Article
Veterinary Sciences
Lynne U. Sneddon, Paul Schroeder, Ana Roque, Karin Finger-Baier, Angeleen Fleming, Simon Tinman, Bertrand Collet
Summary: Empirical evidence suggests that fishes, including zebrafish, can experience pain. This study reviewed the evidence for pain in zebrafish, identified indicators to assess pain, and examined the impact of pain-relieving drugs. The study found that behavioral indicators can be used to determine pain, and drugs were shown to prevent pain responses. Suggestions for minimizing pain in laboratory procedures and managing pain in zebrafish were provided. This report has the potential to improve zebrafish welfare during invasive procedures in laboratories worldwide.
LABORATORY ANIMALS
(2023)
Article
Green & Sustainable Science & Technology
Shiv Mohan Singh, Masaharu Tsuji, Purnima Singh, Ravindra Uttam Mulik
Summary: The elemental composition in different Arctic fishes and invertebrates was investigated, revealing that invertebrates accumulate higher concentrations of elements than fishes, which may affect the fish community in the fragile ecosystem of the High Arctic. Most of the fishes have shown strong antifreeze protein activity.
Review
Food Science & Technology
Bertoka Fajar Surya Perwira Negara, Jae Hak Sohn, Jin-Soo Kim, Jae-Suk Choi
Summary: Phlorotannins are polyphenolic compounds found in brown seaweeds with various biological activities. Studies have shown that these compounds exhibit low toxicity in cell lines, invertebrates, microalgae, plants, animals, and humans, but research on their safety and toxicity in aquaculture fish, livestock, and companion animals is limited, highlighting the need for further investigation.
Article
Limnology
Ryan P. Bos, Shiye Zhao, Tracey T. Sutton, Tamara M. Frank
Summary: A study investigated microplastic ingestion by vertically migrating and nonmigrating mesopelagic crustaceans and fishes in the Gulf of Mexico. The results showed that 29% of crustaceans and 26% of fishes had ingested microplastics, with an average plastic length of 0.59 mm. Nonmigratory crustaceans had significantly higher levels of microplastic ingestion than migratory crustaceans, and the frequency of microplastic ingestion by nonmigratory fishes increased with depth.
LIMNOLOGY AND OCEANOGRAPHY
(2023)
Review
Biochemistry & Molecular Biology
Faiza Basheer, Poshmaal Dhar, Rasika M. Samarasinghe
Summary: Paediatric brain cancer, the second most common childhood cancer, remains a significant challenge despite advancements in treatment. Further understanding of the molecular and heterogeneity of these brain tumors using animal models is crucial for addressing long-term therapy-associated side effects.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Physiology
Sebastian Rock, Frans Rodenburg, Marcel J. M. Schaaf, Christian Tudorache
Summary: Research on stress coping style in animal welfare has gained momentum in recent years. This study analyzed the light dark challenge behavioral assay in zebrafish larvae and found that behavioral responses are robust and can be generalized for the light and dark phases. The hatching time may determine the behavioral phenotype of an individual.
FRONTIERS IN PHYSIOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Tatiana O. Kolesnikova, Konstantin A. Demin, Fabiano Costa, Konstantin N. Zabegalov, Murilo S. de Abreu, Elena Gerasimova, Allan Kalueff
Summary: Channelopathies are systemic disorders associated with dysfunctional ion channels. The zebrafish has become a popular model organism for studying these disorders, but there are still challenges to overcome.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemical Research Methods
Yushi Yang, Francesco Turci, Erika Kague, Chrissy L. Hammond, John Russo, C. Patrick Royall
Summary: In this study, the collective behavior of 50 zebrafish was investigated in a three-dimensional manner. The researchers found that the fish exhibited a transition from ordered to random behavior when they adapted to new environmental conditions. By quantifying the spatial and temporal correlation functions, the researchers identified two length scales that captured the essence of these behavioral changes. The ratio of these length scales was found to correlate with the polarization of collective motion, which was explained using a simplified model of self-propelled particles with alignment interactions.
PLOS COMPUTATIONAL BIOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Tae-Young Choi, Tae-Ik Choi, Yu-Ri Lee, Seong-Kyu Choe, Cheol-Hee Kim
Summary: Zebrafish are emerging as a powerful animal model for studying mental disorders and metabolic diseases due to their transparency, low maintenance costs, and genetic similarity to humans. Researchers highlight the importance of zebrafish in understanding communication pathways between the brain and other organs, as well as the potential for tracking metabolism and disease progression. The ease of tissue imaging, high offspring numbers, and availability of genetic techniques further contribute to the benefits of using zebrafish in biomedical research.
