Comparative virology of HTLV-1 and HTLV-2

HTLV-1 Tax-1 interacts with SNX27 to regulate cellular localization of the HTLV-1 receptor molecule, GLUT1

(2019) Jacob Al-Saleem et al.   PLoS One

Stability of the HTLV-1 Antisense-Derived Protein, HBZ, Is Regulated by the E3 Ubiquitin-Protein Ligase, UBR5

(2018) Amanda R. Panfil et al.   Frontiers in Microbiology

HTLV Deregulation of the NF-κB Pathway: An Update on Tax and Antisense Proteins Role

(2018) Stefania Fochi et al.   Frontiers in Microbiology

HTLV-1 Tax Induces Formation of the Active Macromolecular IKK Complex by Generating Lys63- and Met1-Linked Hybrid Polyubiquitin Chains

(2017) Yuri Shibata et al.   PLoS Pathogens

Human T-Lymphotropic Virus type 1 infection in an Indigenous Australian population: epidemiological insights from a hospital-based cohort study

(2016) Lloyd Einsiedel et al.   BMC PUBLIC HEALTH

Functional Comparison of HBZ and the Related APH-2 Protein Provides Insight into Human T-Cell Leukemia Virus Type 1 Pathogenesis

(2016) Amanda R. Panfil et al.   JOURNAL OF VIROLOGY

Incidence of human T-lymphotropic virus 1 infection in adolescent and adult blood donors in Japan: a nationwide retrospective cohort analysis

(2016) Masahiro Satake et al.   LANCET INFECTIOUS DISEASES

Infection with human T-lymphotropic virus types-1 and -2 (HTLV-1 and -2): Implications for blood transfusion safety

(2016) E.L. Murphy   TRANSFUSION CLINIQUE ET BIOLOGIQUE

Novel interactions between the HTLV antisense proteins HBZ and APH-2 and the NFAR protein family: Implications for the HTLV lifecycles

(2016) Jane Murphy et al.   VIROLOGY

Human T-cell leukemia virus type 1 (HTLV-1) Tax1 oncoprotein but not HTLV-2 Tax2 induces the expression of OX40 ligand by interacting with p52/p100 and RelB

(2016) Yosuke Motai et al.   VIRUS GENES

Akt Pathway Activation by Human T-cell Leukemia Virus Type 1 Tax Oncoprotein

(2015) Mathew A. Cherian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HTLV-1 Tax protein recruitment into IKKε and TBK1 kinase complexes enhances IFN-I expression

(2015) Erica Diani et al.   VIROLOGY

HTLV-1 Tax Stimulates Ubiquitin E3 Ligase, Ring Finger Protein 8, to Assemble Lysine 63-Linked Polyubiquitin Chains for TAK1 and IKK Activation

(2015) Yik-Khuan Ho et al.   PLoS Pathogens

The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma

(2014) L. B. Cook et al.   BLOOD

Quantification of HTLV-1 Clonality and TCR Diversity

(2014) Daniel J. Laydon et al.   PLoS Computational Biology

Clonality of HTLV-2 in Natural Infection

(2014) Anat Melamed et al.   PLoS Pathogens

HTLV-1 bZIP Factor Suppresses Apoptosis by Attenuating the Function of FoxO3a and Altering Its Localization

(2013) A. Tanaka-Nakanishi et al.   CANCER RESEARCH

HTLV-1 HBZ positively regulates the mTOR signaling pathway via inhibition of GADD34 activity in the cytoplasm

(2013) R Mukai et al.   ONCOGENE

HTLV-2 Tax Immortalizes Human CD4+Memory T Lymphocytes by Oncogenic Activation and Dysregulation of Autophagy

(2012) Tong Ren et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human T-Cell Leukemia Virus Type 2 Antisense Viral Protein 2 Is Dispensable forIn VitroImmortalization but Functions To Repress Early Virus ReplicationIn Vivo

(2012) Han Yin et al.   JOURNAL OF VIROLOGY

Distinct Transformation Tropism Exhibited by Human T Lymphotropic Virus Type 1 (HTLV-1) and HTLV-2 Is the Result of Postinfection T Cell Clonal Expansion

(2012) P. Kannian et al.   JOURNAL OF VIROLOGY

Human T Cell Leukemia Virus Type 2 Tax-Mediated NF- B Activation Involves a Mechanism Independent of Tax Conjugation to Ubiquitin and SUMO

(2012) C. Journo et al.   JOURNAL OF VIROLOGY

HTLV-1 bZIP factor dysregulates the Wnt pathways to support proliferation and migration of adult T-cell leukemia cells

(2012) G Ma et al.   ONCOGENE

Ubiquitination and sumoylation of the HTLV-2 Tax-2B protein regulate its NF-κB activity: a comparative study with the HTLV-1 Tax-1 protein

(2012) Marco Turci et al.   Retrovirology

Epidemiological Aspects and World Distribution of HTLV-1 Infection

(2012) Antoine Gessain et al.   Frontiers in Microbiology

HTLV-1 HBZ Protein Deregulates Interactions between Cellular Factors and the KIX Domain of p300/CBP

(2011) Pamela R. Cook et al.   JOURNAL OF MOLECULAR BIOLOGY

ATF3, an HTLV-1 bZip factor binding protein, promotes proliferation of adult T-cell leukemia cells

(2011) Keita Hagiya et al.   Retrovirology

Intracellular Localization and Cellular Factors Interaction of HTLV-1 and HTLV-2 Tax Proteins: Similarities and Functional Differences

(2011) Umberto Bertazzoni et al.   Viruses-Basel

Requirement of the human T-cell leukemia virus p12 and p30 products for infectivity of human dendritic cells and macaques but not rabbits

(2010) V. W. Valeri et al.   BLOOD

HTLV-I p30 inhibits multiple S phase entry checkpoints, decreases cyclin E-CDK2 interactions and delays cell cycle progression

(2010) Hicham H Baydoun et al.   Molecular Cancer

Emerging roles for the non-canonical IKKs in cancer

(2010) R R Shen et al.   ONCOGENE

Human T-cell leukemia virus type 1 p8 protein increases cellular conduits and virus transmission

(2010) N. Van Prooyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Association of HTLV Tax proteins with TAK1-binding protein 2 and RelA in calreticulin-containing cytoplasmic structures participates in Tax-mediated NF-κB activation

(2010) Francesca Avesani et al.   VIROLOGY

The pleiotropic protein kinase CK2 phosphorylates HTLV-1 Tax protein in vitro, targeting its PDZ-binding motif

(2010) Carlo Bidoia et al.   VIRUS GENES

Human T-cell leukemia virus type 2 produces a spliced antisense transcript encoding a protein that lacks a classic bZIP domain but still inhibits Tax2-mediated transcription

(2009) M. Halin et al.   BLOOD

HTLV-1 Tax Is a Critical Lipid Raft Modulator That Hijacks IκB Kinases to the Microdomains for Persistent Activation of NF-κB

(2009) Jiannan Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Age and gender specific prevalence of HTLV-1

(2009) Nobuoki Eshima et al.   JOURNAL OF CLINICAL VIROLOGY

Identification of a novel motif responsible for the distinctive transforming activity of human T-cell leukemia virus (HTLV) type 1 Tax1 protein from HTLV-2 Tax2

(2009) Toshiyuki Shoji et al.   Retrovirology

Acetylation of the human T-cell leukemia virus type 1 Tax oncoprotein by p300 promotes activation of the NF-κB pathway

(2009) Julie Lodewick et al.   VIROLOGY

HTLV-2B Tax oncoprotein is modified by ubiquitination and sumoylation and displays intracellular localization similar to its homologue HTLV-1 Tax

(2009) Marco Turci et al.   VIROLOGY

NRP/Optineurin Cooperates with TAX1BP1 to Potentiate the Activation of NF-κB by Human T-Lymphotropic Virus Type 1 Tax Protein

(2009) Chloé Journo et al.   PLoS Pathogens

Human T-cell leukemia virus type 1 bZIP factor selectively suppresses the classical pathway of NF- B

(2008) T. Zhao et al.   BLOOD

An Interaction between the Human T Cell Leukemia Virus Type 1 Basic Leucine Zipper Factor (HBZ) and the KIX Domain of p300/CBP Contributes to the Down-regulation of Tax-dependent Viral Transcription by HBZ

(2008) Isabelle Clerc et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human T-cell leukemia virus type 2 post-transcriptional control protein p28 is required for viral infectivity and persistence in vivo

(2008) Brenda Yamamoto et al.   Retrovirology

The HTLV-1 Tax interactome

(2008) Mathieu Boxus et al.   Retrovirology

HTLV-1 Tax-mediated TAK1 activation involves TAB2 adapter protein

(2007) Qingsheng Yu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS