Article
Medicine, General & Internal
Tobias F. S. Pustjens, Marijke J. C. Timmermans, Saman Rasoul, Arnoud W. J. van't Hof
Summary: The study found that NSTE-ACS patients with MVD undergoing MV-PCI and CO-PCI had similar mortality rates at long-term follow-up, but the MV-PCI group showed improved event-free survival in terms of fewer coronary reinterventions.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Guilherme Pinheiro Machado, Andre Luiz Theobald, Gustavo Neves de Araujo, Anderson Donelli da Silveira, Rodrigo Vugman Wainstein, Julia Fagundes Fracasso, Matheus Niches, Angelo Chies, Sandro Cadaval Goncalves, Mauricio Pimentel, Marco Vugman Wainstein
Summary: This study investigated the incidence and outcomes of pre-percutaneous coronary intervention (PCI) sudden cardiac arrest (SCA) in patients admitted with ST-segment elevation myocardial infarction (STEMI). The study found that pre-PCI SCA was associated with higher in-hospital mortality.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Medicine, General & Internal
Erol Gursoy, Onur Baydar
Summary: The study investigates the correlation between TyG index and contrast induced nephropathy (CIN) in non-diabetic patients with non-ST elevation myocardial infarction (NSTEMI) undergoing percutaneous coronary intervention (PCI). The results show that higher TyG indexes are associated with an increased risk of CIN in non-diabetic patients with NSTEMI. TyG index, age, and glomerular filtration rate are identified as independent risk factors for CIN.
Article
Cardiac & Cardiovascular Systems
Qu-Cheng Wei, Yu-wen Chen, Qi-Yue Gao, Kai-Da Ren, Ya-Bin Liu, Fan He, Jia-Tong Shi, Jun Jiang
Summary: Several markers of stress hyperglycemia, such as admission blood glucose, fasting blood sugar, and stress hyperglycemia ratio, were investigated for their potential associations with adverse cardiovascular events in STEMI patients who underwent PCI. Stress hyperglycemia was found to be significantly associated with an increased risk of in-hospital death and all-cause mortality.
CARDIOVASCULAR DIABETOLOGY
(2023)
Article
Multidisciplinary Sciences
Jangho Park, Sangwoo Park, Yong-Giun Kim, Soe Hee Ann, Hyun Woo Park, Jon Suh, Jae-Hyung Roh, Young-Rak Cho, Seungbong Han, Gyung-Min Park
Summary: An analysis of National Health Insurance data in Korea showed that pre-existing depression does not have a significant impact on mortality in patients with established coronary artery disease undergoing PCI. However, younger patients with angina and depression may have a higher risk of all-cause mortality.
SCIENTIFIC REPORTS
(2021)
Article
Endocrinology & Metabolism
Xiao-Fang Tang, Chen He, Pei Zhu, Che Zhang, Ying Song, Jing-Jing Xu, Yi Yao, Na Xu, Ping Jiang, Lin Jiang, Zhan Gao, Xue-yan Zhao, Li-jian Gao, Lei Song, Yue-Jin Yang, Run-Lin Gao, Bo Xu, Jin-Qing Yuan
Summary: The study found that hyperuricemia is associated with higher risks of 2- and 5-year all-cause deaths in patients with STEMI undergoing PCI. However, no correlation was found between hyperuricemia and inflammatory responses in newly admitted STEMI patients.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Review
Cardiac & Cardiovascular Systems
Joyce Lim, Allan Davies, Stephen Brienesse, Nishani S. Mabotuwana, Andrew Boyle
Summary: This systematic review investigates the association between leukocyte response and outcomes in patients with STEMI. The findings suggest that leukocyte count is associated with the occurrence of MACE within 30 days and 1 year. However, the high heterogeneity among studies limits the generalizability of these findings and further research is needed.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Jamshid Bagheri, Mana Jameie, Zahra Dehghani Saryazdi, Arash Jalali, Malihe Rezaee, Mina Pashang, Afsaneh Aein, Kaveh Hosseini, Seyed Hossein Ahmadi Tafti, Amin Bagheri
Summary: This study found that PPCI did not increase the risk of in-hospital mortality, LOS, or bleeding among patients with acute STEMI who underwent CABG. However, some PPCI subgroups, especially those with complicated PPCI, were at increased risk.
