Norovirus encounters in the gut: multifaceted interactions and disease outcomes

Calicivirus VP2 forms a portal-like assembly following receptor engagement

(2019) Michaela J. Conley et al.   NATURE

Autophagy and Noroviruses

(2019) Kevin Furlong et al.   Viruses-Basel

A Secreted Viral Nonstructural Protein Determines Intestinal Norovirus Pathogenesis

(2019) Sanghyun Lee et al.   Cell Host & Microbe

Sera Antibody Repertoire Analyses Reveal Mechanisms of Broad and Pandemic Strain Neutralizing Responses after Human Norovirus Vaccination

(2019) Lisa C. Lindesmith et al.   IMMUNITY

Bile salts alter the mouse norovirus capsid conformation; possible implications for cell attachment and immune evasion.

(2019) Michael B. Sherman et al.   JOURNAL OF VIROLOGY

Composition of the Intestinal Microbiota Determines the Outcome of Virus-Triggered Colitis in Mice

(2019) Silvia Bolsega et al.   Frontiers in Immunology

Interactions between noroviruses, the host, and the microbiota

(2019) Forrest C Walker et al.   Current Opinion in Virology

Interferon lambda (IFN-λ) efficiently blocks norovirus transmission in a mouse model

(2018) Joana Rocha-Pereira et al.   ANTIVIRAL RESEARCH

A Metabolite-Triggered Tuft Cell-ILC2 Circuit Drives Small Intestinal Remodeling

(2018) Christoph Schneider et al.   CELL

Detection of Succinate by Intestinal Tuft Cells Triggers a Type 2 Innate Immune Circuit

(2018) Marija S. Nadjsombati et al.   IMMUNITY

The dual tropism of noroviruses

(2018) Christiane E. Wobus   JOURNAL OF VIROLOGY

Atomic Structure of the Murine Norovirus Protruding Domain and Soluble CD300lf Receptor Complex

(2018) Turgay Kilic et al.   JOURNAL OF VIROLOGY

Activation of intestinal tuft cell-expressed Sucnr1 triggers type 2 immunity in the mouse small intestine

(2018) Weiwei Lei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tropism for tuft cells determines immune promotion of norovirus pathogenesis

(2018) Craig B. Wilen et al.   SCIENCE

Paneth Cells during Viral Infection and Pathogenesis

(2018) Mayumi Holly et al.   Viruses-Basel

HOIL1 is essential for the induction of type I and III interferons by MDA5 and regulates persistent murine norovirus infection

(2018) Donna A. MacDuff et al.   JOURNAL OF VIROLOGY

Natural Secretory Immunoglobulins Promote Enteric Viral Infections

(2018) Holly Turula et al.   JOURNAL OF VIROLOGY

Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor

(2018) Christopher A. Nelson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Monoclonal Antibodies That Neutralize Pandemic GII.4 Noroviruses

(2018) Gabriela Alvarado et al.   GASTROENTEROLOGY

Structural Basis for Human Norovirus Capsid Binding to Bile Acids

(2018) Turgay Kilic et al.   JOURNAL OF VIROLOGY

Differentiation and Protective Capacity of Virus-Specific CD8 + T Cells Suggest Murine Norovirus Persistence in an Immune-Privileged Enteric Niche

(2017) Vesselin T. Tomov et al.   IMMUNITY

Autophagy protein ATG16L1 prevents necroptosis in the intestinal epithelium

(2017) Yu Matsuzawa-Ishimoto et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Expression of Ifnlr1 on Intestinal Epithelial Cells Is Critical to the Antiviral Effects of Interferon Lambda against Norovirus and Reovirus

(2017) Megan T. Baldridge et al.   JOURNAL OF VIROLOGY

Protect this house: cytosolic sensing of viruses

(2017) Michael J McFadden et al.   Current Opinion in Virology

Static and Evolving Norovirus Genotypes: Implications for Epidemiology and Immunity

(2017) Gabriel I. Parra et al.   PLoS Pathogens

Interferon-Lambda: A Potent Regulator of Intestinal Viral Infections

(2017) Sanghyun Lee et al.   Frontiers in Immunology

The major targets of acute norovirus infection are immune cells in the gut-associated lymphoid tissue

(2017) Katrina R. Grau et al.   Nature Microbiology

Norovirus in symptomatic and asymptomatic individuals: cytokines and viral shedding

