Structural basis for the coordination of cell division with the synthesis of the bacterial cell envelope

Regulation of the Peptidoglycan Polymerase Activity of PBP1b by Antagonist Actions of the Core Divisome Proteins FtsBLQ and FtsN

(2019) Adrien Boes et al.   mBio

The cell cycle regulator GpsB functions as cytosolic adaptor for multiple cell wall enzymes

(2019) Robert M. Cleverley et al.   Nature Communications

FtsW is a peptidoglycan polymerase that is functional only in complex with its cognate penicillin-binding protein

(2019) Atsushi Taguchi et al.   Nature Microbiology

Coordination of capsule assembly and cell wall biosynthesis in Staphylococcus aureus

(2019) Marvin Rausch et al.   Nature Communications

Division plane placement in pleomorphic archaea is dynamically coupled to cell shape

(2019) James C. Walsh et al.   MOLECULAR MICROBIOLOGY

Visualizing conformation transitions of the Lipid II flippase MurJ

(2019) Alvin C. Y. Kuk et al.   Nature Communications

The Cell Wall of Streptococcus pneumoniae

(2019) Waldemar Vollmer et al.   Microbiology Spectrum

The antimicrobial peptide thanatin disrupts the bacterial outer membrane and inactivates the NDM-1 metallo-β-lactamase

(2019) Bo Ma et al.   Nature Communications

Bacterial outer membrane constriction

(2018) Alexander J. F. Egan   MOLECULAR MICROBIOLOGY

Structure and mutagenic analysis of the lipid II flippase MurJ fromEscherichia coli

(2018) Sanduo Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Escherichia coli ZipA Organizes FtsZ Polymers into Dynamic Ring-Like Protofilament Structures

(2018) Marcin Krupka et al.   mBio

Structural Analysis of the Interaction between the Bacterial Cell Division Proteins FtsQ and FtsB

(2018) Danguole Kureisaite-Ciziene et al.   mBio

Structure of the essential peptidoglycan amidotransferase MurT/GatD complex from Streptococcus pneumoniae

(2018) Cécile Morlot et al.   Nature Communications

The structures of penicillin-binding protein 4 (PBP4) and PBP5 from Enterococci provide structural insights into β-lactam resistance

(2018) Thomas M. Moon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Z-ring membrane anchors associate with cell wall synthases to initiate bacterial cell division

(2018) Manuel Pazos et al.   Nature Communications

An essential Staphylococcus aureus cell division protein directly regulates FtsZ dynamics

(2018) Prahathees J Eswara et al.   eLife

Conformational Dynamics in Penicillin-Binding Protein 2a of Methicillin-Resistant Staphylococcus aureus, Allosteric Communication Network and Enablement of Catalysis

(2017) Kiran V. Mahasenan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

ZapA and ZapB form an FtsZ-independent structure at midcell

(2017) Jackson A. Buss et al.   MOLECULAR MICROBIOLOGY

Structural basis for nutrient acquisition by dominant members of the human gut microbiota

(2017) Amy J. Glenwright et al.   NATURE

Treadmilling by FtsZ filaments drives peptidoglycan synthesis and bacterial cell division

(2017) Alexandre W. Bisson-Filho et al.   SCIENCE

RodA as the missing glycosyltransferase in Bacillus subtilis and antibiotic discovery for the peptidoglycan polymerase pathway

(2017) Kaveh Emami et al.   Nature Microbiology

Wall teichoic acids mediate increased virulence in Staphylococcus aureus

(2017) Stefanie Wanner et al.   Nature Microbiology

ZipA and FtsA* stabilize FtsZ-GDP miniring structures

(2017) Yaodong Chen et al.   Scientific Reports

Cell division of Streptococcus pneumoniae : think positive!

(2016) Pierre Simon Garcia et al.   CURRENT OPINION IN MICROBIOLOGY

Subunit Arrangement in GpsB, a Regulator of Cell Wall Biosynthesis

(2016) Robert M. Cleverley et al.   Microbial Drug Resistance

SEDS proteins are a widespread family of bacterial cell wall polymerases

(2016) Alexander J. Meeske et al.   NATURE

Splitsville: structural and functional insights into the dynamic bacterial Z ring

(2016) Daniel P. Haeusser et al.   NATURE REVIEWS MICROBIOLOGY

Protein export through the bacterial Sec pathway

(2016) Alexandra Tsirigotaki et al.   NATURE REVIEWS MICROBIOLOGY

The Redundancy of Peptidoglycan Carboxypeptidases Ensures Robust Cell Shape Maintenance in Escherichia coli

(2016) Katharina Peters et al.   mBio

β-Lactamases: A Focus on Current Challenges

(2016) Robert A. Bonomo   Cold Spring Harbor Perspectives in Medicine

Mechanisms of Methicillin Resistance inStaphylococcus aureus

(2015) Sharon J. Peacock et al.   Annual Review of Biochemistry

Peptidoglycan architecture of Gram-positive bacteria by solid-state NMR

(2015) Sung Joon Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Structure of the bacterial cell division determinant GpsB and its interaction with penicillin-binding proteins

(2015) Jeanine Rismondo et al.   MOLECULAR MICROBIOLOGY

Outer membrane protein biogenesis in Gram-negative bacteria

(2015) Sarah E. Rollauer et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Activities and regulation of peptidoglycan synthases

(2015) Alexander J. F. Egan et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Coordination of peptidoglycan synthesis and outer membrane constriction during Escherichia coli cell division

(2015) Andrew N Gray et al.   eLife

The Min system and other nucleoid-independent regulators of Z ring positioning

(2015) Veronica W. Rowlett et al.   Frontiers in Microbiology

Crystallizing membrane proteins for structure–function studies using lipidic mesophases

(2015) Martin Caffrey   BIOCHEMICAL SOCIETY TRANSACTIONS

Lipoteichoic Acid Synthesis and Function in Gram-Positive Bacteria

(2014) Matthew G. Percy et al.   Annual Review of Microbiology

Inhibitors of the peptidoglycan biosynthesis enzymes MurA-F

(2014) Martina Hrast et al.   BIOORGANIC CHEMISTRY

Beta-Lactam Antibiotics Induce a Lethal Malfunctioning of the Bacterial Cell Wall Synthesis Machinery

(2014) Hongbaek Cho et al.   CELL

Cell cycle regulation by the bacterial nucleoid

(2014) David William Adams et al.   CURRENT OPINION IN MICROBIOLOGY

Specificity of the Transport of Lipid II by FtsW inEscherichia coli

(2014) Tamimount Mohammadi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Staphylococcus aureus DivIB is a peptidoglycan-binding protein that is required for a morphological checkpoint in cell division

(2014) Amy L. Bottomley et al.   MOLECULAR MICROBIOLOGY

Different walls for rods and balls: the diversity of peptidoglycan

(2014) Robert D. Turner et al.   MOLECULAR MICROBIOLOGY

Functional Domain Analysis of the Cell Division Inhibitor EzrA

(2014) Adrian D. Land et al.   PLoS One

MurJ is the flippase of lipid-linked precursors for peptidoglycan biogenesis

(2014) L.-T. Sham et al.   SCIENCE

Structure and function of a spectrin-like regulator of bacterial cytokinesis

(2014) Robert M. Cleverley et al.   Nature Communications

In vitro Reconstitution of Peptidoglycan Assembly from the Gram-Positive Pathogen Streptococcus pneumoniae

(2013) André Zapun et al.   ACS Chemical Biology

Wall Teichoic Acids of Gram-Positive Bacteria

(2013) Stephanie Brown et al.   Annual Review of Microbiology

The bacterial Min system

(2013) Veronica Wells Rowlett et al.   CURRENT BIOLOGY

In the Beginning,Escherichia coliAssembled the Proto-ring: An Initial Phase of Division

(2013) Ana Isabel Rico et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The lipid II flippase RodA determines morphology and growth inCorynebacterium glutamicum

