Genetic ablation of purine salvage in Cryptosporidium parvum reveals nucleotide uptake from the host cell

The incidence, aetiology, and adverse clinical consequences of less severe diarrhoeal episodes among infants and children residing in low-income and middle-income countries: a 12-month case-control study as a follow-on to the Global Enteric Multicenter Study (GEMS)

(2019) Karen L Kotloff et al.   Lancet Global Health

A new family of cell surface located purine transporters in Microsporidia and related fungal endoparasites

(2019) Peter Major et al.   eLife

Life cycle progression and sexual development of the apicomplexan parasite Cryptosporidium parvum

(2019) Jayesh Tandel et al.   Nature Microbiology

Uncovering the essential genes of the human malaria parasitePlasmodium falciparumby saturation mutagenesis

(2018) Min Zhang et al.   SCIENCE

Morbidity, mortality, and long-term consequences associated with diarrhoea from Cryptosporidium infection in children younger than 5 years: a meta-analyses study

(2018) Ibrahim A Khalil et al.   Lancet Global Health

A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes

(2016) Saima M. Sidik et al.   CELL

A nanotherapy strategy significantly enhances anticryptosporidial activity of an inhibitor of bifunctional thymidylate synthase-dihydrofolate reductase from Cryptosporidium

(2015) Anindita Mukerjee et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

A review of the global burden, novel diagnostics, therapeutics, and vaccine targets for cryptosporidium

(2015) William Checkley et al.   LANCET INFECTIOUS DISEASES

Genetic modification of the diarrhoeal pathogen Cryptosporidium parvum

(2015) Sumiti Vinayak et al.   NATURE

Drug Repurposing Screen Reveals FDA-Approved Inhibitors of Human HMG-CoA Reductase and Isoprenoid Synthesis That Block Cryptosporidium parvum Growth

(2013) Kovi Bessoff et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Optimization of Benzoxazole-Based Inhibitors of Cryptosporidium parvum Inosine 5′-Monophosphate Dehydrogenase

(2013) Suresh Kumar Gorla et al.   JOURNAL OF MEDICINAL CHEMISTRY

Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study

(2013) Karen L Kotloff et al.   LANCET

Parasitic infections: Time to tackle cryptosporidiosis

(2013) Boris Striepen   NATURE

Structure–activity relationship study of selective benzimidazole-based inhibitors of Cryptosporidium parvum IMPDH

(2012) Sivapriya Kirubakaran et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Metabolic Labeling of DNA by Purine Analogues in Vivo

(2012) Anne B. Neef et al.   CHEMBIOCHEM

Selective and Potent Urea Inhibitors of Cryptosporidium parvum Inosine 5′-Monophosphate Dehydrogenase

(2012) Suresh Kumar Gorla et al.   JOURNAL OF MEDICINAL CHEMISTRY

The Antibiotic Potential of Prokaryotic IMP Dehydrogenase Inhibitors

(2011) L. Hedstrom et al.   CURRENT MEDICINAL CHEMISTRY

Structural Determinants of Inhibitor Selectivity in Prokaryotic IMP Dehydrogenases

(2010) Deviprasad R. Gollapalli et al.   CHEMISTRY & BIOLOGY

The Reduced Genome of the Parasitic Microsporidian Enterocytozoon bieneusi Lacks Genes for Core Carbon Metabolism

(2010) Patrick J. Keeling et al.   Genome Biology and Evolution

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

The Structural Basis of Cryptosporidium-Specific IMP Dehydrogenase Inhibitor Selectivity

(2010) Iain S. MacPherson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Screening Pipeline for Antiparasitic Agents Targeting Cryptosporidium Inosine Monophosphate Dehydrogenase

(2010) Lisa Sharling et al.   PLoS Neglected Tropical Diseases

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Triazole Inhibitors ofCryptosporidium parvumInosine 5′-Monophosphate Dehydrogenase

(2009) Sushil K. Maurya et al.   JOURNAL OF MEDICINAL CHEMISTRY

Elucidation of the substrate specificity, kinetic and catalytic mechanism of adenylosuccinate lyase from Plasmodium falciparum

(2008) Vinay Bulusu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Targeting a Prokaryotic Protein in a Eukaryotic Pathogen: Identification of Lead Compounds against Cryptosporidiosis

(2008) Nwakaso N. Umejiego et al.   CHEMISTRY & BIOLOGY

A novel route for ATP acquisition by the remnant mitochondria of Encephalitozoon cuniculi

(2008) Anastasios D. Tsaousis et al.   NATURE