(2016) K. L. Newman et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

The Gut Bacteria-Driven Obesity Development

(2016) Debora Compare et al.   DIGESTIVE DISEASES

Detection of human norovirus in intestinal biopsies from immunocompromised transplant patients

(2016) Umesh C. Karandikar et al.   JOURNAL OF GENERAL VIROLOGY

Functional receptor molecules CD300lf and CD300ld within the CD300 family enable murine noroviruses to infect cells

(2016) Kei Haga et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Discovery of a proteinaceous cellular receptor for a norovirus

(2016) R. C. Orchard et al.   SCIENCE

Replication of human noroviruses in stem cell-derived human enteroids

(2016) K. Ettayebi et al.   SCIENCE

Type I Interferon Receptor Deficiency in Dendritic Cells Facilitates Systemic Murine Norovirus Persistence Despite Enhanced Adaptive Immunity

(2016) Timothy J. Nice et al.   PLoS Pathogens

Genotype Considerations for Virus-Like Particle-Based Bivalent Norovirus Vaccine Composition

(2015) Maria Malm et al.   Clinical and Vaccine Immunology

Serological Correlates of Protection against a GII.4 Norovirus

(2015) Robert L. Atmar et al.   Clinical and Vaccine Immunology

Norovirus immunology: Of mice and mechanisms

(2015) Kira L. Newman et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A Multihit Model

(2015) Lydia M. Keubler et al.   INFLAMMATORY BOWEL DISEASES

Human norovirus culture in B cells

(2015) Melissa K Jones et al.   Nature Protocols

A Working Model of How Noroviruses Infect the Intestine

(2015) Stephanie M. Karst et al.   PLoS Pathogens

Role of the Microbiota in Immunity and Inflammation

(2014) Yasmine Belkaid et al.   CELL

Advances in Norovirus Biology

(2014) Stephanie M. Karst et al.   Cell Host & Microbe

The State of Norovirus Vaccines

(2014) K. Debbink et al.   CLINICAL INFECTIOUS DISEASES

Norovirus infection in immunocompromised hosts

(2014) K.Y. Green   CLINICAL MICROBIOLOGY AND INFECTION

Shedding of norovirus in symptomatic and asymptomatic infections

(2014) P. F. M. TEUNIS et al.   EPIDEMIOLOGY AND INFECTION

Norovirus Triggered Microbiota-driven Mucosal Inflammation in Interleukin 10-deficient Mice

(2014) Marijana Basic et al.   INFLAMMATORY BOWEL DISEASES

Advances in Laboratory Methods for Detection and Typing of Norovirus

(2014) Jan Vinjé   JOURNAL OF CLINICAL MICROBIOLOGY

Pattern of Circulation of Norovirus GII Strains during Natural Infection

(2014) J. A. Ayukekbong et al.   JOURNAL OF CLINICAL MICROBIOLOGY

High Serum Levels of Norovirus Genotype-Specific Blocking Antibodies Correlate With Protection From Infection in Children

(2014) M. Malm et al.   JOURNAL OF INFECTIOUS DISEASES

Efficient Norovirus and Reovirus Replication in the Mouse Intestine Requires Microfold (M) Cells

(2014) M. B. Gonzalez-Hernandez et al.   JOURNAL OF VIROLOGY

Global prevalence of norovirus in cases of gastroenteritis: a systematic review and meta-analysis

(2014) Sharia M Ahmed et al.   LANCET INFECTIOUS DISEASES

An enteric virus can replace the beneficial function of commensal bacteria

(2014) Elisabeth Kernbauer et al.   NATURE

Commensal microbes and interferon-  determine persistence of enteric murine norovirus infection

(2014) M. T. Baldridge et al.   SCIENCE

Virus-helminth coinfection reveals a microbiota-independent mechanism of immunomodulation

(2014) L. C. Osborne et al.   SCIENCE

Interferon-  cures persistent murine norovirus infection in the absence of adaptive immunity

(2014) T. J. Nice et al.   SCIENCE

Enteric bacteria promote human and mouse norovirus infection of B cells

(2014) M. K. Jones et al.   SCIENCE

The Effect of Malnutrition on Norovirus Infection

(2014) D. Hickman et al.   mBio

Proposal for a unified norovirus nomenclature and genotyping

(2013) Annelies Kroneman et al.   ARCHIVES OF VIROLOGY

The CD300 molecules: an emerging family of regulators of the immune system

(2013) F. Borrego   BLOOD

Gut Microbiota Regulates Bile Acid Metabolism by Reducing the Levels of Tauro-beta-muricholic Acid, a Naturally Occurring FXR Antagonist