EXPERIMENTAL AND MOLECULAR MEDICINE
(2021)
Article
Veterinary Sciences
Maria Glaucia Carlos de Oliveira, Valeria Veras de Paula, Andressa Nunes Mouta, Isabelle de Oliveira Lima, Lua Barbalho de Macedo, Talyta Lins Nunes, Pedro Henrique Esteves Trindade, Stelio Pacca Loureiro Luna
Summary: This study validated a scale for assessing acute pain in donkeys, which showed very good intra-evaluator reliability, good to moderate inter-evaluator reliability, responsiveness for all items, good criterion validity vs. VAS, acceptable internal consistency, and an excellent accuracy for the point of rescue analgesic intervention. The scale can diagnose and quantify acute pain in donkeys submitted to castration.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Multidisciplinary Sciences
Peng Yang, Hiro Takahashi, Masataka Murase, Motoyuki Itoh
Summary: This study aimed to construct a new behavior analysis method using machine learning, which successfully identified specific behavioral features associated with electric shocks in zebrafish through 3D tracking data analysis. This method has the potential to be applied in mutant zebrafish research, drug screening, and cognitive ability tests in the future.
SCIENTIFIC REPORTS
(2021)
Review
Microbiology
Sylwia D. Tyrkalska, Sergio Candel, Annamaria Pedoto, Diana Garcia-Moreno, Francisca Alcaraz-Perez, Alvaro Sanchez-Ferrer, Maria L. Cayuela, Victoriano Mulero
Summary: Despite the recent emergence of COVID-19, research studies have already developed and utilized multiple animal models to unravel the mysteries of the disease and gain insights into the biology of SARS-CoV-2. However, there are significant challenges in studying this virus in model organisms, such as poor infectivity of clinical isolates in certain species and the lack of key features seen in COVID-19 patients. Moreover, the age-related susceptibility of severe COVID-19 poses difficulties when using young and immunologically naive laboratory animals for testing. This review discusses the animal models developed so far, highlighting the unique advantages of the zebrafish model in understanding and addressing the disease.
FEMS MICROBIOLOGY REVIEWS
(2023)
Review
Cell Biology
Shuai Li, Kok Siong Yeo, Taylor M. Levee, Cassie J. Howe, Zuag Paj Her, Shizhen Zhu
Summary: This review provides a comprehensive overview of the advantages of using zebrafish as a model for neuroblastoma research, including real-time monitoring of tumor development, robust gene manipulation, rapid assessment of genetic interactions, and cost-effective drug screening methods.
Review
Anesthesiology
Anthony J. Burand, Cheryl L. Stucky
Summary: Severe neuropathic pain is a prominent feature of Fabry disease, impacting patients' quality of life significantly. Despite existing treatment options, pain persists in many patients, with unclear understanding of the mechanisms underlying the pain.
Article
Fisheries
Eduardo Bessa, Manuela Lombardi Brandao, Eliane Goncalves-de-Freitas
Summary: Nesting is a crucial element in the reproductive repertoire of fish species, playing a role in species conservation. Fish exhibit diverse nesting behaviors, with nests serving purposes beyond spawning and parental care, such as refuge, predator avoidance, sexual selection, and social status. While beneficial for Darwinian fitness, nesting also requires time and energy investment. The evolution of nest types and functions, controlled by physiological mechanisms, is a less explored subject that can indicate the quality of aquatic environments in the changing Anthropocene world.
