Tumor-derived TGF-β inhibits mitochondrial respiration to suppress IFN-γ production by human CD4+ T cells
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Title
Tumor-derived TGF-β inhibits mitochondrial respiration to suppress IFN-γ production by human CD4+ T cells
Authors
Keywords
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Journal
Science Signaling
Volume 12, Issue 599, Pages eaav3334
Publisher
American Association for the Advancement of Science (AAAS)
Online
2019-09-18
DOI
10.1126/scisignal.aav3334
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Note: Only part of the references are listed.- Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses
- (2015) Ping-Chih Ho et al. CELL
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- (2015) Ai-Di Gu et al. IMMUNITY
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- (2015) D. S. Thommen et al. Cancer Immunology Research
- Human regulatory T cells lack the cyclophosphamide-extruding transporter ABCB1 and are more susceptible to cyclophosphamide-induced apoptosis
- (2014) Sarah Dimeloe et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Obesity- and aging-induced excess of central transforming growth factor-β potentiates diabetic development via an RNA stress response
- (2014) Jingqi Yan et al. NATURE MEDICINE
- Comprehensive measurement of respiratory activity in permeabilized cells using extracellular flux analysis
- (2014) Joshua K Salabei et al. Nature Protocols
- TGF-β Activation and Function in Immunity
- (2013) Mark A. Travis et al. Annual Review of Immunology
- Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis
- (2013) Chih-Hao Chang et al. CELL
- Rapid effector function of memory CD8+ T cells requires an immediate-early glycolytic switch
- (2013) Patrick M Gubser et al. NATURE IMMUNOLOGY
- Fueling Immunity: Insights into Metabolism and Lymphocyte Function
- (2013) E. L. Pearce et al. SCIENCE
- Expanding Roles for CD4 T Cells and Their Subpopulations in Tumor Immunity and Therapy
- (2013) Mark J. Dobrzanski Frontiers in Oncology
- Ivermectin is a specific inhibitor of importin α/β-mediated nuclear import able to inhibit replication of HIV-1 and dengue virus
- (2012) Kylie M. Wagstaff et al. BIOCHEMICAL JOURNAL
- Metabolic reprogramming of cancer-associated fibroblasts by TGF-β drives tumor growth: Connecting TGF-β signaling with “Warburg-like” cancer metabolism and L-lactate production
- (2012) Carmela Guido et al. CELL CYCLE
- GSK3 inactivation is involved in mitochondrial complex IV defect in transforming growth factor (TGF) β1-induced senescence
- (2012) Hae-Ok Byun et al. EXPERIMENTAL CELL RESEARCH
- Impact of high glucose and transforming growth factor–β on bioenergetic profiles in podocytes
- (2012) Nicole Stieger et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Protection from Obesity and Diabetes by Blockade of TGF-β/Smad3 Signaling
- (2011) Hariom Yadav et al. Cell Metabolism
- Apoptotic role of TGF-β mediated by Smad4 mitochondria translocation and cytochrome c oxidase subunit II interaction
- (2011) Lijuan Pang et al. EXPERIMENTAL CELL RESEARCH
- Cutting Edge: Distinct Glycolytic and Lipid Oxidative Metabolic Programs Are Essential for Effector and Regulatory CD4+ T Cell Subsets
- (2011) R. D. Michalek et al. JOURNAL OF IMMUNOLOGY
- Transforming Growth Factor-β Signaling Curbs Thymic Negative Selection Promoting Regulatory T Cell Development
- (2010) Weiming Ouyang et al. IMMUNITY
- A Comprehensive Resource of Interacting Protein Regions for Refining Human Transcription Factor Networks
- (2010) Etsuko Miyamoto-Sato et al. PLoS One
- TGF-β and immune cells: an important regulatory axis in the tumor microenvironment and progression
- (2010) Li Yang et al. TRENDS IN IMMUNOLOGY
- A critical function for TGF-β signaling in the development of natural CD4+CD25+Foxp3+ regulatory T cells
- (2008) Yongzhong Liu et al. NATURE IMMUNOLOGY
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