(2013) Sama I. Sayin et al.   Cell Metabolism

Dysbiosis contributes to fibrogenesis in the course of chronic liver injury in mice

(2013) Samuele De Minicis et al.   HEPATOLOGY

Cytosolic Sensing of Viruses

(2013) Delphine Goubau et al.   IMMUNITY

Genotypic and Epidemiologic Trends of Norovirus Outbreaks in the United States, 2009 to 2013

(2013) E. Vega et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Multiple effects of dendritic cell depletion on murine norovirus infection

(2013) M. D. Elftman et al.   JOURNAL OF GENERAL VIROLOGY

Emergence of New Pandemic GII.4 Sydney Norovirus Strain Correlates With Escape From Herd Immunity

(2013) Kari Debbink et al.   JOURNAL OF INFECTIOUS DISEASES

Histo-Blood Group Antigen-Like Substances of Human Enteric Bacteria as Specific Adsorbents for Human Noroviruses

(2013) T. Miura et al.   JOURNAL OF VIROLOGY

Persistent Enteric Murine Norovirus Infection Is Associated with Functionally Suboptimal Virus-Specific CD8 T Cell Responses

(2013) V. T. Tomov et al.   JOURNAL OF VIROLOGY

Norwalk Virus Minor Capsid Protein VP2 Associates within the VP1 Shell Domain

(2013) S. Vongpunsawad et al.   JOURNAL OF VIROLOGY

Global Causes of Diarrheal Disease Mortality in Children

(2013) Claudio F. Lanata et al.   PLoS One

Murine norovirus protein NS1/2 aspartate to glutamate mutation, sufficient for persistence, reorients side chain of surface exposed tryptophan within a novel structured domain

(2013) Brendan N. Borin et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Identification of Immune and Viral Correlates of Norovirus Protective Immunity through Comparative Study of Intra-Cluster Norovirus Strains

(2013) Shu Zhu et al.   PLoS Pathogens

Murine norovirus infection does not cause major disruptions in the murine intestinal microbiota

(2013) Adam M Nelson et al.   Microbiome

Incidence of Post-Infectious Irritable Bowel Syndrome and Functional Intestinal Disorders Following a Water-Borne Viral Gastroenteritis Outbreak

(2012) Barbara Zanini et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Nondegradative Role of Atg5-Atg12/ Atg16L1 Autophagy Protein Complex in Antiviral Activity of Interferon Gamma

(2012) Seungmin Hwang et al.   Cell Host & Microbe

Hospitalizations and Mortality Associated With Norovirus Outbreaks in Nursing Homes, 2009-2010

(2012) Tarak K. Trivedi et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Essential Cell-Autonomous Role for Interferon (IFN) Regulatory Factor 1 in IFN- -Mediated Inhibition of Norovirus Replication in Macrophages

(2012) N. S. Maloney et al.   JOURNAL OF VIROLOGY

A Single-Amino-Acid Change in Murine Norovirus NS1/2 Is Sufficient for Colonic Tropism and Persistence

(2012) T. J. Nice et al.   JOURNAL OF VIROLOGY

Critical Role for Interferon Regulatory Factor 3 (IRF-3) and IRF-7 in Type I Interferon-Mediated Control of Murine Norovirus Replication

(2012) L. B. Thackray et al.   JOURNAL OF VIROLOGY

Disruption of the Human Gut Microbiota following Norovirus Infection

(2012) Adam M. Nelson et al.   PLoS One

Norovirus gastroenteritis causes severe and lethal complications after chemotherapy and hematopoietic stem cell transplantation

(2011) S. Schwartz et al.   BLOOD

Farnesoid X receptor activation inhibits inflammation and preserves the intestinal barrier in inflammatory bowel disease

(2011) R. M. Gadaleta et al.   GUT

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

(2011) Taro Kawai et al.   IMMUNITY

Norovirus Vaccine against Experimental Human Norwalk Virus Illness

(2011) Robert L. Atmar et al.   NEW ENGLAND JOURNAL OF MEDICINE

Norovirus and severe chronic gastroenteritis in pediatric stem cell transplantation: The plot thickens

(2011) Naim Alkhouri et al.   PEDIATRIC TRANSPLANTATION

Chronic norovirus infection in pediatric hematopoietic stem cell transplant recipients: A cause of prolonged intestinal failure requiring intensive nutritional support

