Allyl isothiocyanate ameliorates lipid accumulation and inflammation in nonalcoholic fatty liver disease via the Sirt1/AMPK and NF-κB signaling pathways

Zinc oxide nanoparticles attenuate hepatic steatosis development in high-fat-diet fed mice through activated AMPK signaling axis

(2019) Surbhi Dogra et al.   Nanomedicine-Nanotechnology Biology and Medicine

Current and future therapeutic regimens for nonalcoholic fatty liver disease and nonalcoholic steatohepatitis

(2018) Zobair M. Younossi et al.   HEPATOLOGY

Prediction of carotid intima-media thickness in obese patients with low prevalence of comorbidities by serum copper bioavailability

(2018) Giovanni Tarantino et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Fisetin Protects Against Hepatic Steatosis Through Regulation of the Sirt1/AMPK and Fatty Acid β-Oxidation Signaling Pathway in High-Fat Diet-Induced Obese Mice

(2018) Chian-Jiun Liou et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Sirtuin 3 acts as a negative regulator of autophagy dictating hepatocyte susceptibility to lipotoxicity

(2017) Songtao Li et al.   HEPATOLOGY

SREBP-regulated lipid metabolism: convergent physiology — divergent pathophysiology

(2017) Hitoshi Shimano et al.   Nature Reviews Endocrinology

AMPK: guardian of metabolism and mitochondrial homeostasis

(2017) Sébastien Herzig et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Sulforaphane prevents rat cardiomyocytes from hypoxia/reoxygenation injury in vitro via activating SIRT1 and subsequently inhibiting ER stress

(2016) Yun-peng Li et al.   ACTA PHARMACOLOGICA SINICA

Allyl isothiocyanate suppresses the proteolytic activation of sterol regulatory element-binding proteins andde novofatty acid and cholesterol synthesis

(2016) Shingo Miyata et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Persistent Nonalcoholic Fatty Liver Disease Increases Risk for Carotid Atherosclerosis

(2016) Dong Hyun Sinn et al.   GASTROENTEROLOGY

Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes

(2016) Zobair M. Younossi et al.   HEPATOLOGY

Hepatocyte TRAF3 promotes liver steatosis and systemic insulin resistance through targeting TAK1-dependent signalling

(2016) Pi-Xiao Wang et al.   Nature Communications

Pharmacokinetics, Tissue Distribution, and Anti-Lipogenic/Adipogenic Effects of Allyl-Isothiocyanate Metabolites

(2015) Yang-Ji Kim et al.   PLoS One

Allyl isothiocyanate ameliorates insulin resistance through the regulation of mitochondrial function

(2014) Jiyun Ahn et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Association of Non-alcoholic Fatty Liver Disease with Chronic Kidney Disease: A Systematic Review and Meta-analysis

(2014) Giovanni Musso et al.   PLOS MEDICINE

Hepatic SIRT1 Attenuates Hepatic Steatosis and Controls Energy Balance in Mice by Inducing Fibroblast Growth Factor 21

(2013) Yu Li et al.   GASTROENTEROLOGY

Interferon regulatory factor 3 constrains IKKβ/NF-κB signaling to alleviate hepatic steatosis and insulin resistance

(2013) Xin-An Wang et al.   HEPATOLOGY

Mechanisms for Insulin Resistance: Common Threads and Missing Links

(2012) Varman T. Samuel et al.   CELL

The diagnosis and management of non-alcoholic fatty liver disease: Practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association

(2012) Naga Chalasani et al.   HEPATOLOGY

Hepatic overexpression of SIRT1 in mice attenuates endoplasmic reticulum stress and insulin resistance in the liver

(2011) Yu Li et al.   FASEB JOURNAL

Anti-inflammatory potential of allyl-isothiocyanate - role of Nrf2, NF-κB and microRNA-155

(2011) Anika Eva Wagner et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Human Fatty Liver Disease: Old Questions and New Insights

(2011) J. C. Cohen et al.   SCIENCE

SIRT1 Deacetylates and Inhibits SREBP-1C Activity in Regulation of Hepatic Lipid Metabolism

(2010) Bhaskar Ponugoti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multidirectional Time-Dependent Effect of Sinigrin and Allyl Isothiocyanate on Metabolic Parameters in Rats

(2010) Monika Okulicz   PLANT FOODS FOR HUMAN NUTRITION

Hepatocyte-Specific Deletion of SIRT1 Alters Fatty Acid Metabolism and Results in Hepatic Steatosis and Inflammation

(2009) Aparna Purushotham et al.   Cell Metabolism

Heme Oxygenase-1 Protects Against Steatohepatitis in Both Cultured Hepatocytes and Mice

(2009) Jun Yu et al.   GASTROENTEROLOGY

Allyl isothiocyanate as a cancer chemopreventive phytochemical

(2009) Yuesheng Zhang   MOLECULAR NUTRITION & FOOD RESEARCH

Specific SIRT1 Activation Mimics Low Energy Levels and Protects against Diet-Induced Metabolic Disorders by Enhancing Fat Oxidation

(2008) Jérôme N. Feige et al.   Cell Metabolism

SIRT1 Regulates Hepatocyte Lipid Metabolism through Activating AMP-activated Protein Kinase

(2008) Xiuyun Hou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sirt1 protects against high-fat diet-induced metabolic damage

(2008) P. T. Pfluger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA