A Novel Model of P-Glycoprotein Inhibitor Screening Using Human Small Intestinal Organoids

Measurement of Rhodamine 123 in Three-Dimensional Organoids: A Novel Model for P-Glycoprotein Inhibitor Screening

(2016) Yuanjin Zhang et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Drug–protein hydrogen bonds govern the inhibition of the ATP hydrolysis of the multidrug transporter P-glycoprotein

(2016) Eduardo E. Chufan et al.   BIOCHEMICAL PHARMACOLOGY

Optimization by Molecular Fine Tuning of Dihydro-β-agarofuran Sesquiterpenoids as Reversers of P-Glycoprotein-Mediated Multidrug Resistance

(2016) Oliver Callies et al.   JOURNAL OF MEDICINAL CHEMISTRY

In vitro and in vivo evaluations of the P-glycoprotein-mediated efflux of dibenzoylhydrazines

(2016) Ken-ichi Miyata et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

P-glycoprotein in autoimmune rheumatic diseases

(2015) M. García-Carrasco et al.   AUTOIMMUNITY REVIEWS

P-glycoprotein interactions of novel psychoactive substances – Stimulation of ATP consumption and transport across Caco-2 monolayers

(2015) Markus R. Meyer et al.   BIOCHEMICAL PHARMACOLOGY

In vitroeffects of standardized extract ofBacopa monnieraand its five individual active constituents on human P-glycoprotein activity

(2015) Rajbir Singh et al.   XENOBIOTICA

SAR Studies on Tetrahydroisoquinoline Derivatives: The Role of Flexibility and Bioisosterism To Raise Potency and Selectivity toward P-glycoprotein

(2014) Elena Capparelli et al.   JOURNAL OF MEDICINAL CHEMISTRY

Stereoselective Property of 20(S)-Protopanaxadiol Ocotillol Type Epimers Affects Its Absorption and Also the Inhibition of P-Glycoprotein

(2014) Wenyan Wang et al.   PLoS One

Development of an Improved Three-Dimensional In Vitro Intestinal Mucosa Model for Drug Absorption Evaluation

(2013) Na Li et al.   TISSUE ENGINEERING PART C-METHODS

The inhibitory and combinative mechanism of HZ08 with P-glycoprotein expressed on the membrane of Caco-2 cell line

(2013) Yanyan Zhang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Accelerated Caco-2 cell permeability model for drug discovery

(2013) E. Sevin et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Real-time analysis of P-glycoprotein-mediated drug transport across primary intestinal epithelium three-dimensionally cultured in vitro

(2012) Tomohiro Mizutani et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Establishment of a robust hepatitis C virus replicon cell line over-expressing P-glycoprotein that facilitates analysis of P-gp drug transporter effects on inhibitor antiviral activity

(2012) Dennis Hernandez et al.   BIOCHEMICAL PHARMACOLOGY

Reversal of P-glycoprotein-mediated multidrug resistance by a synthetic α-aminoxy peptidomimetic

(2012) Bin Ma et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

P-glycoprotein mediated efflux in Caco-2 cell monolayers: The influence of herbals on digoxin transport

(2012) Enoche F. Oga et al.   JOURNAL OF ETHNOPHARMACOLOGY

The P-glycoprotein multidrug transporter

(2011) Frances J. Sharom   Essays in Biochemistry

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

(2011) Toshiro Sato et al.   GASTROENTEROLOGY

20(S)-Ginsenoside Rh2 Noncompetitively Inhibits P-Glycoprotein In Vitro and In Vivo: A Case for Herb-Drug Interactions

(2010) J. Zhang et al.   DRUG METABOLISM AND DISPOSITION

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE

P-gp Inhibition Potential in Cell-Based Models: Which “Calculation” Method is the Most Accurate?

(2008) Praveen V. Balimane et al.   AAPS Journal

Structure, function and regulation of P-glycoprotein and its clinical relevance in drug disposition

(2008) S.-F. Zhou   XENOBIOTICA