HEART LUNG AND CIRCULATION
(2023)
Article
Cardiac & Cardiovascular Systems
Pernille Gro Thrane, Kevin Kris Warnakula Olesen, Troels Thim, Christine Gyldenkerne, Martin Bodtker Mortensen, Steen Dalby Kristensen, Michael Maeng
Summary: In Western Denmark, the implementation of primary percutaneous coronary intervention (pPCI) for ST-segment elevation myocardial infarction (STEMI) has led to a significant reduction in 1-year mortality, with the greatest decline occurring within the first 30 days after pPCI. This highlights the importance of optimizing early management for improving overall survival in STEMI patients.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Tomasz Tokarek, Artur Dziewierz, Krzysztof Plens, Tomasz Rakowski, Anna Jaroszynska, Stanislaw Bartus, Zbigniew Siudak
Summary: This study aimed to assess the clinical outcomes of patients with STEMI treated with PCI during on- and off-hours of work. The results suggest that PCIs performed during off-hours may be associated with a higher rate of periprocedural mortality and higher radiation doses.
HELLENIC JOURNAL OF CARDIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Chao Wu, Xiaojin Gao, Ling Li, Quanmin Jing, Weimin Li, Haiyan Xu, Wenbo Zhang, Sidong Li, Yanyan Zhao, Yang Wang, Wei Li, Yongjian Wu, Fenghuan Hu, Chen Jin, Shubin Qiao, Jingang Yang, Yuejin Yang
Summary: This study evaluated the role of ST-segment resolution (STR) and Thrombolysis in Myocardial Infarction (TIMI) flow in reperfusion evaluation after primary percutaneous coronary intervention (PPCI) for ST-segment-elevation myocardial infarction. The results showed that STR =50% and complete STR were significantly associated with lower 2-year mortality compared to STR <50%. Additionally, the combination of STR and TIMI flow provided incremental prognostic information beyond either measure alone.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Physiology
Yuhui Lin, Wenjun Dai, Yongquan Chen, Xiaoqing He, Yunhong Xu
Summary: This study evaluated the value of neutrophil-to-platelet ratio (NPR) in predicting all-cause mortality in patients with ST-elevation myocardial infarction (STEMI) after primary percutaneous coronary intervention (PCI). The results showed that NPR could predict all-cause death in patients with STEMI after primary PCI, suggesting its potential application in risk stratification and individualized treatment.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Medicine, General & Internal
Muhsin Kalyoncuoglu, Fahrettin Katkat, Halil Ibrahim Biter, Sinem Cakal, Aydin Rodi Tosu, Mehmet Mustafa Can
Summary: This study evaluated the impact of CONUT, PNI, and GNRI scores on major outcomes in elderly NSTEMI patients, finding that malnourished patients had more MACCEs at 1-year follow-up. The CONUT score independently predicted MACCEs and had significantly superior discriminative power compared to PNI and GNRI.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Samian Sulaiman, Akram Kawsara, Mohamed O. Mohamed, Harriette G. C. Van Spall, Nadia Sutton, David R. Holmes, Mamas A. Mamas, Mohamad Alkhouli
Summary: The study found that women are less likely to receive primary percutaneous coronary intervention (pPCI) than men. However, the reduction in in-hospital mortality with pPCI is comparable between men and women. Despite this, the rates of pPCI remain lower in women in contemporary US practice.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Cardiac & Cardiovascular Systems
Jaihoon Amon, Graham C. Wong, Terry Lee, Joel Singer, John Cairns, Jay S. Shavadia, Christopher Granger, Kenneth Gin, Tracy Y. Wang, Sean van Diepen, Christopher B. Fordyce
Summary: The aim of this study was to identify factors associated with in-hospital adverse events in stable patients with STEMI who received pPCI. The results showed that only 1 in 20 stable STEMI patients developed an adverse event after receiving pPCI. Moderate to severe chronic kidney disease was identified as a predictor of future adverse events.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Article
Cardiac & Cardiovascular Systems
Isabelle Durand-Zaleski, Gregory Ducrocq, Maroua Mimouni, Jerome Frenkiel, Cristina Avendano-Sola, Jose R. Gonzalez-Juanatey, Emile Ferrari, Gilles Lemesle, Etienne Puymirat, Laurence Berard, Marine Cachanado, Joan Albert Arnaiz, Manuel Martinez-Selles, Johanne Silvain, Albert Ariza-Sole, Gonzalo Calvo, Nicolas Danchin, Sandra Paco, Elodie Drouet, Helene Abergel, Alexandra Rousseau, Tabassome Simon, Philippe Gabriel Steg
Summary: This study assessed the cost-effectiveness and cost-utility ratios of restrictive vs. liberal transfusion strategy in acute myocardial infarction patients. The results showed that the restrictive strategy was dominant at 30 days, saving costs and improving outcomes, but it no longer maintained non-inferiority on MACE at 1 year.
EUROPEAN HEART JOURNAL-QUALITY OF CARE AND CLINICAL OUTCOMES
(2023)
Article
Cardiac & Cardiovascular Systems
Michel Zeitouni, David Sulman, Johanne Silvain, Mathieu Kerneis, Paul Guedeney, Olivier Barthelemy, Delphine Brugier, Pierre Sabouret, Niki Procopi, Jean-Philippe Collet, Gilles Montalescot
Summary: The 2021 ESC guidelines significantly improved the detection of young individuals before their first STEMI compared to previous ESC guidelines. In secondary prevention, most young individuals did not reach the recommended low-density lipoprotein cholesterol levels, but only one quarter would be eligible for PCSK9i treatment.
