Developmental programs of lung epithelial progenitors: a balanced progenitor model

Lung development: orchestrating the generation and regeneration of a complex organ

(2014) M. Herriges et al.   DEVELOPMENT

Alveolar progenitor and stem cells in lung development, renewal and cancer

(2014) Tushar J. Desai et al.   NATURE

Apical constriction initiates new bud formation during monopodial branching of the embryonic chicken lung

(2013) H. Y. Kim et al.   DEVELOPMENT

Fgf10-positive cells represent a progenitor cell population during lung development and postnatally

(2013) E. El Agha et al.   DEVELOPMENT

Myb promotes centriole amplification and later steps of the multiciliogenesis program

(2013) F. E. Tan et al.   DEVELOPMENT

Localized Fgf10 expression is not required for lung branching morphogenesis but prevents differentiation of epithelial progenitors

(2013) T. Volckaert et al.   DEVELOPMENT

Development and Regeneration of Sox2+ Endoderm Progenitors Are Regulated by a HDAC1/2-Bmp4/Rb1 Regulatory Pathway

(2013) Yi Wang et al.   DEVELOPMENTAL CELL

Jagged1 is the major regulator of notch-dependent cell fate in proximal airways

(2013) Shubing Zhang et al.   DEVELOPMENTAL DYNAMICS

Multiparametric image analysis of lung-branching morphogenesis

(2013) Carsten Schnatwinkel et al.   DEVELOPMENTAL DYNAMICS

Type 2 alveolar cells are stem cells in adult lung

(2013) Christina E. Barkauskas et al.   JOURNAL OF CLINICAL INVESTIGATION

Nkx2-1 Represses a Latent Gastric Differentiation Program in Lung Adenocarcinoma

(2013) Eric L. Snyder et al.   MOLECULAR CELL

Dedifferentiation of committed epithelial cells into stem cells in vivo

(2013) Purushothama Rao Tata et al.   NATURE

Coordination of heart and lung co-development by a multipotent cardiopulmonary progenitor

(2013) Tien Peng et al.   NATURE

Muc5b is required for airway defence

(2013) Michelle G. Roy et al.   NATURE

Spatiotemporal control of microtubule nucleation and assembly using magnetic nanoparticles

(2013) Céline Hoffmann et al.   Nature Nanotechnology

Deletion of Mesenchymal Glucocorticoid Receptor Attenuates Embryonic Lung Development and Abdominal Wall Closure

(2013) Aiqing Li et al.   PLoS One

Lung epithelial branching program antagonizes alveolar differentiation

(2013) D. R. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sox9 plays multiple roles in the lung epithelium during branching morphogenesis

(2013) B. E. Rockich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Different assemblies of Notch receptors coordinate the distribution of the major bronchial Clara, ciliated and neuroendocrine cells

(2012) M. Morimoto et al.   DEVELOPMENT

CDC42 is required for structural patterning of the lung during development

(2012) Huajing Wan et al.   DEVELOPMENTAL BIOLOGY

Scribble is required for normal epithelial cell–cell contacts and lumen morphogenesis in the mammalian lung

(2012) Laura L. Yates et al.   DEVELOPMENTAL BIOLOGY

Genome-scale study of transcription factor expression in the branching mouse lung

(2012) John C. Herriges et al.   DEVELOPMENTAL DYNAMICS

Genetic studies provide clues on the pathogenesis of idiopathic pulmonary fibrosis

(2012) J. A. Kropski et al.   Disease Models & Mechanisms

Shape Self-Regulation in Early Lung Morphogenesis

(2012) Raphaël Clément et al.   PLoS One

Transcriptional Programs Controlling Perinatal Lung Maturation

(2012) Yan Xu et al.   PLoS One

Integrin Beta 1 Suppresses Multilayering of a Simple Epithelium

(2012) Jichao Chen et al.   PLoS One

Functional characterization of pulmonary neuroendocrine cells in lung development, injury, and tumorigenesis

(2012) H. Song et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuroepithelial body microenvironment is a niche for a distinct subset of Clara-like precursors in the developing airways

(2012) A. Guha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Assessment of morphometry of pulmonary acini in mouse lungs by nondestructive imaging using multiscale microcomputed tomography

(2012) D. M. Vasilescu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Branch Mode Selection during Early Lung Development

(2012) Denis Menshykau et al.   PLoS Computational Biology

A 10-Gene Progenitor Cell Signature Predicts Poor Prognosis in Lung Adenocarcinoma

(2011) Mark Onaitis et al.   ANNALS OF THORACIC SURGERY

Characterization of the cell of origin for small cell lung cancer

(2011) Kwon-Sik Park et al.   CELL CYCLE

Notch-Dependent Differentiation of Adult Airway Basal Stem Cells

(2011) Jason R. Rock et al.   Cell Stem Cell

Notch signaling prevents mucous metaplasia in mouse conducting airways during postnatal development

