CCR2 knockout ameliorates obesity-induced kidney injury through inhibiting oxidative stress and ER stress

C-C Chemokine Receptor 2 Inhibitor Ameliorates Hepatic Steatosis by Improving ER Stress and Inflammation in a Type 2 Diabetic Mouse Model

(2015) Hong-Min Kim et al.   PLoS One

Enhanced glomerular Toll-like receptor 4 expression and signaling in patients with type 2 diabetic nephropathy and microalbuminuria

(2014) Daniela Verzola et al.   KIDNEY INTERNATIONAL

Blockade of CCL2/CCR2 signalling ameliorates diabetic nephropathy in db/db mice

(2013) S. J. Seok et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Expression of fourteen novel obesity-related genes in zucker diabetic fatty rats

(2012) Peter M Schmid et al.   Cardiovascular Diabetology

Inflammation, Endoplasmic Reticulum Stress, Autophagy, and the Monocyte Chemoattractant Protein-1/CCR2 Pathway

(2012) Pappachan E. Kolattukudy et al.   CIRCULATION RESEARCH

High-fat diet induces an initial adaptation of mitochondrial bioenergetics in the kidney despite evident oxidative stress and mitochondrial ROS production

(2011) Christine Ruggiero et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

An orally active chemokine receptor CCR2 antagonist prevents glomerulosclerosis and renal failure in type 2 diabetes

(2011) Sufyan G. Sayyed et al.   KIDNEY INTERNATIONAL

CCR2 antagonism improves insulin resistance, lipid metabolism, and diabetic nephropathy in type 2 diabetic mice

(2010) Young Sun Kang et al.   KIDNEY INTERNATIONAL

Mitochondrial dysfunction and lipotoxicity

(2009) Patrick Schrauwen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Poldip2, a Novel Regulator of Nox4 and Cytoskeletal Integrity in Vascular Smooth Muscle Cells

(2009) Alicia N. Lyle et al.   CIRCULATION RESEARCH

Effect of the Monocyte Chemoattractant Protein-1/CC Chemokine Receptor 2 System on Nephrin Expression in Streptozotocin-Treated Mice and Human Cultured Podocytes

(2009) E. Tarabra et al.   DIABETES

Chemotactic cytokines, obesity and type 2 diabetes: in vivo and in vitro evidence for a possible causal correlation?

(2009) Henrike Sell et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

Metabolic Complications of Childhood Obesity: Identifying and mitigating the risk

(2008) R. Weiss et al.   DIABETES CARE