Unacylated ghrelin analog prevents myocardial reperfusion injury independently of permeability transition pore

Studies on the role of apoptosis after transient myocardial ischemia: genetic deletion of the executioner caspases-3 and -7 does not limit infarct size and ventricular remodeling

(2016) Javier Inserte et al.   BASIC RESEARCH IN CARDIOLOGY

Evolving Therapies for Myocardial Ischemia/Reperfusion Injury

(2015) Borja Ibáñez et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Cyclosporine before PCI in Patients with Acute Myocardial Infarction

(2015) Thien-Tri Cung et al.   NEW ENGLAND JOURNAL OF MEDICINE

Unacylated ghrelin restores insulin and autophagic signaling in skeletal muscle of diabetic mice

(2015) Bjorn T. Tam et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Protective effects of desacyl ghrelin on diabetic cardiomyopathy

(2014) Xiao M. Pei et al.   ACTA DIABETOLOGICA

Unacylated Ghrelin Induces Oxidative Stress Resistance in a Glucose Intolerance and Peripheral Artery Disease Mouse Model by Restoring Endothelial Cell miR-126 Expression

(2014) Gabriele Togliatto et al.   DIABETES

Determinants of improved one-year survival in non-ST-segment elevation myocardial infarction patients: Insights from the French FAST-MI program over 15years

(2014) Etienne Puymirat et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Cardiac fibroblasts protect cardiomyocytes against lethal ischemia–reperfusion injury

(2014) Maryline Abrial et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Pro-Substance P for Evaluation of Risk in Acute Myocardial Infarction

(2014) Leong L. Ng et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Des-acyl ghrelin protects microvascular endothelial cells from oxidative stress-induced apoptosis through sirtuin 1 signaling pathway

(2014) Takeshi Shimada et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Unacylated Ghrelin Suppresses Ghrelin-Induced Neuronal Activity in the Hypothalamus and Brainstem of Male Rats

(2014) Darko M. Stevanovic et al.   PLoS One

Desacyl ghrelin prevents doxorubicin-induced myocardial fibrosis and apoptosis via the GHSR-independent pathway

(2013) Xiao M. Pei et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Does des-acyl ghrelin improve glycemic control in obese diabetic subjects by decreasing acylated ghrelin levels?

(2013) Behiye Özcan et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Des-acyl ghrelin analogs prevent high-fat-diet-induced dysregulation of glucose homeostasis

(2013) Patric J. D. Delhanty et al.   FASEB JOURNAL

Activation of cGMP/Protein Kinase G Pathway in Postconditioned Myocardium Depends on Reduced Oxidative Stress and Preserved Endothelial Nitric Oxide Synthase Coupling

(2013) Javier Inserte et al.   Journal of the American Heart Association

The ghrelin gene products and exendin-4 promote survival of human pancreatic islet endothelial cells in hyperglycaemic conditions, through phosphoinositide 3-kinase/Akt, extracellular signal-related kinase (ERK)1/2 and cAMP/protein kinase A (PKA) signalling pathways

(2012) E. Favaro et al.   DIABETOLOGIA

Metabolic effects of overnight continuous infusion of unacylated ghrelin in humans

(2012) A. Benso et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

In vitro and in vivo stability and pharmacokinetic profile of unacylated ghrelin (UAG) analogues

(2012) Michel Julien et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Des-Acyl Ghrelin Fragments and Analogues Promote Survival of Pancreatic β-Cells and Human Pancreatic Islets and Prevent Diabetes in Streptozotocin-Treated Rats

(2012) Riccarda Granata et al.   JOURNAL OF MEDICINAL CHEMISTRY

Rapamycin protects against myocardial ischemia–reperfusion injury through JAK2–STAT3 signaling pathway

(2012) Anindita Das et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Opposite and tissue-specific effects of coenzyme Q2 on mPTP opening and ROS production between heart and liver mitochondria: Role of complex I

(2012) Abdallah Gharib et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Synergistic protective effect of cyclosporin A and rotenone against hypoxia–reoxygenation in cardiomyocytes

(2012) Geoffrey Teixeira et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Caspase-3 Protects Stressed Organs against Cell Death

(2012) H. Khalil et al.   MOLECULAR AND CELLULAR BIOLOGY

mTOR-Dependent Cell Survival Mechanisms

(2012) C.-M. Hung et al.   Cold Spring Harbor Perspectives in Biology

Differential Roles of GSK-3β During Myocardial Ischemia and Ischemia/Reperfusion

(2011) Peiyong Zhai et al.   CIRCULATION RESEARCH

Unacylated Ghrelin Rescues Endothelial Progenitor Cell Function in Individuals With Type 2 Diabetes

(2010) G. Togliatto et al.   DIABETES

Des-Acyl Ghrelin Has Specific Binding Sites and Different Metabolic Effects from Ghrelin in Cardiomyocytes

(2010) Pamela V. Lear et al.   ENDOCRINOLOGY

MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice

(2010) Denghong Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

Assessment of myocardial ischemia and viability using tissue Doppler and deformation imaging: the lessons from the experimental studies

(2009) H. Thibault et al.   Archives of Cardiovascular Diseases

Neuroprotective Effect of Ghrelin Is Associated with Decreased Expression of Prostate Apoptosis Response-4

(2009) Sunyoung HWANG et al.   ENDOCRINE JOURNAL

Delayed recovery of intracellular acidosis during reperfusion prevents calpain activation and determines protection in postconditioned myocardium

(2008) J. Inserte et al.   CARDIOVASCULAR RESEARCH

Phosphatidylinositol-3-kinase/Akt/glycogen synthase kinase-3β and ERK1/2 pathways mediate protective effects of acylated and unacylated ghrelin against oxygen–glucose deprivation-induced apoptosis in primary rat cortical neuronal cells

(2008) Hyunju Chung et al.   JOURNAL OF ENDOCRINOLOGY

Desacyl ghrelin inhibits the orexigenic effect of peripherally injected ghrelin in rats

(2008) Tobias Inhoff et al.   PEPTIDES