Article
Pediatrics
Noel Peretti, Alexandre Vimont, Emmanuel Mas, Jean Ferrieres, Patrick Tounian, Julie Lemale, Franck Boccara, Mathilde Di Filippo, Sybil Charriere, Philippe Moulin, Pierre Poinsot, Yves Cottin, Pierre-Henri Ducluzeau, Caroline Dourmap, Bertrand Cariou, Michel Farnier, Francois Paillard, Alain Pradignac, Cecile Yelnik, Antonio Gallo, Eric Bruckert, Sophie Beliard
Summary: Childhood and parental factors, including genetic diagnosis and parental vascular disease, are associated with the initiation of statin therapy in children with HeFH. Genetic diagnosis may be useful for cardiovascular prevention in children.
JOURNAL OF PEDIATRICS
(2023)
Article
Cardiac & Cardiovascular Systems
Johanne Silvain, Guillaume Cayla, Emile Ferrari, Gregoire Range, Etienne Puymirat, Nicolas Delarche, Jean-Philippe Collet, Raphaelle Dumaine, Michel Slama, Laurent Payot, Mohamad E. Kasty, Karim Aacha, Eric Vicaut, Gilles Montalescot
Summary: The ABYSS trial aims to evaluate the cardiovascular safety of continuing β-blocker therapy in stable post-MI patients without heart failure and preserved LVEF.
AMERICAN HEART JOURNAL
(2023)
Article
Cardiac & Cardiovascular Systems
Francesco Costa, Claudio Montalto, Mattia Branca, Sung-Jin Hong, Hirotoshi Watanabe, Anna Franzone, Pascal Vranckx, Joo-Yong Hahn, Hyeon-Cheol Gwon, Fausto Feres, Yangsoo Jang, Giuseppe De Luca, Elvin Kedhi, Davide Cao, Philippe Gabriel Steg, Deepak L. Bhatt, Gregg W. Stone, Antonio Micari, Stephan Windecker, Takeshi Kimura, Myeong-Ki Hong, Roxana Mehran, Marco Valgimigli
Summary: The study evaluated the impact of an abbreviated dual antiplatelet therapy (DAPT) regimen in high bleeding risk patients after percutaneous coronary intervention (PCI), using existing evidence. It found that a shorter DAPT duration (1-3 months) reduced bleeding and cardiovascular mortality without increasing ischemic events in these patients.
EUROPEAN HEART JOURNAL
(2023)
Article
Cardiac & Cardiovascular Systems
Emmanuelle Vidal-Petiot, Yedid Elbez, Jules Mesnier, Gregory Ducrocq, Ian Ford, Michal Tendera, Roberto Ferrari, Jean-Claude Tardif, Kim M. Fox, Philippe Gabriel Steg
Summary: This study compared the benefits of strict vs. standard control of blood pressure with the potential benefits of controlling other modifiable risk factors in patients with chronic coronary syndromes. The results showed that the benefit associated with strict blood pressure control was marginal and driven only by the diastolic component, while uncontrolled other risk factors were associated with a gradually increasing risk. Therefore, optimizing other risk factors should be prioritized over further reduction of systolic blood pressure. The optimal blood pressure target in chronic coronary syndromes may be <=139/79 mmHg.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Guillaume Marquis-Gravel, Laurie-Anne Boivin-Proulx, Zhen Huang, Steven L. Zelenkofske, A. Michael Lincoff, Roxana Mehran, P. Gabriel Steg, Christoph Bode, John H. Alexander, Thomas J. Povsic
Summary: This study compared the effectiveness of vascular closure devices (VCDs) with manual compression in reducing bleeding after transfemoral percutaneous coronary intervention. The results showed that there was no significant difference in bleeding rate between the two groups, but the VCD group had shorter recovery time. Further investigation is needed for high-bleeding risk populations.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Cardiac & Cardiovascular Systems
Victoria Gauthier, Martin Lafrance, Mael Barthoulot, Louis Rousselet, Michele Montaye, Jean Ferrieres, Samantha Huo Yung Kai, Katia Biasch, Marie Moitry, Philippe Amouyel, Jean Dallongeville, Aline Meirhaeghe
Summary: The study aimed to characterize the long-term risk of first recurrence of ACS among survivors of an incident ACS, based on the STEMI/NSTEMI/UA diagnosis. The risk of recurrence did not depend on the type of the incident ACS, but major complications and impaired LVEF increased the risk. The most frequent forms of recurrence were NSTEMI and UA.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Article
Pharmacology & Pharmacy
William A. E. Parker, Dominick J. Angiolillo, Fabiana Rollini, Francesco Franchi, Marc P. Bonaca, Deepak L. Bhatt, Ph. Gabriel Steg, Rachel C. Orme, Mark R. Thomas, Heather M. Judge, Marc S. Sabatine, Robert F. Storey
Summary: This study investigated the influence of body mass on the response to ticagrelor treatment in patients with chronic coronary syndromes. The results showed that body weight was positively correlated with P2Y12 reactivity units before drug administration, but not after. The dosage of 60 mg ticagrelor was significantly correlated with body mass index. However, body mass did not affect the chance of high platelet reactivity. Overall, the currently-used regimens are adequate across different body weights and body mass index in this patient population.
