Rationally engineered Staphylococcus aureus Cas9 nucleases with high genome-wide specificity
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Title
Rationally engineered Staphylococcus aureus Cas9 nucleases with high genome-wide specificity
Authors
Keywords
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Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume -, Issue -, Pages 201906843
Publisher
Proceedings of the National Academy of Sciences
Online
2019-10-01
DOI
10.1073/pnas.1906843116
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- (2017) Janice S. Chen et al. NATURE
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- (2015) Samuel H. Sternberg et al. NATURE
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- (2015) F. Ann Ran et al. NATURE
- Broadening the targeting range of Staphylococcus aureus CRISPR-Cas9 by modifying PAM recognition
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- (2011) James T Robinson et al. NATURE BIOTECHNOLOGY
- Evaluation of genomic high-throughput sequencing data generated on Illumina HiSeq and Genome Analyzer systems
- (2011) André E Minoche et al. GENOME BIOLOGY
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