Bile acid-induced “Minority MOMP” promotes esophageal carcinogenesis while maintaining apoptotic resistance via Mcl-1

Cancer statistics, 2018

(2018) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

MetaboAnalyst 4.0: towards more transparent and integrative metabolomics analysis

(2018) Jasmine Chong et al.   NUCLEIC ACIDS RESEARCH

Iterative optimization yields Mcl-1–targeting stapled peptides with selective cytotoxicity to Mcl-1–dependent cancer cells

(2018) Raheleh Rezaei Araghi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

iBH3: simple, fixable BH3 profiling to determine apoptotic priming in primary tissue by flow cytometry

(2016) Jeremy Ryan et al.   BIOLOGICAL CHEMISTRY

Key Survival Factor, Mcl-1, Correlates with Sensitivity to Combined Bcl-2/Bcl-xL Blockade

(2016) Michelle M. Williams et al.   MOLECULAR CANCER RESEARCH

The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models

(2016) András Kotschy et al.   NATURE

Epidemiology of Barrett’s Esophagus and Esophageal Adenocarcinoma

(2015) Thomas M. Runge et al.   GASTROENTEROLOGY CLINICS OF NORTH AMERICA

Limited Mitochondrial Permeabilization Causes DNA Damage and Genomic Instability in the Absence of Cell Death

(2015) Gabriel Ichim et al.   MOLECULAR CELL

Caspase-3 Promotes Genetic Instability and Carcinogenesis

(2015) Xinjian Liu et al.   MOLECULAR CELL

Oxidative phosphorylation-dependent regulation of cancer cell apoptosis in response to anticancer agents

(2015) N Yadav et al.   Cell Death & Disease

Exploring the Recent Trend in Esophageal Adenocarcinoma Incidence and Mortality Using Comparative Simulation Modeling

(2014) C. Y. Kong et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

OpenComet: An automated tool for comet assay image analysis

(2014) Benjamin M. Gyori et al.   Redox Biology

Depletion of end-binding protein 1 (EB1) promotes apoptosis of human non-small-cell lung cancer cells via reactive oxygen species and Bax-mediated mitochondrial dysfunction

(2013) Min-Jung Kim et al.   CANCER LETTERS

Programming cancer cells for high expression levels of Mcl1

(2013) Franziska Ertel et al.   EMBO REPORTS

Apoptosis Regulation at the Mitochondrial Outer Membrane

(2013) Laura A. Gillies et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Mitochondrial Regulation of Cell Death

(2013) S. W. G. Tait et al.   Cold Spring Harbor Perspectives in Biology

Trends in esophageal adenocarcinoma incidence and mortality

(2012) Chin Hur et al.   CANCER

Cell survival, DNA damage, and oncogenic transformation after a transient and reversible apoptotic response

(2012) Ho Lam Tang et al.   MOLECULAR BIOLOGY OF THE CELL

Delving deeper: MCL-1's contributions to normal and cancer biology

(2012) Rhonda M. Perciavalle et al.   TRENDS IN CELL BIOLOGY

Prolonged exposure to acid and bile induces chromosome abnormalities that precede malignant transformation of benign Barrett’s epithelium

(2012) Manisha Bajpai et al.   Molecular Cytogenetics

Deoxycholic acid causes DNA damage while inducing apoptotic resistance through NF-κB activation in benign Barrett's epithelial cells

(2011) Xiaofang Huo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Measuring and Modeling Apoptosis in Single Cells

(2011) Sabrina L. Spencer et al.   CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Molecular biology of Bax and Bak activation and action

(2010) Dana Westphal et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The landscape of somatic copy-number alteration across human cancers

(2010) Rameen Beroukhim et al.   NATURE

Mitochondria and cell death: outer membrane permeabilization and beyond

(2010) Stephen W. G. Tait et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

TRAIL treatment provokes mutations in surviving cells

(2010) M M Lovric et al.   ONCOGENE

Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity

(2010) F. Weinberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unlike Esophageal Squamous Cells, Barrett's Epithelial Cells Resist Apoptosis by Activating the Nuclear Factor- B Pathway

(2009) K. Hormi-Carver et al.   CANCER RESEARCH

Reactive Oxygen Species-Dependent Activation of Bax and Poly(ADP-ribose) Polymerase-1 Is Required for Mitochondrial Cell Death Induced by Triterpenoid Pristimerin in Human Cervical Cancer Cells

(2009) J.-Y. Byun et al.   MOLECULAR PHARMACOLOGY

Bile Acid Exposure Up-regulates Tuberous Sclerosis Complex 1/Mammalian Target of Rapamycin Pathway in Barrett's-Associated Esophageal Adenocarcinoma

(2008) C.-J. Yen et al.   CANCER RESEARCH