Sara Bizzotto et al.   Frontiers in Cellular Neuroscience

Cell Division Modes and Cleavage Planes of Neural Progenitors during Mammalian Cortical Development

(2015) Fumio Matsuzaki et al.   Cold Spring Harbor Perspectives in Biology

N-cadherin-based adherens junction regulates the maintenance, proliferation, and differentiation of neural progenitor cells during development

(2015) Yasunori Miyamoto et al.   Cell Adhesion & Migration

Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development

(2015) Ramanathan Narayanan et al.   Cell Reports

Sustained Pax6 Expression Generates Primate-like Basal Radial Glia in Developing Mouse Neocortex

(2015) Fong Kuan Wong et al.   PLOS BIOLOGY

The role of BAF (mSWI/SNF) complexes in mammalian neural development

(2014) Esther Y. Son et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

Role of radial glial cells in cerebral cortex folding

(2014) Víctor Borrell et al.   CURRENT OPINION IN NEUROBIOLOGY

Shp2-Dependent ERK Signaling Is Essential for Induction of Bergmann Glia and Foliation of the Cerebellum

(2014) Kairong Li et al.   JOURNAL OF NEUROSCIENCE

HIF1α Regulates mTOR Signaling and Viability of Prostate Cancer Stem Cells

(2014) Maximilian Marhold et al.   MOLECULAR CANCER RESEARCH

Radial glia require PDGFD–PDGFRβ signalling in human but not mouse neocortex

(2014) Jan H. Lui et al.   NATURE

Low-coverage single-cell mRNA sequencing reveals cellular heterogeneity and activated signaling pathways in developing cerebral cortex

(2014) Alex A Pollen et al.   NATURE BIOTECHNOLOGY

Mutations in Eml1 lead to ectopic progenitors and neuronal heterotopia in mouse and human

(2014) Michel Kielar et al.   NATURE NEUROSCIENCE

How does Reelin control neuronal migration and layer formation in the developing mammalian neocortex?

(2014) Katsutoshi Sekine et al.   NEUROSCIENCE RESEARCH

Gyrification from constrained cortical expansion

(2014) T. Tallinen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cajal, Retzius, and Cajal–Retzius cells

(2014) Verónica Martínez-Cerdeño et al.   Frontiers in Neuroanatomy

Control of Outer Radial Glial Stem Cell Mitosis in the Human Brain

(2014) Bridget E.L. Ostrem et al.   Cell Reports

The PTEN/PI3K/AKT Pathway in vivo, Cancer Mouse Models

(2014) Amancio Carnero et al.   Frontiers in Oncology

Disruption of Aspm causes microcephaly with abnormal neuronal differentiation

(2013) Akira Fujimori et al.   BRAIN & DEVELOPMENT

Trnp1 Regulates Expansion and Folding of the Mammalian Cerebral Cortex by Control of Radial Glial Fate

(2013) Ronny Stahl et al.   CELL

BAF chromatin remodeling complex: Cortical size regulation and beyond

(2013) Tran Cong Tuoc et al.   CELL CYCLE

Chromatin Regulation by BAF170 Controls Cerebral Cortical Size and Thickness

(2013) Tran Cong Tuoc et al.   DEVELOPMENTAL CELL

Regulation of cerebral cortex size and folding by expansion of basal progenitors

(2013) Miki Nonaka-Kinoshita et al.   EMBO JOURNAL

Conical expansion of the outer subventricular zone and the role of neocortical folding in evolution and development

(2013) Eric Lewitus et al.   Frontiers in Human Neuroscience

Cerebral organoids model human brain development and microcephaly

(2013) Madeline A. Lancaster et al.   NATURE

Precursor Diversity and Complexity of Lineage Relationships in the Outer Subventricular Zone of the Primate

(2013) Marion Betizeau et al.   NEURON

Pax6 Interactions with Chromatin and Identification of Its Novel Direct Target Genes in Lens and Forebrain

(2013) Qing Xie et al.   PLoS One

Self-organization of axial polarity, inside-out layer pattern, and species-specific progenitor dynamics in human ES cell-derived neocortex

