Coding and non-coding variants in the SHOX2 gene in patients with early-onset atrial fibrillation

A common Shox2-Nkx2-5 antagonistic mechanism primes the pacemaker cell fate in the pulmonary vein myocardium and sinoatrial node

(2015) W. Ye et al.   DEVELOPMENT

Integrating Genetic, Transcriptional, and Functional Analyses to Identify 5 Novel Genes for Atrial Fibrillation

(2014) Moritz F. Sinner et al.   CIRCULATION

Emerging Directions in the Genetics of Atrial Fibrillation

(2014) Nathan R. Tucker et al.   CIRCULATION RESEARCH

Cellular and Molecular Electrophysiology of Atrial Fibrillation Initiation, Maintenance, and Progression

(2014) Jordi Heijman et al.   CIRCULATION RESEARCH

The Clinical Profile and Pathophysiology of Atrial Fibrillation

(2014) Jason Andrade et al.   CIRCULATION RESEARCH

Sinoatrial node electrical activity modulates pulmonary vein arrhythmogenesis

(2014) Yao-Chang Chen et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Assessing the ceRNA Hypothesis with Quantitative Measurements of miRNA and Target Abundance

(2014) Rémy Denzler et al.   MOLECULAR CELL

Atrial fibrillation and microRNAs

(2014) Gaetano Santulli et al.   Frontiers in Physiology

Islet1 is a direct transcriptional target of the homeodomain transcription factor Shox2 and rescues the Shox2-mediated bradycardia

(2013) Sandra Hoffmann et al.   BASIC RESEARCH IN CARDIOLOGY

Transcription factors and atrial fibrillation

(2013) S. Mahida   CARDIOVASCULAR RESEARCH

MicroRNA29

(2013) Kristin Dawson et al.   CIRCULATION

Identification of heart rate–associated loci and their effects on cardiac conduction and rhythm disorders

(2013) Marcel den Hoed et al.   NATURE GENETICS

Diversifying microRNA sequence and function

(2013) Stefan L. Ameres et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Circulating MicroRNAs

(2012) Esther E. Creemers et al.   CIRCULATION RESEARCH

miR-92b regulates Mef2 levels through a negative-feedback circuit during Drosophila muscle development

(2012) Z. Chen et al.   DEVELOPMENT

Regulation of zebrafish heart regeneration by miR-133

(2012) Viravuth P. Yin et al.   DEVELOPMENTAL BIOLOGY

Molekulare Mechanismen von Vorhofflimmern

(2012) R. Wakili et al.   HERZ

Meta-analysis identifies six new susceptibility loci for atrial fibrillation

(2012) Patrick T Ellinor et al.   NATURE GENETICS

The Role of Shox2 in SAN Development and Function

(2012) Hongbing Liu et al.   PEDIATRIC CARDIOLOGY

Protein Kinase D2 Controls Cardiac Valve Formation in Zebrafish by Regulating Histone Deacetylase 5 Activity

(2011) Steffen Just et al.   CIRCULATION

PITX2c Is Expressed in the Adult Left Atrium, and Reducing Pitx2c Expression Promotes Atrial Fibrillation Inducibility and Complex Changes in Gene Expression

(2011) Paulus Kirchhof et al.   Circulation-Cardiovascular Genetics

Variants in the 3′ untranslated region of the KCNQ1-encoded Kv7.1 potassium channel modify disease severity in patients with type 1 long QT syndrome in an allele-specific manner

(2011) Ahmad S. Amin et al.   EUROPEAN HEART JOURNAL

Serum levels of microRNAs in patients with heart failure

(2011) Yaron Goren et al.   EUROPEAN JOURNAL OF HEART FAILURE

Functional Redundancy between HumanSHOXand MouseShox2Genes in the Regulation of Sinoatrial Node Formation and Pacemaking Function

(2011) Hongbing Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNAs and atrial fibrillation: new fundamentals

(2010) Z. Wang et al.   CARDIOVASCULAR RESEARCH

Monogenic atrial fibrillation as pathophysiological paradigms

(2010) S. Mahida et al.   CARDIOVASCULAR RESEARCH

Gene expression profiling in whole blood of patients with coronary artery disease

(2010) Chiara Taurino et al.   CLINICAL SCIENCE

MicroRNA Regulatory Networks in Cardiovascular Development

(2010) Ning Liu et al.   DEVELOPMENTAL CELL

Shox2 mediates Tbx5 activity by regulating Bmp4 in the pacemaker region of the developing heart

(2010) Sandra Puskaric et al.   HUMAN MOLECULAR GENETICS

Several common variants modulate heart rate, PR interval and QRS duration

(2010) Hilma Holm et al.   NATURE GENETICS

Genome-wide association study of PR interval

(2010) Arne Pfeufer et al.   NATURE GENETICS

Pitx2 prevents susceptibility to atrial arrhythmias by inhibiting left-sided pacemaker specification

(2010) J. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Shox2 is essential for the differentiation of cardiac pacemaker cells by repressing Nkx2-5

(2009) Ramón A. Espinoza-Lewis et al.   DEVELOPMENTAL BIOLOGY

Large scale replication and meta-analysis of variants on chromosome 4q25 associated with atrial fibrillation

(2009) S. Kaab et al.   EUROPEAN HEART JOURNAL

Long-term Outcomes in Individuals With Prolonged PR Interval or First-Degree Atrioventricular Block

(2009) Susan Cheng   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

First evidence for an association of a functional variant in the microRNA-510 target site of the serotonin receptor-type 3E gene with diarrhea predominant irritable bowel syndrome

(2008) Johannes Kapeller et al.   HUMAN MOLECULAR GENETICS