Targeted myocardial delivery of GDF11 gene rejuvenates the aged mouse heart and enhances myocardial regeneration after ischemia–reperfusion injury

Notch activation enhances lineage commitment and protective signaling in cardiac progenitor cells

(2015) Natalie Gude et al.   BASIC RESEARCH IN CARDIOLOGY

GDF11 Increases with Age and Inhibits Skeletal Muscle Regeneration

(2015) Marc A. Egerman et al.   Cell Metabolism

Circulating Growth Differentiation Factor 11/8 Levels Decline With AgeNovelty and Significance

(2015) Tommaso Poggioli et al.   CIRCULATION RESEARCH

GDF11 Does Not Rescue Aging-Related Pathological HypertrophyNovelty and Significance

(2015) Shavonn C. Smith et al.   CIRCULATION RESEARCH

Reduced Circulating GDF11 Is Unlikely Responsible for Age-Dependent Changes in Mouse Heart, Muscle, and Brain

(2015) Buel D. Rodgers et al.   ENDOCRINOLOGY

Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice

(2014) Saul A Villeda et al.   NATURE MEDICINE

Transforming growth factor-β superfamily ligand trap ACE-536 corrects anemia by promoting late-stage erythropoiesis

(2014) Rajasekhar N V S Suragani et al.   NATURE MEDICINE

Young Blood

(2014) Alessandro Laviano   NEW ENGLAND JOURNAL OF MEDICINE

Vascular and Neurogenic Rejuvenation of the Aging Mouse Brain by Young Systemic Factors

(2014) L. Katsimpardi et al.   SCIENCE

Restoring Systemic GDF11 Levels Reverses Age-Related Dysfunction in Mouse Skeletal Muscle

(2014) M. Sinha et al.   SCIENCE

Doxorubicin induces senescence and impairs function of human cardiac progenitor cells

(2013) Elena Piegari et al.   BASIC RESEARCH IN CARDIOLOGY

Growth Differentiation Factor 11 Is a Circulating Factor that Reverses Age-Related Cardiac Hypertrophy

(2013) Francesco S. Loffredo et al.   CELL

The use of cationic microbubbles to improve ultrasound-targeted gene delivery to the ischemic myocardium

(2012) Lu Sun et al.   BIOMATERIALS

Microbubbles as a Vehicle for Gene and Drug Delivery: Current Clinical Implications and Future Perspectives

(2012) Nicolas Geis et al.   CURRENT PHARMACEUTICAL DESIGN

Reconstitution of aged bone marrow with young cells repopulates cardiac-resident bone marrow-derived progenitor cells and prevents cardiac dysfunction after a myocardial infarction

(2012) Shu-Hong Li et al.   EUROPEAN HEART JOURNAL

Effects of Age and Heart Failure on Human Cardiac Stem Cell Function

(2011) Daniela Cesselli et al.   AMERICAN JOURNAL OF PATHOLOGY

Repeated and targeted transfer of angiogenic plasmids into the infarcted rat heart via ultrasound targeted microbubble destruction enhances cardiac repair

(2011) Hiroko Fujii et al.   EUROPEAN HEART JOURNAL

Myocyte Turnover in the Aging Human Heart

(2010) Jan Kajstura et al.   CIRCULATION RESEARCH

Clonality of mouse and human cardiomyogenesis in vivo

(2009) T. Hosoda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ultrasound-Targeted Gene Delivery Induces Angiogenesis After a Myocardial Infarction in Mice

(2009) Hiroko Fujii et al.   JACC-Cardiovascular Imaging

Activation of Cardiac Progenitor Cells Reverses the Failing Heart Senescent Phenotype and Prolongs Lifespan

(2008) Arantxa Gonzalez et al.   CIRCULATION RESEARCH