VASCULAR PHARMACOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Brian Olshansky, Deepak L. L. Bhatt, Michael Miller, Ph. Gabriel Steg, Eliot A. A. Brinton, Terry A. A. Jacobson, Steven B. B. Ketchum, Ralph T. T. Doyle Jr, Rebecca A. A. Juliano, Lixia Jiao, Peter R. R. Kowey, James A. A. Reiffel, Jean-Claude Tardif, Christie M. M. Ballantyne, Mina K. K. Chung
Summary: In the REDUCE-IT study, icosapent ethyl (IPE) reduced cardiovascular events but was associated with increased atrial fibrillation/atrial flutter (AF) hospitalization. The study analyzed the relationships between IPE and outcomes in patients with or without prior AF and with or without in-study AF hospitalization. Overall, in-study AF hospitalization rates were higher in patients with prior AF, especially in those randomized to IPE. Serious bleeding rates also trended higher in these patients. However, patients with prior AF or in-study AF hospitalization showed consistent risk reductions in cardiovascular events with IPE.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Health Care Sciences & Services
Jean Ferrieres, Eric Bruckert, Michel Farnier, Michel Krempf, Jean-Jacques Mourad, Baptiste Roux, Francois Schiele
Summary: This online survey studied French cardiologists' lipid-lowering approaches in patients with hypercholesterolemia and high cardiovascular risk. The results showed that most physicians underestimated the cardiovascular risk and selected higher-than-recommended LDL-C targets and less intensive treatment.
JOURNAL OF COMPARATIVE EFFECTIVENESS RESEARCH
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Maroua Mimouni, Julie Bulsei, Meryl Darlington, Candice Estellat, Francois Rouzet, Fabien Hyafil, Isabelle Durand-Zaleski
Summary: This study evaluated the cost-effectiveness of Rb-PET-MPI compared to Tc-SPECT-MPI for detecting myocardial ischemia, and the results showed that Rb-PET-MPI was a cost-saving and outcome-improving option for patients with PTP > 15%.
Article
Cardiac & Cardiovascular Systems
Paul Guedeney, Julio Farjat-Pasos, Gabriel Asslo, Vincent Roule, Farzin Beygui, Alexis Hermida, Paul Gabrion, Laurent Leborgne, Christine Houde, Florent Huang, Benoit Lattuca, Florence Leclercq, Jules Mesnier, Jeremie Abtan, Stephanie Rouanet, Nadjib Hammoudi, Jean-Philippe Collet, Michel Zeitouni, Johanne Silvain, Gilles Montalescot, Josep Rodes-Cabau
Summary: This study aimed to evaluate the outcomes of patients undergoing patent foramen ovale (PFO) closure with two different antiplatelet strategies (single antiplatelet therapy [SAPT] and temporary dual antiplatelet therapy [DAPT]). The results showed that both treatment strategies had similar clinical outcomes, highlighting the lack of benefit of temporary DAPT in this setting.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR PHARMACOTHERAPY
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Christopher W. Baugh, Yonathan Freund, Philippe Gabriel Steg, Richard Body, David J. Maron, Maame Yaa A. B. Yiadom
Summary: Emergency department (ED) crowding is a global problem caused by hospital capacity and other health system challenges. Patients with cardiovascular emergencies are particularly vulnerable due to the crowding, which may lead to avoidance of the ED, premature departure, or delays in receiving care. This paper discusses the causes of crowding, its impact on cardiovascular emergencies, and potential solutions.
EUROPEAN HEART JOURNAL-ACUTE CARDIOVASCULAR CARE
(2023)
Letter
Cardiac & Cardiovascular Systems
Shaun G. Goodman, Philippe Gabriel Steg, Yann Poulouin, Deepak L. Bhatt, Vera A. Bittner, Rafael Diaz, Genevieve Garon, Robert A. Harrington, J. Wouter Jukema, Garen Manvelian, Wanda Stipek, Michael Szarek, Harvey D. White, Gregory G. Schwartz
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)