Evolution of ageing as a tangle of trade-offs: energy versus function

Evolutionary Ecology of Senescence and a Reassessment of Williams’ ‘Extrinsic Mortality’ Hypothesis

(2019) Jacob Moorad et al.   TRENDS IN ECOLOGY & EVOLUTION

Lifespan extension without fertility reduction following dietary addition of the autophagy activator Torin1 in Drosophila melanogaster

(2018) Janet S. Mason et al.   PLoS One

Horizons in the evolution of aging

(2018) Thomas Flatt et al.   BMC BIOLOGY

C. elegans Eats Its Own Intestine to Make Yolk Leading to Multiple Senescent Pathologies

(2018) Marina Ezcurra et al.   CURRENT BIOLOGY

Translation attenuation by minocycline enhances longevity and proteostasis in old post-stress-responsive organisms

(2018) Gregory M Solis et al.   eLife

Environmental complexity and the purging of deleterious alleles

(2017) Amardeep Singh et al.   EVOLUTION

Antagonistically pleiotropic allele increases lifespan and late-life reproduction at the cost of early-life reproduction and individual fitness

(2017) Alexei A. Maklakov et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The physical environment mediates male harm and its effect on selection in females

(2017) Li Yun et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The Expensive Germline and the Evolution of Ageing

(2016) Alexei A. Maklakov et al.   CURRENT BIOLOGY

The Rarity of Survival to Old Age Does Not Drive the Evolution of Senescence

(2016) Maarten J. Wensink et al.   Evolutionary Biology

Reduced insulin/insulin-like growth factor signaling decreases translation in Drosophila and mice

(2016) Paul Essers et al.   Scientific Reports

Answering the ultimate question “What is the Proximal Cause of Aging?”

(2016) Mikhail V. Blagosklonny   Aging-US

Why organisms age: Evolution of senescence under positive pleiotropy?

(2015) Alexei A. Maklakov et al.   BIOESSAYS

What can long-lived mutants tell us about mechanisms causing aging and lifespan variation in natural environments?

(2015) Michael Briga et al.   EXPERIMENTAL GERONTOLOGY

Repression of the Heat Shock Response Is a Programmed Event at the Onset of Reproduction

(2015) Johnathan Labbadia et al.   MOLECULAR CELL

Early-late life trade-offs and the evolution of ageing in the wild

(2015) J.-F. Lemaitre et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Reproductive effort accelerates actuarial senescence in wild birds: an experimental study

(2014) Jelle J. Boonekamp et al.   ECOLOGY LETTERS

Evolutionary shaping of demographic schedules

(2014) K. W. Wachter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Early life expenditure in sexual competition is associated with increased reproductive senescence in male red deer

(2014) J.-F. Lemaitre et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The Effects of Selective History and Environmental Heterogeneity on Inbreeding Depression in Experimental Populations of Drosophila melanogaster

(2013) Tristan A. F. Long et al.   AMERICAN NATURALIST

Testing the predictions of energy allocation decisions in the evolution of life-history trade-offs

(2013) Amy L. Skibiel et al.   FUNCTIONAL ECOLOGY

Insulin/IGF-1-mediated longevity is marked by reduced protein metabolism

(2013) G. J. Stout et al.   Molecular Systems Biology

Diversity of ageing across the tree of life

(2013) Owen R. Jones et al.   NATURE

The age-specific force of natural selection and biodemographic walls of death

(2013) K. W. Wachter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Senescence in natural populations of animals: Widespread evidence and its implications for bio-gerontology

(2012) Daniel H. Nussey et al.   AGEING RESEARCH REVIEWS

Genetics of Longevity in Model Organisms: Debates and Paradigm Shifts

(2012) David Gems et al.   Annual Review of Physiology

Alternative Perspectives on Aging in Caenorhabditis elegans: Reactive Oxygen Species or Hyperfunction?

(2012) David Gems et al.   ANTIOXIDANTS & REDOX SIGNALING

Programmatic features of aging originating in development: aging mechanisms beyond molecular damage?

(2012) João Pedro de Magalhães   FASEB JOURNAL

Prediction of C. elegans Longevity Genes by Human and Worm Longevity Networks

(2012) Robi Tacutu et al.   PLoS One

Life Span Extension via eIF4G Inhibition Is Mediated by Posttranscriptional Remodeling of Stress Response Gene Expression in C. elegans

(2011) Aric N. Rogers et al.   Cell Metabolism

Growth stimulation leads to cellular senescence when the cell cycle is blocked

(2010) Zoya N. Demidenko et al.   CELL CYCLE

Aging: ROS or TOR

(2010) Mikhail V Blagosklonny   CELL CYCLE

Mechanisms of Life Span Extension by Rapamycin in the Fruit Fly Drosophila melanogaster

(2010) Ivana Bjedov et al.   Cell Metabolism

Survival costs of reproduction in Drosophila

(2010) Thomas Flatt   EXPERIMENTAL GERONTOLOGY

Selection for a dominant oncogene and large male size as a risk factor for melanoma in the Xiphophorus animal model

(2010) ANDRÉ A. FERNANDEZ et al.   MOLECULAR ECOLOGY

Erratum: The genetics of ageing

(2010) Cynthia J. Kenyon   NATURE

The genetics of ageing

(2010) Cynthia J. Kenyon   NATURE

Mutation and the evolution of ageing: from biometrics to system genetics

(2010) K. A. Hughes   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Age at the onset of senescence in birds and mammals is predicted by early-life performance

(2010) G. Peron et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

SEX DIFFERENCES, SEXUAL SELECTION, AND AGEING: AN EXPERIMENTAL EVOLUTION APPROACH

(2009) Alexei A. Maklakov et al.   EVOLUTION

Use of stable isotopes to examine how dietary restriction extends Drosophila lifespan

(2008) Diane M. O'Brien et al.   CURRENT BIOLOGY

Ageing and the regulation of protein synthesis: a balancing act?

(2008) Nektarios Tavernarakis   TRENDS IN CELL BIOLOGY