Article
Chemistry, Multidisciplinary
Bochao Chen, Shumei Mao, Yanyan Sun, Liyuan Sun, Ning Ding, Chengde Li, Jin Zhou
Summary: A mitochondria-targeted fluorescent probe NIR-V with 700 nm emission was designed to monitor cell viscosity changes with high selectivity and sensitivity, which was applied to detect intracellular viscosity and image pancreatic tissue in a diabetic mouse model. Probe NIR-V provides an effective way to diagnose viscosity related diseases.
CHEMICAL COMMUNICATIONS
(2021)
Article
Chemistry, Applied
Liren Xu, Jin Yu, Yunpeng Wang, Yuru Chen, Xiaoli Zhang, Rubing Han, Jing Jing, Rubo Zhang, Xiaoling Zhang
Summary: In this study, a fluorescent probe PCH was synthesized to detect ClO- in mitochondria. PCH can target mitochondria with fast response speed, high selectivity, large Stokes shift, and low detection limitation. With this probe, mitochondrial ClO- can be detected endogenously and exogenously.
Article
Spectroscopy
Mengwen Yi, Xiangjun Liu, Jing Liu, Shengnan Li, Dandan Li, Xiangru Zhang, Nan Zhang, Yongbiao Wei, Dihua Shangguan
Summary: A new near-infrared fluorescent probe A1 with good mitochondria targeting ability was developed for colorimetric and fluorescence detection of HSO3-. It has potential applications in biological systems.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Applied
Jinshuai Lan, Yu Wang, Yanhong Qin, Zhe Li, Ruifeng Zeng, Li Liu, Lixia Chen, Kaixu Yang, Yue Ding, Tong Zhang
Summary: In this study, a novel dual-site mitochondria-targeted fluorescent probe was developed for the simultaneous detection of SO2 derivatives and ClO-. The probe exhibited distinct fluorescence for each target, and demonstrated good selectivity, high sensitivity and rapid response.
Article
Chemistry, Analytical
Wan Sun, Xiangling Gu, Pingxuan Dong, Lianjun Chu, Zhongyu Zhang, Zhenyuan Cheng, Fan Yang
Summary: In this study, a membrane-targeted near-infrared small molecule fluorescent probe was developed for the detection of extracellular ATP. This probe showed high sensitivity and specificity, enabling quantitative detection of extracellular ATP in tumor diagnosis and treatment.
Article
Spectroscopy
Xiao Wang, Xuechuan Wang, Qiangqiang Lu, Xiaolong Sun, Qingxing Han
Summary: The study designed and synthesized a NIR probe, named W-1a, for specific detection of hypochlorite. The probe exhibited dual fluorescence and colorimetric sensing with a fast response time and low detection limit. It was successfully applied for fluorescence imaging of hypochlorite at the cellular level and toxicity assessment in dairy products.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Chemistry, Analytical
Shixuan An, Yanfei Lin, Jianbo Wang, Tianqing Ye, Yanyun Mao, Jian Zhang, Longhua Guo, Lei Li, Zhaosheng Qian, Haiying Liu
Summary: In this study, a novel near-infrared fluorescent probe was designed and developed for the detection and fluorescence imaging of cysteine/homocysteine. The probe exhibited rapid response and high sensitivity, with a detection limit of 46 nM for cysteine. Additionally, the probe could be employed for imaging and detection in living cells and in vivo.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Analytical
Aishan Zheng, Han Liu, Chuanhao Peng, Xiaonan Gao, Kehua Xu, Bo Tang
Summary: CVS is a mitochondria-targeting near-Infrared fluorescent probe designed for sensing and detecting HOCl with high selectivity and low detection limit. It has been successfully applied to image HOCl in mitochondria of HepG2 cells, providing a perspective method for further study of physiological and pathological functions related to HOCl.
Article
Biochemistry & Molecular Biology
Chang-Xiang Liu, Shu-Yuan Xiao, Xiu-Lin Gong, Xi Zhu, Ya-Wen Wang, Yu Peng
Summary: A novel near-infrared (NIR) fluorescent probe, SWJT-9, was designed and synthesized for the detection of hypochlorite anion (ClO-), showing excellent NIR fluorescence response with a color change under visible light. SWJT-9 demonstrated high selectivity, low detection limit (24.7 nM), and rapid detection (within 2 minutes) for ClO-. The detection mechanism of SWJT-9 on ClO- was confirmed using H-1 NMR, MS spectrum, and density functional theory (DFT) calculations.
Article
Chemistry, Analytical
Xueling Liu, Yali Wang, Guangshuai Zhou, Wenzhou Zhang
Summary: This study developed a fluorescent probe mito-ACS for imaging mitochondrial hypochlorite in living cells. The probe exhibited fast response, low detection limit, good water solubility, and selective localization to mitochondria. It showed great potential in fluorescent imaging of biological systems.
