C-C Chemokine Receptor 2 Inhibitor Ameliorates Hepatic Steatosis by Improving ER Stress and Inflammation in a Type 2 Diabetic Mouse Model

Blockade of CCL2/CCR2 signalling ameliorates diabetic nephropathy in db/db mice

(2013) S. J. Seok et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Insulin Resistance, Ceramide Accumulation and Endoplasmic Reticulum Stress in Experimental Chronic Alcohol-Induced Steatohepatitis

(2012) Teresa Ramirez et al.   ALCOHOL AND ALCOHOLISM

Hepatic recruitment of macrophages promotes nonalcoholic steatohepatitis through CCR2

(2012) Kouichi Miura et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Endoplasmic Reticulum Stress in Nonalcoholic Fatty Liver Disease

(2012) Michael J. Pagliassotti   Annual Review of Nutrition

The Role of Endoplasmic Reticulum in Hepatic Lipid Homeostasis and Stress Signaling

(2012) Suneng Fu et al.   Cell Metabolism

Hepatic mTORC2 Activates Glycolysis and Lipogenesis through Akt, Glucokinase, and SREBP1c

(2012) Asami Hagiwara et al.   Cell Metabolism

Inflammation, Endoplasmic Reticulum Stress, Autophagy, and the Monocyte Chemoattractant Protein-1/CCR2 Pathway

(2012) Pappachan E. Kolattukudy et al.   CIRCULATION RESEARCH

Endoplasmic Reticulum Stress Induces the Expression of Fetuin-A to Develop Insulin Resistance

(2012) Horng-Yih Ou et al.   ENDOCRINOLOGY

Macrophages and Tissue Injury: Agents of Defense or Destruction?

(2011) Debra L. Laskin et al.   Annual Review of Pharmacology and Toxicology

Non-alcoholic fatty liver disease

(2011) Briohny W. Smith et al.   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES

C-C Chemokine Receptor 2 Inhibitor Improves Diet-Induced Development of Insulin Resistance and Hepatic Steatosis in Mice

(2011) Yukinori Tamura et al.   Journal of Atherosclerosis and Thrombosis

Endoplasmic Reticulum Stress-Induced JNK Activation Is a Critical Event Leading to Mitochondria-Mediated Cell Death Caused by β-Lapachone Treatment

(2011) Hyemi Lee et al.   PLoS One

Human Fatty Liver Disease: Old Questions and New Insights

(2011) J. C. Cohen et al.   SCIENCE

Nonalcoholic Fatty Liver Disease: Pathology and Pathogenesis

(2010) Dina G. Tiniakos et al.   Annual Review of Pathology-Mechanisms of Disease

Macrophages, Inflammation, and Insulin Resistance

(2010) Jerrold M. Olefsky et al.   Annual Review of Physiology

Insulin signaling meets mitochondria in metabolism

(2010) Zhiyong Cheng et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Kupffer cell activation is a causal factor for hepatic insulin resistance

(2009) Nicolas Lanthier et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Regulatory Mechanisms for Adipose Tissue M1 and M2 Macrophages in Diet-Induced Obese Mice

(2009) S. Fujisaka et al.   DIABETES

Endoplasmic reticulum stress involved in the course of lipogenesis in fatty acids-induced hepatic steatosis

(2009) Jiang Liu et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Divergent Effects of PERK and IRE1 Signaling on Cell Viability

(2009) Jonathan H. Lin et al.   PLoS One

Inhibition of CCR2 Ameliorates Insulin Resistance and Hepatic Steatosis in db/db Mice

(2008) Yukinori Tamura et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

XBP1 Links ER Stress to Intestinal Inflammation and Confers Genetic Risk for Human Inflammatory Bowel Disease

(2008) Arthur Kaser et al.   CELL

The Role for Endoplasmic Reticulum Stress in Diabetes Mellitus

(2008) Décio L. Eizirik et al.   ENDOCRINE REVIEWS

Discovery of Disubstituted Cyclohexanes as a New Class of CC Chemokine Receptor 2 Antagonists

(2008) Robert J. Cherney et al.   JOURNAL OF MEDICINAL CHEMISTRY