Oxidative phosphorylation-dependent regulation of cancer cell apoptosis in response to anticancer agents

Human OXR1 maintains mitochondrial DNA integrity and counteracts hydrogen peroxide-induced oxidative stress by regulating antioxidant pathways involving p21

(2014) Mingyi Yang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Discrete mechanisms of mTOR and cell cycle regulation by AMPK agonists independent of AMPK

(2014) X. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transformations of the macromolecular landscape at mitochondria during DNA-damage-induced apoptotic cell death

(2014) N Yadav et al.   Cell Death & Disease

ABT-199: Taking Dead Aim at BCL-2

(2013) Matthew S. Davids et al.   CANCER CELL

Mitochondrial Cardiolipin Is Required for Nlrp3 Inflammasome Activation

(2013) Shankar S. Iyer et al.   IMMUNITY

Mitochondrial and postmitochondrial survival signaling in cancer

(2013) Neelu Yadav et al.   MITOCHONDRION

ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets

(2013) Andrew J Souers et al.   NATURE MEDICINE

Mitochondria: gatekeepers of response to chemotherapy

(2013) Kristopher A. Sarosiek et al.   TRENDS IN CELL BIOLOGY

Regulation of the Intrinsic Apoptosis Pathway by Reactive Oxygen Species

(2012) Chu-Chiao Wu et al.   ANTIOXIDANTS & REDOX SIGNALING

Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis

(2012) Kenichi Shimada et al.   IMMUNITY

Resveratrol depletes mitochondrial DNA and inhibition of autophagy enhances resveratrol-induced caspase activation

(2012) Varun Prabhu et al.   MITOCHONDRION

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

(2012) Cole Trapnell et al.   Nature Protocols

BAX supports the mitochondrial network, promoting bioenergetics in nonapoptotic cells

(2011) Rebecca J. Boohaker et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Mitochondria as Therapeutic Targets for the Treatment of Malignant Disease

(2011) Simone Fulda et al.   ANTIOXIDANTS & REDOX SIGNALING

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Mitochondrial Dysfunction Impairs Tumor Suppressor p53 Expression/Function

(2011) Shannon Compton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)

(2011) Ariel C. Bulua et al.   JOURNAL OF EXPERIMENTAL MEDICINE

ROS-mediated mechanisms of autophagy stimulation and their relevance in cancer therapy

(2010) Michael Dewaele et al.   Autophagy

Genetic insights into OXPHOS defect and its role in cancer

(2010) Dhyan Chandra et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Induction of regulatory T cells by macrophages is dependent on production of reactive oxygen species

(2010) Marina D. Kraaij et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Loss of p53 causes mitochondrial DNA depletion and altered mitochondrial reactive oxygen species homeostasis

(2009) Maria A. Lebedeva et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Decreased mitochondrial DNA content in blood samples of patients with stage I breast cancer

(2009) Peng Xia et al.   BMC CANCER

4E-BP Extends Lifespan upon Dietary Restriction by Enhancing Mitochondrial Activity in Drosophila

(2009) Brian M. Zid et al.   CELL

Bcl-2 Inhibitors: Targeting Mitochondrial Apoptotic Pathways in Cancer Therapy

(2009) M. H. Kang et al.   CLINICAL CANCER RESEARCH

TZDs reduce mitochondrial ROS production and enhance mitochondrial biogenesis

(2008) Kazuo Fujisawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Selective anticancer strategies via intervention of the death pathways relevant to cell transformation

(2008) Q-X Li et al.   CELL DEATH AND DIFFERENTIATION

Etoposide Induces ATM-Dependent Mitochondrial Biogenesis through AMPK Activation

(2008) Xuan Fu et al.   PLoS One

Investigations of the potential effects of phosphorylation of the MWFE and ESSS subunits on complex I activity and assembly

(2007) N. Yadava et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY