Differential requirements for FcγR engagement by protective antibodies against Ebola virus
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Differential requirements for FcγR engagement by protective antibodies against Ebola virus
Authors
Keywords
-
Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 116, Issue 40, Pages 20054-20062
Publisher
Proceedings of the National Academy of Sciences
Online
2019-09-05
DOI
10.1073/pnas.1911842116
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- A Two-Antibody Pan-Ebolavirus Cocktail Confers Broad Therapeutic Protection in Ferrets and Nonhuman Primates
- (2019) Zachary A. Bornholdt et al. Cell Host & Microbe
- Development of a Human Antibody Cocktail that Deploys Multiple Functions to Confer Pan-Ebolavirus Protection
- (2019) Anna Z. Wec et al. Cell Host & Microbe
- Early human B cell response to Ebola virus in four U.S. survivors of infection
- (2019) Lauren Williamson et al. JOURNAL OF VIROLOGY
- Longitudinal Analysis of the Human B Cell Response to Ebola Virus Infection
- (2019) Carl W. Davis et al. CELL
- Multifunctional Pan-ebolavirus Antibody Recognizes a Site of Broad Vulnerability on the Ebolavirus Glycoprotein
- (2018) Pavlo Gilchuk et al. IMMUNITY
- Identification of Combinations of Approved Drugs With Synergistic Activity Against Ebola Virus in Cell Cultures
- (2018) Julie Dyall et al. JOURNAL OF INFECTIOUS DISEASES
- Broadly neutralizing antibodies from human survivors target a conserved site in the Ebola virus glycoprotein HR2–MPER region
- (2018) Andrew I. Flyak et al. Nature Microbiology
- Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection
- (2018) Erica Ollmann Saphire et al. CELL
- A Role for Fc Function in Therapeutic Monoclonal Antibody-Mediated Protection against Ebola Virus
- (2018) Bronwyn M. Gunn et al. Cell Host & Microbe
- Asymmetric antiviral effects of ebolavirus antibodies targeting glycoprotein stem and glycan cap
- (2018) Philipp A. Ilinykh et al. PLoS Pathogens
- Early antibody therapy can induce long-lasting immunity to SHIV
- (2017) Yoshiaki Nishimura et al. NATURE
- Alveolar macrophages are critical for broadly-reactive antibody-mediated protection against influenza A virus in mice
- (2017) Wenqian He et al. Nature Communications
- In Vivo Production of Monoclonal Antibodies by Gene Transfer via Electroporation Protects against Lethal Influenza and Ebola Infections
- (2017) Chasity D. Andrews et al. Molecular Therapy-Methods & Clinical Development
- Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency
- (2016) Stylianos Bournazos et al. CELL
- Broadly neutralizing anti-influenza antibodies require Fc receptor engagement for in vivo protection
- (2016) David J. DiLillo et al. JOURNAL OF CLINICAL INVESTIGATION
- A Randomized, Controlled Trial of ZMapp for Ebola Virus Infection
- (2016) NEW ENGLAND JOURNAL OF MEDICINE
- Optimal activation of Fc-mediated effector functions by influenza virus hemagglutinin antibodies requires two points of contact
- (2016) Paul E. Leon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Epitope specificity plays a critical role in regulating antibody-dependent cell-mediated cytotoxicity against influenza A virus
- (2016) Wenqian He et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A “Trojan horse” bispecific-antibody strategy for broad protection against ebolaviruses
- (2016) Anna Z. Wec et al. SCIENCE
- Protective monotherapy against lethal Ebola virus infection by a potently neutralizing antibody
- (2016) D. Corti et al. SCIENCE
- Enhanced clearance of HIV-1-infected cells by broadly neutralizing antibodies against HIV-1 in vivo
- (2016) C.-L. Lu et al. SCIENCE
- Isolation of potent neutralizing antibodies from a survivor of the 2014 Ebola virus outbreak
- (2016) Z. A. Bornholdt et al. SCIENCE
- Evaluation of the Activity of Lamivudine and Zidovudine against Ebola Virus
- (2016) Yu Cong et al. PLoS One
- Differential Fc-Receptor Engagement Drives an Anti-tumor Vaccinal Effect
- (2015) David J. DiLillo et al. CELL
- Fcγ receptor pathways during active and passive immunization
- (2015) Stylianos Bournazos et al. IMMUNOLOGICAL REVIEWS
- The role of Fc–FcγR interactions in IgG-mediated microbial neutralization
- (2015) Stylianos Bournazos et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Macaque Monoclonal Antibodies Targeting Novel Conserved Epitopes within Filovirus Glycoprotein
- (2015) Zhen-Yong Keck et al. JOURNAL OF VIROLOGY
- Pan-ebolavirus and Pan-filovirus Mouse Monoclonal Antibodies: Protection against Ebola and Sudan Viruses
- (2015) Frederick W. Holtsberg et al. JOURNAL OF VIROLOGY
- A screen of approved drugs and molecular probes identifies therapeutics with anti–Ebola virus activity
- (2015) Lisa M. Johansen et al. Science Translational Medicine
- Broadly Neutralizing Anti-HIV-1 Antibodies Require Fc Effector Functions for In Vivo Activity
- (2014) Stylianos Bournazos et al. CELL
- Broadly Neutralizing Antibodies and Viral Inducers Decrease Rebound from HIV-1 Latent Reservoirs in Humanized Mice
- (2014) Ariel Halper-Stromberg et al. CELL
- Human IgG Fc domain engineering enhances antitoxin neutralizing antibody activity
- (2014) Stylianos Bournazos et al. JOURNAL OF CLINICAL INVESTIGATION
- Broadly neutralizing hemagglutinin stalk–specific antibodies require FcγR interactions for protection against influenza virus in vivo
- (2014) David J DiLillo et al. NATURE MEDICINE
- Second Generation Inactivated Eastern Equine Encephalitis Virus Vaccine Candidates Protect Mice against a Lethal Aerosol Challenge
- (2014) Shelley P. Honnold et al. PLoS One
- Molecular Characterization of the Monoclonal Antibodies Composing ZMAb: A Protective Cocktail Against Ebola Virus
- (2014) Jonathan Audet et al. Scientific Reports
- Therapeutic Intervention of Ebola Virus Infection in Rhesus Macaques with the MB-003 Monoclonal Antibody Cocktail
- (2013) J. Pettitt et al. Science Translational Medicine
- Sustained protection against Ebola virus infection following treatment of infected nonhuman primates with ZMAb
- (2013) Xiangguo Qiu et al. Scientific Reports
- Protective Efficacy of Neutralizing Monoclonal Antibodies in a Nonhuman Primate Model of Ebola Hemorrhagic Fever
- (2012) Andrea Marzi et al. PLoS One
- A mouse model for HIV-1 entry
- (2012) J. Pietzsch et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mouse model recapitulating human Fc receptor structural and functional diversity
- (2012) P. Smith et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Delayed treatment of Ebola virus infection with plant-derived monoclonal antibodies provides protection in rhesus macaques
- (2012) G. G. Olinger et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A shared structural solution for neutralizing ebolaviruses
- (2011) João M Dias et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Fc-engineered anti-CD40 antibody enhances multiple effector functions and exhibits potent in vitro and in vivo antitumor activity against hematologic malignancies
- (2010) H. M. Horton et al. BLOOD
- Antibody-mediated neutralization of Ebola virus can occur by two distinct mechanisms
- (2010) Devon J. Shedlock et al. VIROLOGY
- Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor
- (2008) Jeffrey E. Lee et al. NATURE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now