Stereoselective Property of 20(S)-Protopanaxadiol Ocotillol Type Epimers Affects Its Absorption and Also the Inhibition of P-Glycoprotein

Effects of ginsenosides on the expression of cytochrome P450s and transporters involved in cholesterol metabolism

(2013) Atsushi Kawase et al.   Journal of Natural Medicines

Stereoselective determination of ginsenosides Rg3 and Rh2 epimers in rat plasma by LC-MS/MS: Application to a pharmacokinetic study

(2013) Soo Hyeon Bae et al.   JOURNAL OF SEPARATION SCIENCE

Stereoisomers ginsenosides-20(S)-Rg3 and -20(R)-Rg3 differentially induce angiogenesis through peroxisome proliferator-activated receptor-gamma

(2012) Hoi-Hin Kwok et al.   BIOCHEMICAL PHARMACOLOGY

Stereospecificity of ginsenoside Rg3 in promotion of the immune response to ovalbumin in mice

(2012) X. Wei et al.   INTERNATIONAL IMMUNOLOGY

Determination of 20(S)-protopanaxadiol ocotillol type epimers in rat plasma by liquid chromatography tandem mass spectrometry

(2012) Wenyan Wang et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Stereoselective Regulations of P-Glycoprotein by Ginsenoside Rh2 Epimers and the Potential Mechanisms From the View of Pharmacokinetics

(2012) Jingwei Zhang et al.   PLoS One

The two enantiomers of tetrahydropalmatine are inhibitors of P-gp, but not inhibitors of MRP1 or BCRP

(2012) Siyuan Sun et al.   XENOBIOTICA

Isolation and analysis of ginseng: advances and challenges

(2011) Lian-Wen Qi et al.   NATURAL PRODUCT REPORTS

Identification of 20(S)-Protopanaxadiol Metabolites in Human Liver Microsomes and Human Hepatocytes

(2010) L. Li et al.   DRUG METABOLISM AND DISPOSITION

20(S)-Ginsenoside Rh2 Noncompetitively Inhibits P-Glycoprotein In Vitro and In Vivo: A Case for Herb-Drug Interactions

(2010) J. Zhang et al.   DRUG METABOLISM AND DISPOSITION

Stereospecificity of hydroxyl group at C-20 in antiproliferative action of ginsenoside Rh2 on prostate cancer cells

(2010) Jie Liu et al.   FITOTERAPIA

Study on the structure–function relationship of 20(S)-panaxadiol and its epimeric derivatives in myocardial injury induced by isoproterenol

(2010) Tian Wang et al.   FITOTERAPIA

Intestinal absorption mechanisms of ginsenoside Rh2: stereoselectivity and involvement of ABC transporters

(2010) Y. Gu et al.   XENOBIOTICA

20(R)-Ginsenoside Rh2, not 20(S), is a selective osteoclastgenesis inhibitor without any cytotoxicity

(2009) Jie Liu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Ginseng Compounds: An Update on their Molecular Mechanisms and Medical Applications

(2009) Jian-Ming Lu et al.   Current Vascular Pharmacology

Interactions Between Herbal Medicines and Prescribed Drugs

(2009) Angelo A. Izzo et al.   DRUGS

Selective inhibition of MDR1 (ABCB1) by HM30181 increases oral bioavailability and therapeutic efficacy of paclitaxel

(2009) Jin-Oh Kwak et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

20S-Protopanaxadiol Inhibits P-Glycoprotein in Multidrug Resistant Cancer Cells

(2009) Yan Zhao et al.   PLANTA MEDICA

A phase I trial of continuous infusion of the multidrug resistance inhibitor zosuquidar with daunorubicin and cytarabine in acute myeloid leukemia

(2008) Jeffrey E. Lancet et al.   LEUKEMIA RESEARCH

Determination and modelling of stereoselective interactions of ligands with drug transporters: A key dimension in the understanding of drug disposition

(2008) P. Bhatia et al.   XENOBIOTICA