(2013) T. Kadoshima et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitotic spindle orientation predicts outer radial glial cell generation in human neocortex

(2013) Bridget E. LaMonica et al.   Nature Communications

Spindle orientation in mammalian cerebral cortical development

(2012) Madeline A Lancaster et al.   CURRENT OPINION IN NEUROBIOLOGY

Comparative Analysis of the Subventricular Zone in Rat, Ferret and Macaque: Evidence for an Outer Subventricular Zone in Rodents

(2012) Verónica Martínez-Cerdeño et al.   PLoS One

Transcriptomes of germinal zones of human and mouse fetal neocortex suggest a role of extracellular matrix in progenitor self-renewal

(2012) S. A. Fietz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In vivo genetic manipulation of cortical progenitors in gyrencephalic carnivores using in utero electroporation

(2012) H. Kawasaki et al.   Biology Open

Development and Evolution of the Human Neocortex

(2011) Jan H. Lui et al.   CELL

The (Not Necessarily) Convoluted Role of Basal Radial Glia in Cortical Neurogenesis

(2011) R. F. Hevner et al.   CEREBRAL CORTEX

Abundant Occurrence of Basal Radial Glia in the Subventricular Zone of Embryonic Neocortex of a Lissencephalic Primate, the Common Marmoset Callithrix jacchus

(2011) Iva Kelava et al.   CEREBRAL CORTEX

Oblique Radial Glial Divisions in the Developing Mouse Neocortex Induce Self-Renewing Progenitors outside the Germinal Zone That Resemble Primate Outer Subventricular Zone Progenitors

(2011) A. Shitamukai et al.   JOURNAL OF NEUROSCIENCE

A new subtype of progenitor cell in the mouse embryonic neocortex

(2011) Xiaoqun Wang et al.   NATURE NEUROSCIENCE

Pax6 Is a Human Neuroectoderm Cell Fate Determinant

(2010) Xiaoqing Zhang et al.   Cell Stem Cell

A Role for Intermediate Radial Glia in the Tangential Expansion of the Mammalian Cerebral Cortex

(2010) Isabel Reillo et al.   CEREBRAL CORTEX

Neurogenic radial glia in the outer subventricular zone of human neocortex

(2010) David V. Hansen et al.   NATURE

OSVZ progenitors of human and ferret neocortex are epithelial-like and expand by integrin signaling

(2010) Simone A Fietz et al.   NATURE NEUROSCIENCE

Neural Progenitor Nuclei IN Motion

(2010) Elena Taverna et al.   NEURON

Mutations in mouse Aspm (abnormal spindle-like microcephaly associated) cause not only microcephaly but also major defects in the germline

(2010) J. N. Pulvers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integrins

(2009) Malgorzata Barczyk et al.   CELL AND TISSUE RESEARCH

Regulation of Radial Glial Survival by Signals from the Meninges

(2009) R. Radakovits et al.   JOURNAL OF NEUROSCIENCE

β1 Integrin Maintains Integrity of the Embryonic Neocortical Stem Cell Niche

(2009) Karine Loulier et al.   PLOS BIOLOGY

Neuroepithelial Stem Cell Proliferation Requires LIS1 for Precise Spindle Orientation and Symmetric Division

(2008) Jessica Yingling et al.   CELL

Distinct behaviors of neural stem and progenitor cells underlie cortical neurogenesis

(2008) Stephen C. Noctor et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Development of the human cerebral cortex: Boulder Committee revisited

(2008) Irina Bystron et al.   NATURE REVIEWS NEUROSCIENCE

Insulinoma-Associated 1 Has a Panneurogenic Role and Promotes the Generation and Expansion of Basal Progenitors in the Developing Mouse Neocortex

(2008) Lilla M. Farkas et al.   NEURON

A Sox1 to Pax6 Switch Drives Neuroectoderm to Radial Glia Progression During Differentiation of Mouse Embryonic Stem Cells

(2008) David M. Suter et al.   STEM CELLS