Angiotensin-converting enzyme 2 attenuates inflammatory response and oxidative stress in hyperoxic lung injury by regulating NF-κB and Nrf2 pathways

Tn ( N -acetyl- d -galactosamine- O -serine/threonine) immunization protects against hyperoxia-induced lung injury in adult mice through inhibition of the nuclear factor kappa B activity

(2018) Chung-Ming Chen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis

(2018) Masayuki Yamamoto et al.   PHYSIOLOGICAL REVIEWS

Vitamin D alleviates lipopolysaccharide-induced acute lung injury via regulation of the renin-angiotensin system

(2017) Jun Xu et al.   Molecular Medicine Reports

Role of Nrf2/HO-1 system in development, oxidative stress response and diseases: an evolutionarily conserved mechanism

(2016) Agnieszka Loboda et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Knockdown of placental growth factor (PLGF) mitigates hyperoxia-induced acute lung injury in neonatal rats: Suppressive effects on NFκB signaling pathway

(2016) Liang Zhang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

TNF and ROS Crosstalk in Inflammation

(2016) Heiko Blaser et al.   TRENDS IN CELL BIOLOGY

Angiotensin-converting enzyme 2 prevents lipopolysaccharide-induced rat acute lung injury via suppressing the ERK1/2 and NF-κB signaling pathways

(2016) Yingchuan Li et al.   Scientific Reports

AAV8-Mediated Angiotensin-Converting Enzyme 2 Gene Delivery Prevents Experimental Autoimmune Uveitis by Regulating MAPK, NF-κB and STAT3 Pathways

(2016) Yiguo Qiu et al.   Scientific Reports

Characterization of the Intrarenal Renin-Angiotensin System in Experimental Alport Syndrome

(2015) Eun Hui Bae et al.   AMERICAN JOURNAL OF PATHOLOGY

Combination therapy with human umbilical cord mesenchymal stem cells and angiotensin-converting enzyme 2 is superior for the treatment of acute lung ischemia-reperfusion injury in rats

(2015) Xiaomiao Zhang et al.   CELL BIOCHEMISTRY AND FUNCTION

Carbocisteine attenuates hydrogen peroxide-induced inflammatory injury in A549 cells via NF-κB and ERK1/2 MAPK pathways

(2015) Wei Wang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Biomarkers in acute lung injury

(2015) Daniela Mokra et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Angiotensin-converting enzyme 2 and angiotensin 1–7: novel therapeutic targets

(2014) Fan Jiang et al.   Nature Reviews Cardiology

Effect of Insulin on ACE2 Activity and Kidney Function in the Non-Obese Diabetic Mouse

(2014) Marta Riera et al.   PLoS One

The effect of magnolol on the toll-like receptor 4/nuclear factor kappa B signaling pathway in lipopolysaccharide-induced acute lung injury in mice

(2012) Fu Yunhe et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Regulation of miRNA-21 by reactive oxygen species-activated ERK/NF-κB in arsenite-induced cell transformation

(2012) Min Ling et al.   FREE RADICAL BIOLOGY AND MEDICINE

Angiotensin converting enzyme 2 abrogates bleomycin-induced lung injury

(2012) G. J. Rey-Parra et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Nox4 regulates Nrf2 and glutathione redox in cardiomyocytes in vivo

(2011) Alison C. Brewer et al.   FREE RADICAL BIOLOGY AND MEDICINE

Sildenafil attenuates LPS-induced pro-inflammatory responses through down-regulation of intracellular ROS-related MAPK/NF-κB signaling pathways in N9 microglia

(2011) Siqi Zhao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Ampelopsin reduces endotoxic inflammation via repressing ROS-mediated activation of PI3K/Akt/NF-κB signaling pathways

(2011) Shimei Qi et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Simple and Rapid Method for the Determination of Uric Acid-Independent Antioxidant Capacity

(2011) Darko Duplancic et al.   MOLECULES

The Keap1–Nrf2 system as an in vivo sensor for electrophiles

(2011) Akira Uruno et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Ginsenoside Rg1 protects against hydrogen peroxide-induced cell death in PC12 cells via inhibiting NF-κB activation

(2010) Qian Liu et al.   NEUROCHEMISTRY INTERNATIONAL

Effect of Polymyxin B-Immobilized Fiber Hemoperfusion on Serum High Mobility Group Box-1 Protein Levels and Oxidative Stress in Patients With Acute Respiratory Distress Syndrome

(2009) Tsukasa Nakamura et al.   ASAIO JOURNAL

Devil and angel in the renin–angiotensin system: ACE–angiotensin II–AT1 receptor axis vs. ACE2–angiotensin-(1–7)–Mas receptor axis

(2009) Masaru Iwai et al.   HYPERTENSION RESEARCH

Humanized monoclonal antibody against the chemokine CXCL-8 (IL-8) effectively prevents acute lung injury

(2009) ZhiYao Bao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

TNF-α inhibitors in asthma and COPD: We must not throw the baby out with the bath water

(2009) Maria Gabriella Matera et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury

(2008) Yumiko Imai et al.   CELL

The discovery of angiotensin-converting enzyme 2 and its role in acute lung injury in mice

(2008) Yumiko Imai et al.   EXPERIMENTAL PHYSIOLOGY