(2011) Po-Nien Tsao et al.   DEVELOPMENT

Signaling through BMP receptors promotes respiratory identity in the foregut via repression of Sox2

(2011) E. T. Domyan et al.   DEVELOPMENT

Glucocorticoid Activity during Lung Maturation Is Essential in Mesenchymal and Less in Alveolar Epithelial Cells

(2011) Daniel Habermehl et al.   MOLECULAR ENDOCRINOLOGY

cAMP Response Element Binding Protein Is Required for Differentiation of Respiratory Epithelium during Murine Development

(2011) A. Daniel Bird et al.   PLoS One

Control of Mitotic Spindle Angle by the RAS-Regulated ERK1/2 Pathway Determines Lung Tube Shape

(2011) Nan Tang et al.   SCIENCE

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

(2011) Graciana Diez-Roux et al.   PLOS BIOLOGY

FGF10 controls the patterning of the tracheal cartilage rings via Shh

(2010) F. G. Sala et al.   DEVELOPMENT

CARM1 is required for proper control of proliferation and differentiation of pulmonary epithelial cells

(2010) K. B. O'Brien et al.   DEVELOPMENT

Preparing for the First Breath: Genetic and Cellular Mechanisms in Lung Development

(2010) Edward E. Morrisey et al.   DEVELOPMENTAL CELL

The PCP genes Celsr1 and Vangl2 are required for normal lung branching morphogenesis

(2010) Laura L. Yates et al.   HUMAN MOLECULAR GENETICS

Canonical Notch signaling in the developing lung is required for determination of arterial smooth muscle cells and selection of Clara versus ciliated cell fate

(2010) M. Morimoto et al.   JOURNAL OF CELL SCIENCE

Normal Development of the Lung and Premature Birth

(2010) Lucia J. Smith et al.   Paediatric Respiratory Reviews

Reduced Viability of Mice with Lung Epithelial-Specific Knockout of Glucocorticoid Receptor

(2009) Neetu Manwani et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The Role of Scgb1a1+ Clara Cells in the Long-Term Maintenance and Repair of Lung Airway, but Not Alveolar, Epithelium

(2009) Emma L. Rawlins et al.   Cell Stem Cell

The Id2+ distal tip lung epithelium contains individual multipotent embryonic progenitor cells

(2009) E. L. Rawlins et al.   DEVELOPMENT

Notch signaling controls the balance of ciliated and secretory cell fates in developing airways

(2009) P.-N. Tsao et al.   DEVELOPMENT

Notch signaling promotes airway mucous metaplasia and inhibits alveolar development

(2009) J. S. Guseh et al.   DEVELOPMENT

Multiple roles for Sox2 in the developing and adult mouse trachea

(2009) J. Que et al.   DEVELOPMENT

Foregut separation and tracheo-oesophageal malformations: The role of tracheal outgrowth, dorso-ventral patterning and programmed cell death

(2009) Adonis S. Ioannides et al.   DEVELOPMENTAL BIOLOGY

Wnt2/2b and β-Catenin Signaling Are Necessary and Sufficient to Specify Lung Progenitors in the Foregut

(2009) Ashley M. Goss et al.   DEVELOPMENTAL CELL

CYSTIC LUNG DISEASE IN INFANTS AND CHILDREN

(2009) J. Thomas Stocker   Fetal and Pediatric Pathology

Sox2 Is Required for Maintenance and Differentiation of Bronchiolar Clara, Ciliated, and Goblet Cells

(2009) David H. Tompkins et al.   PLoS One

Stem cells are dispensable for lung homeostasis but restore airways after injury

(2009) A. Giangreco et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

 -Catenin promotes respiratory progenitor identity in mouse foregut

(2009) K. S. Harris-Johnson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Basal cells as stem cells of the mouse trachea and human airway epithelium

(2009) J. R. Rock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bronchopulmonary dysplasia and emphysema: in search of common therapeutic targets

(2009) Jacques R. Bourbon et al.   TRENDS IN MOLECULAR MEDICINE

Wnt7b stimulates embryonic lung growth by coordinately increasing the replication of epithelium and mesenchyme

(2008) J. Rajagopal et al.   DEVELOPMENT

Bmp4 is required for tracheal formation: A novel mouse model for tracheal agenesis

(2008) Yina Li et al.   DEVELOPMENTAL BIOLOGY

Sox2 is important for two crucial processes in lung development: Branching morphogenesis and epithelial cell differentiation

(2008) Cristina Gontan et al.   DEVELOPMENTAL BIOLOGY

How to make an alveolus

(2008) E. R. Weibel   EUROPEAN RESPIRATORY JOURNAL

The branching programme of mouse lung development

(2008) Ross J. Metzger et al.   NATURE