The Role of Shox2 in SAN Development and Function

Ectopic expression of Nkx2.5 suppresses the formation of the sinoatrial node in mice

(2011) Ramón A. Espinoza-Lewis et al.   DEVELOPMENTAL BIOLOGY

Functional Redundancy between HumanSHOXand MouseShox2Genes in the Regulation of Sinoatrial Node Formation and Pacemaking Function

(2011) Hongbing Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Development of the Pacemaker Tissues of the Heart

(2010) Vincent M. Christoffels et al.   CIRCULATION RESEARCH

Shox2 mediates Tbx5 activity by regulating Bmp4 in the pacemaker region of the developing heart

(2010) Sandra Puskaric et al.   HUMAN MOLECULAR GENETICS

Pitx2 prevents susceptibility to atrial arrhythmias by inhibiting left-sided pacemaker specification

(2010) J. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Shox2 is essential for the differentiation of cardiac pacemaker cells by repressing Nkx2-5

(2009) Ramón A. Espinoza-Lewis et al.   DEVELOPMENTAL BIOLOGY

If Inhibition with Ivabradine

(2009) Irina Savelieva et al.   DRUG SAFETY

Formation of the Sinus Node Head and Differentiation of Sinus Node Myocardium Are Independently Regulated by Tbx18 and Tbx3

(2008) Cornelia Wiese et al.   CIRCULATION RESEARCH

Shox2-deficiency leads to dysplasia and ankylosis of the temporomandibular joint in mice

(2008) Shuping Gu et al.   MECHANISMS OF DEVELOPMENT