Article
Chemistry, Analytical
Hai Xu, Song-Ling Wu, Nai-Jie Lin, Yuan Lu, Jian Xiao, Ya-Wen Wang, Yu Peng
Summary: The near-infrared fluorescent probe SWJT-1, based on C=N isomerization, shows excellent response to ClO with low detection limit, high selectivity, and rapid detection. The sensing mechanism of SWJT-1 for ClO has been confirmed through various analytical techniques, and it has been successfully applied in bioimaging for the detection of ClO in vitro and vivo.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Analytical
Jing-Jing Chao, Hui Zhang, Zhi-Qing Wang, Qiao-Rong Liu, Guo-Jiang Mao, Dong-Hua Chen, Chun-Yan Li
Summary: A near-infrared fluorescence probe (QX-V) based on quinoline-xanthene dye was developed for detecting viscosity, which is associated with diseases like tumor and fatty liver. The probe showed high sensitivity and good selectivity, and had long excitation and emission wavelengths. It could target mitochondria and image viscosity abnormality in tumor-bearing mice and fatty-liver mice.
ANALYTICA CHIMICA ACTA
(2023)
Article
Spectroscopy
Sheng Wang, Yu Zhang, Tian-Ran Wang, Yu-Jun Liu, Shi-Li Shen, Xiao-Qun Cao
Summary: Hydrogen peroxide (H2O2) is a crucial member of reactive oxygen species, playing critical roles in oxidative stress and cell signaling. Abnormal levels of intracellular H2O2 production are closely related to many diseases, highlighting the importance of real-time monitoring. The novel fluorescent probe Mito-H2O2 shows fast response, excellent water solubility, and significant fluorescence intensity enhancement, making it successful for imaging H2O2 in cells and mice with minimal cytotoxicity.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Engineering, Environmental
Li Fan, Qi Zan, Xiaodong Wang, Xue Yu, Shuohang Wang, Yuewei Zhang, Qianqian Yang, Wenjing Lu, Shaomin Shuang, Chuan Dong
Summary: In this study, we designed a mitochondria-targeted and viscosity-sensitive near-infrared fluorescent probe POTA-OH capable of visualizing mitochondrial viscosity in multiple disease models and achieving photodynamic cancer therapy. The probe showed excellent linear relationship and fluorescence properties, emitting significant fluorescence signals at different viscosities and generating reactive oxygen species upon red light excitation. Using this probe, we successfully visualized fatty liver, inflammation, and cancer tissues in vivo and in vitro and demonstrated its potential for photodynamic therapy.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Materials Science, Multidisciplinary
Chenglu Zhang, Yiming Wang, Lu Zhang, Xiangling Li, Shiru Nie, Chang Liu
Summary: The novel probe BPQO can specifically and sensitively detect hypochlorite and cyanide, with response processes completed quickly and low toxicity, making it suitable for cell imaging detection.
Article
Spectroscopy
Zh. E. Ozbekova, A. A. Abdyldaev, A. A. Kulmyrzaev
Summary: This study compared two drying methods for cow and yak muscles, finding that freeze drying caused less discoloration. Additionally, analysis of fluorescence spectra allowed for accurate prediction of chemical composition and color characteristics of the muscles.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Leo Mandic, Ivan Ljubic, Iva Dzeba
Summary: In this study, a combined experimental and computational approach was used to investigate the photoexcitation and photodegradation mechanisms of Doxazosin (DOX). The results provide valuable insights into the primary events following the photoexcitation of DOX and its potential applications.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Xiufeng Wang, Yao Jin, Wenhui Ai, Siqi Wang, Zhiqing Zhang, Ting Zhou, Fang Wang, Guodong Zhang
Summary: This study successfully synthesized near infrared fluorescence Ag2S quantum dots (QDs) and developed a dual-mode sensor for sulfide anion using the excellent oxidase-like characteristics of manganese dioxide (MnO2) nanosheets. The sensor showed a wider detection range, higher sensitivity, and shorter reaction time, making it suitable for highly selective detection of sulfide in different concentration ranges.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Yafei Li, Yanming Ma, Chuantao Zheng, Di Yu, Lien Hu, Shuo Yang, Fang Song, Yadan Li, Shuanghai Liu, Zhanrui Zhang, Yu Zhang, Yiding Wang, Frank K. Tittel
Summary: To effectively monitor gas explosion and coal spontaneous combustion in coal mine, an intrinsically safe and explosion-proof dual-gas sensor system was developed for methane (CH4) and carbon monoxide (CO) measurement. The system achieved different measurement ranges using laser scanning and gas cells, and improved stability and accuracy through gas pre-treatment and temperature compensation algorithm.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Pei-Rong Chen, Li-Kang Chu
Summary: In this study, the hydrates of glyoxal were investigated using infrared absorption spectrometry. The results showed that at low concentrations, glyoxal mainly exists as monomeric dihydrate. These findings provide suitable detection windows for further research on the roles of glyoxal and its hydrates in atmospheric and aerosol chemistry, as well as the relevant reaction kinetics.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Nichole O'Neill, Thamires A. Lima, Fabio Furlan Ferreira, Nicolas J. Alvarez, Reinhard Schweitzer-Stenner