(2013) Boris Sieger et al.   MOLECULAR MICROBIOLOGY

The bacterial cell division proteins FtsA and FtsZ self-organize into dynamic cytoskeletal patterns

(2013) Martin Loose et al.   NATURE CELL BIOLOGY

How allosteric control of Staphylococcus aureus penicillin binding protein 2a enables methicillin resistance and physiological function

(2013) L. H. Otero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of WTA Synthesis Blocks the Cooperative Action of PBPs and Sensitizes MRSA to β-Lactams

(2012) Maya A. Farha et al.   ACS Chemical Biology

The physiology of bacterial cell division

(2012) Alexander J. F. Egan et al.   Annals of the New York Academy of Sciences

Structural Perspective of Peptidoglycan Biosynthesis and Assembly

(2012) Andrew L. Lovering et al.   Annual Review of Biochemistry

A Specific Role for the ZipA Protein in Cell Division

(2012) Manuel Pazos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanism of Action of the Cell-Division Inhibitor PC190723: Modulation of FtsZ Assembly Cooperativity

(2012) Nathaniel L. Elsen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The twin-arginine translocation (Tat) protein export pathway

(2012) Tracy Palmer et al.   NATURE REVIEWS MICROBIOLOGY

Robustness and accuracy of cell division in Escherichia coli in diverse cell shapes

(2012) J. Mannik et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

β-Lactams

(2012) Rúben Fernandes et al.   REVIEWS IN MEDICAL MICROBIOLOGY

Identification of FtsW as a transporter of lipid-linked cell wall precursors across the membrane

(2011) Tamimount Mohammadi et al.   EMBO JOURNAL

Multiple essential roles for EzrA in cell division of Staphylococcus aureus

(2011) Victoria R. Steele et al.   MOLECULAR MICROBIOLOGY

Nucleoid occlusion and bacterial cell division

(2011) Ling Juan Wu et al.   NATURE REVIEWS MICROBIOLOGY

Features critical for membrane binding revealed by DivIVA crystal structure

(2010) Maria A Oliva et al.   EMBO JOURNAL

The Antibacterial Cell Division Inhibitor PC190723 Is an FtsZ Polymer-stabilizing Agent That Induces Filament Assembly and Condensation

(2010) José M. Andreu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Bacterial Cell Envelope

(2010) T. J. Silhavy et al.   Cold Spring Harbor Perspectives in Biology

Peptidoglycan architecture can specify division planes in Staphylococcus aureus

(2010) Robert D. Turner et al.   Nature Communications

Discovery of a Small Molecule that Blocks Wall Teichoic Acid Biosynthesis inStaphylococcus aureus

(2009) Jonathan G. Swoboda et al.   ACS Chemical Biology

Characterization of a New Metallo- -Lactamase Gene, blaNDM-1, and a Novel Erythromycin Esterase Gene Carried on a Unique Genetic Structure in Klebsiella pneumoniae Sequence Type 14 from India

(2009) D. Yong et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Localisation of DivIVA by targeting to negatively curved membranes

(2009) Rok Lenarcic et al.   EMBO JOURNAL

An oldie but a goodie – cell wall biosynthesis as antibiotic target pathway

(2009) Tanja Schneider et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Involvement of an Essential Gene, mviN, in Murein Synthesis in Escherichia coli

(2008) A. Inoue et al.   JOURNAL OF BACTERIOLOGY

Control of the cell elongation–division cycle by shuttling of PBP1 protein in Bacillus subtilis

(2008) Dennis Claessen et al.   MOLECULAR MICROBIOLOGY

Bioinformatics identification of MurJ (MviN) as the peptidoglycan lipid II flippase in Escherichia coli

(2008) N. Ruiz   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipid II: A central component in bacterial cell wall synthesis and a target for antibiotics

(2008) Ben de Kruijff et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

An Inhibitor of FtsZ with Potent and Selective Anti-Staphylococcal Activity

(2008) D. J. Haydon et al.   SCIENCE