(2011) M. A. Saif et al.   PEDIATRIC TRANSPLANTATION

The Bile Acid Receptor GPBAR-1 (TGR5) Modulates Integrity of Intestinal Barrier and Immune Response to Experimental Colitis

(2011) Sabrina Cipriani et al.   PLoS One

Norovirus Regulation of the Innate Immune Response and Apoptosis Occurs via the Product of the Alternative Open Reading Frame 4

(2011) Nora McFadden et al.   PLoS Pathogens

Importance and regulation of the colonic mucus barrier in a mouse model of colitis

(2010) J. Petersson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Adaptive Immune Regulation in the Gut: T Cell–Dependent and T Cell–Independent IgA Synthesis

(2010) Sidonia Fagarasan et al.   Annual Review of Immunology

Virus-Plus-Susceptibility Gene Interaction Determines Crohn's Disease Gene Atg16L1 Phenotypes in Intestine

(2010) Ken Cadwell et al.   CELL

Clinical characteristics of viral intestinal infection in preterm and term neonates

(2010) S. Bagci et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Viral shape-shifting: norovirus evasion of the human immune system

(2010) Eric F. Donaldson et al.   NATURE REVIEWS MICROBIOLOGY

Phylodynamic Reconstruction Reveals Norovirus GII.4 Epidemic Expansions and their Molecular Determinants

(2010) J. Joukje Siebenga et al.   PLoS Pathogens

Rapid Evolution of Pandemic Noroviruses of the GII.4 Lineage

(2010) Rowena A. Bull et al.   PLoS Pathogens

Muc2 Protects against Lethal Infectious Colitis by Disassociating Pathogenic and Commensal Bacteria from the Colonic Mucosa

(2010) Kirk S. B. Bergstrom et al.   PLoS Pathogens

Bayesian coalescent inference reveals high evolutionary rates and expansion of Norovirus populations

(2009) Matías Victoria et al.   INFECTION GENETICS AND EVOLUTION

Genetic Diversity among Food-Borne and Waterborne Norovirus Strains Causing Outbreaks in Sweden

(2009) M. Lysen et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Norovirus in a Dutch tertiary care hospital (2002–2007): frequent nosocomial transmission and dominance of GIIb strains in young children

(2009) M.F.C. Beersma et al.   JOURNAL OF HOSPITAL INFECTION

Norovirus Illness Is a Global Problem: Emergence and Spread of Norovirus GII.4 Variants, 2001–2007

(2009) J. Joukje Siebenga et al.   JOURNAL OF INFECTIOUS DISEASES

Ganglioside-Linked Terminal Sialic Acid Moieties on Murine Macrophages Function as Attachment Receptors for Murine Noroviruses

(2009) S. Taube et al.   JOURNAL OF VIROLOGY

Type I and Type II Interferons Inhibit the Translation of Murine Norovirus Proteins

(2009) H. Changotra et al.   JOURNAL OF VIROLOGY

Norovirus Gastroenteritis

(2009) Roger I. Glass et al.   NEW ENGLAND JOURNAL OF MEDICINE

High Prevalence of Prolonged Norovirus Shedding and Illness among Hospitalized Patients: A Model for In Vivo Molecular Evolution

(2008) J. Joukje Siebenga et al.   JOURNAL OF INFECTIOUS DISEASES

Norwalk virus: How infectious is it?

(2008) Peter F.M. Teunis et al.   JOURNAL OF MEDICAL VIROLOGY

A Single Amino Acid Substitution in the Murine Norovirus Capsid Protein Is Sufficient for Attenuation In Vivo

(2008) D. Bailey et al.   JOURNAL OF VIROLOGY

Antibody Is Critical for the Clearance of Murine Norovirus Infection

(2008) K. A. Chachu et al.   JOURNAL OF VIROLOGY

Structural Basis for the Receptor Binding Specificity of Norwalk Virus

(2008) W. Bu et al.   JOURNAL OF VIROLOGY

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

(2008) Ken Cadwell et al.   NATURE

Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface

(2008) S. Vaishnava et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria

(2008) M. E. V. Johansson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immune Mechanisms Responsible for Vaccination against and Clearance of Mucosal and Lymphatic Norovirus Infection

(2008) Karen A. Chachu et al.   PLoS Pathogens

MDA-5 Recognition of a Murine Norovirus

(2008) Stephen A. McCartney et al.   PLoS Pathogens