Acute suppression of insulin resistance-associated hepatic miR-29 in vivo improves glycemic control in adult mice

Low plasma adropin concentrations increase risks of weight gain and metabolic dysregulation in response to a high-sugar diet in male nonhuman primates

(2019) Andrew A. Butler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The BCKDH Kinase and Phosphatase Integrate BCAA and Lipid Metabolism via Regulation of ATP-Citrate Lyase

(2018) Phillip J. White et al.   Cell Metabolism

Skeletal Muscle–Specific Deletion of MKP-1 Reveals a p38 MAPK/JNK/Akt Signaling Node That Regulates Obesity-Induced Insulin Resistance

(2018) Ahmed Lawan et al.   DIABETES

Animal models of obesity and diabetes mellitus

(2018) Maximilian Kleinert et al.   Nature Reviews Endocrinology

Identification of microRNA that represses IRS-1 expression in liver

(2018) Kaoru Ono et al.   PLoS One

DNA methylation in the pathogenesis of type 2 diabetes in humans

(2018) Cajsa Davegårdh et al.   Molecular Metabolism

MicroRNA Regulation of the Hyper-Proliferative Phenotype of Vascular Smooth Muscle Cells in Diabetes Mellitus

(2018) Daniele Torella et al.   DIABETES

Control of hepatic gluconeogenesis by Argonaute2

(2018) Xin Yan et al.   Molecular Metabolism

Adipose-derived circulating miRNAs regulate gene expression in other tissues

(2017) Thomas Thomou et al.   NATURE

Salmon provides fast and bias-aware quantification of transcript expression

(2017) Rob Patro et al.   NATURE METHODS

miRNA Signatures of Insulin Resistance in Obesity

(2017) Angela Jones et al.   Obesity

Adropin deficiency worsens HFD-induced metabolic defects

(2017) Shi Chen et al.   Cell Death & Disease

MicroRNA-148a deficiency promotes hepatic lipid metabolism and hepatocarcinogenesis in mice

(2017) Li Cheng et al.   Cell Death & Disease

Dnmt3a is an epigenetic mediator of adipose insulin resistance

(2017) Dongjoo You et al.   eLife

ApoA-IV improves insulin sensitivity and glucose uptake in mouse adipocytes via PI3K-Akt Signaling

(2017) Xiaoming Li et al.   Scientific Reports

Hepatic miR-33a/miR-144 and their target geneABCA1are associated with steatohepatitis in morbidly obese subjects

(2016) Joel Vega-Badillo et al.   LIVER INTERNATIONAL

miR-29a maintains mouse hematopoietic stem cell self-renewal by regulating Dnmt3a

(2015) W. Hu et al.   BLOOD

The microRNA-29 Family Dictates the Balance Between Homeostatic and Pathological Glucose Handling in Diabetes and Obesity

(2015) James Dooley et al.   DIABETES

MicroRNA-148a regulates LDL receptor and ABCA1 expression to control circulating lipoprotein levels

(2015) Leigh Goedeke et al.   NATURE MEDICINE

The microRNA-200 family regulates pancreatic beta cell survival in type 2 diabetes

(2015) Bengt-Frederik Belgardt et al.   NATURE MEDICINE

Transcriptomic Analysis of Chronic Hepatitis B and C and Liver Cancer Reveals MicroRNA-Mediated Control of Cholesterol Synthesis Programs

(2015) Sara R. Selitsky et al.   mBio

Inhibition of miR-29 has a significant lipid-lowering benefit through suppression of lipogenic programs in liver

(2015) C. Lisa Kurtz et al.   Scientific Reports

microRNA-29b prevents liver fibrosis by attenuating hepatic stellate cell activation and inducing apoptosis through targeting PI3K/AKT pathway

(2015) Jia Wang et al.   Oncotarget

MicroRNA-29 Fine-tunes the Expression of Key FOXA2-Activated Lipid Metabolism Genes and Is Dysregulated in Animal Models of Insulin Resistance and Diabetes

(2014) C. L. Kurtz et al.   DIABETES

MicroRNA-7a regulates pancreatic β cell function

(2014) Mathieu Latreille et al.   JOURNAL OF CLINICAL INVESTIGATION

Dnmt3a in Sim1 Neurons Is Necessary for Normal Energy Homeostasis

(2014) D. Kohno et al.   JOURNAL OF NEUROSCIENCE

Elevated microRNA-34a in obesity reduces NAD+levels and SIRT1 activity by directly targeting NAMPT

(2013) Sung-E Choi et al.   AGING CELL

Apolipoprotein A-IV Reduces Hepatic Gluconeogenesis through Nuclear Receptor NR1D1

(2013) Xiaoming Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fish Oil Supplementation Ameliorates Fructose-Induced Hypertriglyceridemia and Insulin Resistance in Adult Male Rhesus Macaques

(2013) Andrew A. Bremer et al.   JOURNAL OF NUTRITION

Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b

(2013) Jan-Wilhelm Kornfeld et al.   NATURE

Beta Cell 5′-Shifted isomiRs Are Candidate Regulatory Hubs in Type 2 Diabetes

(2013) Jeanette Baran-Gale et al.   PLoS One

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

IGF-I 3′ Untranslated Region: Strain-Specific Polymorphisms and Motifs Regulating IGF-I in Osteoblasts

(2012) Spenser S. Smith et al.   ENDOCRINOLOGY

Low Circulating Adropin Concentrations with Obesity and Aging Correlate with Risk Factors for Metabolic Disease and Increase after Gastric Bypass Surgery in Humans

(2012) Andrew A. Butler et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Adropin Deficiency Is Associated With Increased Adiposity and Insulin Resistance

(2012) K. Ganesh Kumar et al.   Obesity

The miR-29 family: genomics, cell biology, and relevance to renal and cardiovascular injury

(2012) Alison J. Kriegel et al.   PHYSIOLOGICAL GENOMICS

MicroRNAs 103 and 107 regulate insulin sensitivity

(2011) Mirko Trajkovski et al.   NATURE

MicroRNA 144 Impairs Insulin Signaling by Inhibiting the Expression of Insulin Receptor Substrate 1 in Type 2 Diabetes Mellitus

(2011) Dwi Setyowati Karolina et al.   PLoS One

MicroRNAs Induced During Adipogenesis that Accelerate Fat Cell Development Are Downregulated in Obesity

(2009) H. Xie et al.   DIABETES

miR-375 maintains normal pancreatic  - and  -cell mass

(2009) M. N. Poy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Development and characterization of a novel rat model of type 2 diabetes mellitus: the UC Davis type 2 diabetes mellitus UCD-T2DM rat

(2008) Bethany P. Cummings et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Downregulation of Diacylglycerol Kinase Delta Contributes to Hyperglycemia-Induced Insulin Resistance

(2008) Alexander V. Chibalin et al.   CELL

Identification of Adropin as a Secreted Factor Linking Dietary Macronutrient Intake with Energy Homeostasis and Lipid Metabolism

(2008) K. Ganesh Kumar et al.   Cell Metabolism