Summary: This study determines the main fibril axis of GHG gel-forming fibrils using various techniques and compares the results with simulated data. The analysis suggests that the hydrophobic xz-surfaces of GHG fibrils could be a good target for the adsorption of hydrophobic drugs.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Mengyuan Liu, Hanchuang Zhu, Yikun Fang, Caiyun Liu, Xinke Li, Xiaohui Zhang, Lixue Ma, Kun Wang, Miaohui Yu, Wenlong Sheng, Baocun Zhu
Summary: ABHS is an efficient fluorescent probe that can accurately and sensitively detect Al3+ with strong resistance to interference. It also demonstrates excellent detection and imaging capabilities in complex real samples.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Ahmed S. El-Shafie, Evana Rahman, Yasser Gadelhak, Rehab Mahmoud, Marwa El-Azary
Summary: The recycling of waste mandarin peels into biochar (MRBC) has been used as a high performance and cost-effective adsorbent for treating polluted wastewater effluents. Batch adsorption studies were conducted to analyze the adsorption competency of MRBC on two dyes, methylene blue (MB) and basic fuchsin (BF), either in individual solutions or binary combinations. The results showed that MRBC was capable of effectively removing a high percentage of both dyes. However, the adsorption capacity decreased when the dyes were combined. The cost estimation of MRBC production and wastewater treatment indicated that both were relatively low.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Anindita Bhatta, Jahnabi Upadhyaya, Dipak Chamlagai, Lincoln Dkhar, Pynskhemborlang T. Phanrang, Mohan Rao Kollipara, Sivaprasad Mitra
Summary: Derivatives of thiazole-pyrazole fused benzo-coumarin compounds were synthesized and their photophysical properties were investigated. The synthesized coumarin compounds showed potential as therapeutic agents for Alzheimer's disease, inhibiting acetylcholinesterase activity. The presence of human serum albumin was found to affect the inhibition activity.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Yongwei Duan, Quancheng Liu, Yiju Zhu, Qi Zhang, Xiaohui Duan, Hu Deng, Liping Shang
Summary: In this study, the phase transition of CL-20 was observed using terahertz spectroscopy, and quantum chemical calculations were employed to analyze the vibrations. The results indicated changes in the vibrations of CL-20 before and after phase transition.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Yuefeng Gao, Sai Xu, Baojiu Chen
Summary: This study synthesized Cs2NaInCl6 nanocrystals co-doped with Sb3+ and Tb3+ ions as probes for copper ions detection in lubricating oil. The introduction of Sb3+ effectively reduced the band gap of the host material and enabled energy transfer pathway for Tb3+ emission. The doped Tb3+ ions resulted in the suppression of emission due to electron transfer. The Cs2NaInCl6: 2.5 %Sb3+, 40 %Tb3+ NCs exhibited superior sensitivity and selectivity for copper ions detection.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Yu Liu, Yue Zhang, Changyao Liu, Ce Wang, Baocai Xu, Li Zhao
Summary: A highly sensitive detection platform for heparin was developed using a cationic fluorescent dye (cresyl violet acetate) as a fluorescence probe. The platform demonstrated high selectivity towards heparin and achieved detection in both HEPES solution and serum.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Lopamudra Roy, Nivedita Pan, Susmita Mondal, Ria Ghosh, Md. Nur Hasan, Neha Bhattacharyya, Soumendra Singh, Kallol Bhattacharyya, Arpita Chattopadhyay, Samir Kumar Pal
Summary: The study focuses on the interaction between reactive oxygen species (ROS) and a spectroscopic probe called Rose Bengal (RB), encapsulated in nanoscopic sodium dodecyl sulphate (SDS) micelles and entrapped in microscopic nylon 66 solid matrix. The research demonstrates efficient interaction between ROS and RB-SDS, and investigates the mechanism of hydroxyl radicals generation. Based on these findings, a prototype device utilizing RB embedded in a nylon thin film for quantification of ROS in extracellular fluids and food materials was developed.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Xiaosong Sun, Qihao Cui, Wenyue Dong, Qian Duan, Teng Fei
Summary: Conjugated porous polymers (CPPs) are promising sensing materials and their application in aqueous media is limited. In this study, we synthesized CPPs with porous structure and prepared nanoparticles, enabling efficient photoluminescence sensing of nitroaromatic explosives in aqueous phase.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Maria Cristina Caggiani, Germana Barone, Paolo Mazzoleni
Summary: Raman spectroscopy is commonly used for studying glassy materials in cultural heritage, but it is more difficult to interpret the spectra and apply the technique with portable instruments. In contrast, diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS) can be used in archaeometric investigations as it is portable and non-invasive. However, there is limited application of this technique to historical glasses. This exploratory work demonstrates the potential of DRIFTS, in combination with portable X-ray Fluorescence (pXRF) and EDS microanalyses, for studying the composition and alteration of glass samples in cultural heritage.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)