Metabolic and regulatory insights from the experimental horizontal gene transfer of the aurofusarin and bikaverin gene clusters to Aspergillus nidulans

Linking secondary metabolites to gene clusters through genome sequencing of six diverseAspergillusspecies

(2018) Inge Kjærbølling et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conserved Responses in a War of Small Molecules between a Plant-Pathogenic Bacterium and Fungi

(2018) Joseph E. Spraker et al.   mBio

HEx: A heterologous expression platform for the discovery of fungal natural products

(2018) Colin J. B. Harvey et al.   Science Advances

The birth, evolution and death of metabolic gene clusters in fungi

(2018) Antonis Rokas et al.   NATURE REVIEWS MICROBIOLOGY

Investigation of inter- and intraspecies variation through genome sequencing of Aspergillus section Nigri

(2018) Tammi C. Vesth et al.   NATURE GENETICS

Fungal secondary metabolism: regulation, function and drug discovery

(2018) Nancy P. Keller   NATURE REVIEWS MICROBIOLOGY

Enhancing the Production of the Fungal Pigment Aurofusarin in Fusarium graminearum

(2018) Klaus Westphal et al.   Toxins

A scalable platform to identify fungal secondary metabolites and their gene clusters

(2017) Kenneth D Clevenger et al.   Nature Chemical Biology

Functional horizontal gene transfer from bacteria to eukaryotes

(2017) Filip Husnik et al.   NATURE REVIEWS MICROBIOLOGY

antiSMASH 4.0—improvements in chemistry prediction and gene cluster boundary identification

(2017) Kai Blin et al.   NUCLEIC ACIDS RESEARCH

Extensive horizontal gene transfer in cheese-associated bacteria

(2017) Kevin S Bonham et al.   eLife

Global analysis of biosynthetic gene clusters reveals vast potential of secondary metabolite production in Penicillium species

(2017) Jens Christian Nielsen et al.   Nature Microbiology

Insights into natural products biosynthesis from analysis of 490 polyketide synthases from Fusarium

(2016) Daren W. Brown et al.   FUNGAL GENETICS AND BIOLOGY

Ralstonia solanacearum lipopeptide induces chlamydospore development in fungi and facilitates bacterial entry into fungal tissues

(2016) Joseph E Spraker et al.   ISME Journal

Transcriptional regulation of a horizontally transferred gene from bacterium to chordate

(2016) Yasunori Sasakura et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The completed genome sequence of the pathogenic ascomycete fungus Fusarium graminearum

(2015) Robert King et al.   BMC GENOMICS

Genetic engineering, high resolution mass spectrometry and nuclear magnetic resonance spectroscopy elucidate the bikaverin biosynthetic pathway in Fusarium fujikuroi

(2015) Birgit Arndt et al.   FUNGAL GENETICS AND BIOLOGY

Refining the pH response inAspergillus nidulans: a modulatory triad involving PacX, a novel zinc binuclear cluster protein

(2015) Henk-Jan Bussink et al.   MOLECULAR MICROBIOLOGY

Examining the Evolution of the Regulatory Circuit Controlling Secondary Metabolism and Development in the Fungal Genus Aspergillus

(2015) Abigail L. Lind et al.   PLoS Genetics

The importance of mass spectrometric dereplication in fungal secondary metabolite analysis

(2015) Kristian F. Nielsen et al.   Frontiers in Microbiology

Fungal metabolic gene clusters—caravans traveling across genomes and environments

(2015) Jennifer H. Wisecaver et al.   Frontiers in Microbiology

Aggressive dereplication using UHPLC–DAD–QTOF: screening extracts for up to 3000 fungal secondary metabolites

(2014) Andreas Klitgaard et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Horizontal Gene Transfer in Eukaryotic Plant Pathogens

(2014) Darren Soanes et al.   Annual Review of Phytopathology

Minimal, encapsulated proteomic-sample processing applied to copy-number estimation in eukaryotic cells

(2014) Nils A Kulak et al.   NATURE METHODS

The Fusarium graminearum Genome Reveals More Secondary Metabolite Gene Clusters and Hints of Horizontal Gene Transfer

(2014) Christian M. K. Sieber et al.   PLoS One

The Evolution of Fungal Metabolic Pathways

(2014) Jennifer H. Wisecaver et al.   PLoS Genetics

Birth, death and horizontal transfer of the fumonisin biosynthetic gene cluster during the evolutionary diversification ofFusarium