FISH AND FISHERIES
(2022)
Review
Fisheries
Katherine A. Sloman, Ian A. Bouyoucos, Edward J. Brooks, Lynne U. Sneddon
JOURNAL OF FISH BIOLOGY
(2019)
Article
Ecology
Stephanie M. Harris, Sebastien Descamps, Lynne U. Sneddon, Philip Bertrand, Olivier Chastel, Samantha C. Patrick
JOURNAL OF ANIMAL ECOLOGY
(2020)
Article
Biochemical Research Methods
Jack S. Thomson, All A. Al-Temeemy, Helen Isted, Joseph W. Spencer, Lynne U. Sneddon
JOURNAL OF NEUROSCIENCE METHODS
(2019)
Article
Biology
Jack S. Thomson, Anthony G. Deakin, Andrew R. Cossins, Joseph W. Spencer, Iain S. Young, Lynne U. Sneddon
JOURNAL OF EXPERIMENTAL BIOLOGY
(2020)
Article
Ecology
Daniel K. Maskrey, Lynne U. Sneddon, Kathryn E. Arnold, David C. C. Wolfenden, Jack S. Thomson
JOURNAL OF ANIMAL ECOLOGY
(2020)
Article
Biology
Stephanie M. Harris, Sebastien Descamps, Lynne U. Sneddon, Milena Cairo, Philip Bertrand, Samantha C. Patrick
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
(2020)
Review
Neurosciences
Fabiano Costa, Luiz Rosa, Vanessa A. Quadros, Murilo S. de Abreu, Adair R. S. Santos, Lynne U. Sneddon, Allan Kalueff, Denis B. Rosemberg
Summary: This article introduces the advantages of zebrafish as a pain model and its applications in studying the mechanisms of pain response. The article also discusses the latest research advances and outlines the potential advantages and limitations of zebrafish models in studying pain behaviors and mood disorders, as well as facilitating analgesic therapy screening.
CURRENT NEUROPHARMACOLOGY
(2022)
Article
Behavioral Sciences
Daniel K. Maskrey, Lynne U. Sneddon, Kathryn E. Arnold, David C. C. Wolfenden, Jack S. Thomson
Summary: Unexplained behavioural inconsistency in individual animals, termed unpredictability, can play a significant role in survival and reproduction, especially in the face of extreme environmental changes. Boldness and environmental stochasticity may influence unpredictability in animals, thus affecting their adaptability.
Correction
Behavioral Sciences
Daniel K. Maskrey, Lynne U. Sneddon, Kathryn E. Arnold, David C. C. Wolfenden, Jack S. Thomson
Article
Neurosciences
Murilo S. de Abreu, Ana C. V. V. Giacomini, Rafael Genario, Konstantin A. Demin, Tamara G. Amstislavskaya, Fabiano Costa, Denis B. Rosemberg, Lynne U. Sneddon, Tatyana Strekalova, Marta C. Soares, Allan Kalueff
Summary: Pain is critical for organismal survival, evoking strong physiological and behavioral responses in various species. However, the long-term effects of early-life pain exposure on human and animal emotional responses remain poorly understood, indicating a need for further research in this area.
NEUROSCIENCE LETTERS
(2022)
Review
Biology
Svante Winberg, Lynne Sneddon
Summary: Dominance-based social hierarchies significantly influence the behavior, physiology, and development of teleost fishes. Fights for social dominance are influenced by heritable factors and previous social experience, with individuals displaying a proactive coping style having an advantage. Agonistic behavior is controlled by the brain's social decision-making network and its monoaminergic systems.
JOURNAL OF EXPERIMENTAL BIOLOGY
(2022)
Article
Biology
Tzu-Hsin Kuo, Lynne U. Sneddon, Joseph W. Spencer, Chuan-Chin Chiao
Summary: This study used acetic acid to stimulate cuttlefish and found that it caused an increase in grooming behavior in cuttlefish. Additionally, the injection of lidocaine reduced grooming behaviors in acetic-acid-injected cuttlefish. This suggests that cuttlefish are aware of their injuries and pain, and pain-relieving drugs should be considered when subjecting them to painful treatments in the laboratory.
Review
Biology
Guiomar Rotllant, Pol Llonch, Jose A. Garcia del Arco, Oscar Chic, Paul Flecknell, Lynne U. Sneddon
Summary: Animals that can feel pain and distress, such as decapod crustaceans, should be protected in situations that could cause suffering, like experimental surgery or killing for human consumption. Recent studies have shown that decapods have a pain-like experience, leading the UK government and other countries to recognize them as sentient beings and enforce guidelines for their treatment during slaughter. This review presents various drugs and methods for anesthesia and analgesia in a wide range of crustacean species, providing a valuable tool for researchers and stakeholders to ensure the welfare of these animals.
Article
Fisheries
Anthony G. Deakin, Joseph W. Spencer, Andrew R. Cossins, Iain S. Young, Lynne U. Sneddon