Medullary thymic epithelial NF–kB-inducing kinase (NIK)/IKKα pathway shapes autoimmunity and liver and lung homeostasis in mice

Liver NF-κB-Inducing Kinase Promotes Liver Steatosis and Glucose Counterregulation in Male Mice With Obesity

(2017) Yan Liu et al.   ENDOCRINOLOGY

Th17 cytokines: novel potential therapeutic targets for COPD pathogenesis and exacerbations

(2017) Olivier Le Rouzic et al.   EUROPEAN RESPIRATORY JOURNAL

Thymic NF-κB-inducing kinase regulates CD4 + T cell-elicited liver injury and fibrosis in mice

(2017) Hong Shen et al.   JOURNAL OF HEPATOLOGY

Exome Sequencing Identifies a Novel MAP3K14 Mutation in Recessive Atypical Combined Immunodeficiency

(2017) Nikola Schlechter et al.   Frontiers in Immunology

Identification of a Bipotent Epithelial Progenitor Population in the Adult Thymus

(2016) Svetlana Ulyanchenko et al.   Cell Reports

Adult Thymic Medullary Epithelium Is Maintained and Regenerated by Lineage-Restricted Cells Rather Than Bipotent Progenitors

(2015) Izumi Ohigashi et al.   Cell Reports

The role of immune mechanisms in alcoholic and nonalcoholic steatohepatitis: a 2015 update

(2015) Salvatore Sutti et al.   Expert Review of Gastroenterology & Hepatology

The NFκB-inducing kinase is essential for the developmental programming of skin-resident and IL-17-producing γδ T cells

(2015) Florian Mair et al.   eLife

Mouse hepatocyte overexpression of NF-κB-inducing kinase (NIK) triggers fatal macrophage-dependent liver injury and fibrosis

(2014) Hong Shen et al.   HEPATOLOGY

Medullary Thymic Epithelial Stem Cells Maintain a Functional Thymus to Ensure Lifelong Central T Cell Tolerance

(2014) Miho Sekai et al.   IMMUNITY

Biallelic loss-of-function mutation in NIK causes a primary immunodeficiency with multifaceted aberrant lymphoid immunity

(2014) Katharina L. Willmann et al.   Nature Communications

Multilineage Potential and Self-Renewal Define an Epithelial Progenitor Cell Population in the Adult Thymus

(2014) Kahlia Wong et al.   Cell Reports

Autoimmune Features in Metabolic Liver Disease: A Single-Center Experience and Review of the Literature

(2013) Koichi Tsuneyama et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Thymic Medullary Epithelium and Thymocyte Self-Tolerance Require Cooperation between CD28-CD80/86 and CD40-CD40L Costimulatory Pathways

(2013) J. A. Williams et al.   JOURNAL OF IMMUNOLOGY

TRAF3 enforces the requirement for T cell cross-talk in thymic medullary epithelial development

(2013) S. R. Jenkinson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The noncanonical NF-κB pathway

(2012) Shao-Cong Sun   IMMUNOLOGICAL REVIEWS

Noncanonical NF- B regulates inducible costimulator (ICOS) ligand expression and T follicular helper cell development

(2011) H. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Foxn1 Regulates Lineage Progression in Cortical and Medullary Thymic Epithelial Cells But Is Dispensable for Medullary Sublineage Divergence

(2011) Craig S. Nowell et al.   PLoS Genetics

IKKα Is Required to Maintain Skin Homeostasis and Prevent Skin Cancer

(2008) Bigang Liu et al.   CANCER CELL

The Cytokine RANKL Produced by Positively Selected Thymocytes Fosters Medullary Thymic Epithelial Cells that Express Autoimmune Regulator

(2008) Yu Hikosaka et al.   IMMUNITY

The Tumor Necrosis Factor Family Receptors RANK and CD40 Cooperatively Establish the Thymic Medullary Microenvironment and Self-Tolerance

(2008) Taishin Akiyama et al.   IMMUNITY