(2013) Robert H. Proctor et al.   MOLECULAR MICROBIOLOGY

Repeated loss of an anciently horizontally transferred gene cluster in Botrytis

(2013) Matthew A. Campbell et al.   MYCOLOGIA

A Functional Bikaverin Biosynthesis Gene Cluster in Rare Strains of Botrytis cinerea Is Positively Controlled by VELVET

(2013) Julia Schumacher et al.   PLoS One

Adaptation to pH and Role of PacC in the Rice Blast Fungus Magnaporthe oryzae

(2013) Patricia Landraud et al.   PLoS One

Deciphering the Cryptic Genome: Genome-wide Analyses of the Rice Pathogen Fusarium fujikuroi Reveal Complex Regulation of Secondary Metabolism and Novel Metabolites

(2013) Philipp Wiemann et al.   PLoS Pathogens

Biosynthesis of Fusarubins Accounts for Pigmentation of Fusarium fujikuroi Perithecia

(2012) Lena Studt et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

LC-MS/MS method for the determination of the fungal pigment bikaverin in maize kernels as an indicator of ear rot

(2012) M. Busman et al.   Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment

Redirection of pigment biosynthesis to isocoumarins in Fusarium

(2012) Jens Laurids Sørensen et al.   FUNGAL GENETICS AND BIOLOGY

Horizontal Transfer and Death of a Fungal Secondary Metabolic Gene Cluster

(2012) Matthew A. Campbell et al.   Genome Biology and Evolution

Accurate prediction of secondary metabolite gene clusters in filamentous fungi

(2012) M. R. Andersen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Versatile Enzyme Expression and Characterization System for Aspergillus nidulans, with the Penicillium brevicompactum Polyketide Synthase Gene from the Mycophenolic Acid Gene Cluster as a Test Case

(2011) Bjarne G. Hansen et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Two Novel Classes of Enzymes Are Required for the Biosynthesis of Aurofusarin inFusarium graminearum

(2011) Rasmus J. N. Frandsen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dereplication of Microbial Natural Products by LC-DAD-TOFMS

(2011) Kristian F. Nielsen et al.   JOURNAL OF NATURAL PRODUCTS

Gene transfer into the fungi

(2011) Thomas A. Richards et al.   Fungal Biology Reviews

Horizontal Transfer of a Large and Highly Toxic Secondary Metabolic Gene Cluster between Fungi

(2010) Jason C. Slot et al.   CURRENT BIOLOGY

SMURF: Genomic mapping of fungal secondary metabolite clusters

(2010) Nora Khaldi et al.   FUNGAL GENETICS AND BIOLOGY

Fungal secondary metabolites – Strategies to activate silent gene clusters

(2010) Axel A. Brakhage et al.   FUNGAL GENETICS AND BIOLOGY

FfVel1 and FfLae1, components of a velvet-like complex in Fusarium fujikuroi, affect differentiation, secondary metabolism and virulence

(2010) Philipp Wiemann et al.   MOLECULAR MICROBIOLOGY

Comparative genomics reveals mobile pathogenicity chromosomes in Fusarium

(2010) Li-Jun Ma et al.   NATURE

Functional and ecological impacts of horizontal gene transfer in eukaryotes

(2009) Patrick J Keeling   CURRENT OPINION IN GENETICS & DEVELOPMENT

Biosynthesis of the red pigment bikaverin inFusarium fujikuroi: genes, their function and regulation

(2009) Philipp Wiemann et al.   MOLECULAR MICROBIOLOGY

Neutrality of Foreign Complex Subunits in an Experimental Model of Lateral Gene Transfer

(2008) A. Wellner et al.   MOLECULAR BIOLOGY AND EVOLUTION

VelB/VeA/LaeA Complex Coordinates Light Signal with Fungal Development and Secondary Metabolism

(2008) O. Bayram et al.   SCIENCE

Evidence for horizontal transfer of a secondary metabolite gene cluster between fungi

(2008) Nora Khaldi et al.   GENOME BIOLOGY

Transient disruption of non-homologous end-joining facilitates targeted genome manipulations in the filamentous fungus Aspergillus nidulans

(2007) Jakob B. Nielsen et al.   FUNGAL GENETICS AND BIOLOGY

Integration of Horizontally Transferred Genes into Regulatory Interaction Networks Takes Many Million Years

(2007) M. J. Lercher et al.   MOLECULAR BIOLOGY AND EVOLUTION