Oxidative phosphorylation inhibition induces anticancerous changes in therapy‐resistant–acute myeloid leukemia patient cells

Atovaquone enhances doxorubicin’s efficacy via inhibiting mitochondrial respiration and STAT3 in aggressive thyroid cancer

(2018) Zhuo Lv et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Bioinformatics-based identification of miR-542-5p as a predictive biomarker in breast cancer therapy

(2018) Qiong-Ni Zhu et al.   HEREDITAS

Chemotherapy-Resistant Human Acute Myeloid Leukemia Cells Are Not Enriched for Leukemic Stem Cells but Require Oxidative Metabolism

(2017) Thomas Farge et al.   Cancer Discovery

Quantitative proteomic analysis of anticancer drug RH1 resistance in liver carcinoma

(2016) Marija Ger et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Microtubule destabilising agents: far more than just antimitotic anticancer drugs

(2016) Darcy Bates et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Combinational strategies of metformin and chemotherapy in cancers

(2016) Hui-Hui Zhang et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

The Role of PGC1  in Cancer Metabolism and its Therapeutic Implications

(2016) Z. Tan et al.   MOLECULAR CANCER THERAPEUTICS

The anti-malarial atovaquone increases radiosensitivity by alleviating tumour hypoxia

(2016) Thomas M. Ashton et al.   Nature Communications

Repurposing atovaquone: Targeting mitochondrial complex III and OXPHOS to eradicate cancer stem cells

(2016) Marco Fiorillo et al.   Oncotarget

Direct and indirect targeting of MYC to treat acute myeloid leukemia

(2015) Sam Brondfield et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Cathepsin D inhibitors as potential therapeutics for breast cancer treatment: Molecular docking and bioevaluation against triple-negative and triple-positive breast cancers

(2015) Hasitha Shilpa Anantaraju et al.   MOLECULAR DIVERSITY

Targeting mitochondria metabolism for cancer therapy

(2015) Samuel E Weinberg et al.   Nature Chemical Biology

Acute Myeloid Leukemia

(2015) Hartmut Döhner et al.   NEW ENGLAND JOURNAL OF MEDICINE

MYC and metabolism on the path to cancer

(2015) Annie L. Hsieh et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Calmodulin antagonists promote TRA-8 therapy of resistant pancreatic cancer

(2015) Kaiyu Yuan et al.   Oncotarget

Involvement of 14-3-3 Proteins in Regulating Tumor Progression of Hepatocellular Carcinoma

(2015) Yi-Ju Wu et al.   Cancers

Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis

(2014) William W Wheaton et al.   eLife

PGC1α Expression Defines a Subset of Human Melanoma Tumors with Increased Mitochondrial Capacity and Resistance to Oxidative Stress

(2013) Francisca Vazquez et al.   CANCER CELL

Drift time-specific collision energies enable deep-coverage data-independent acquisition proteomics

(2013) Ute Distler et al.   NATURE METHODS

Inhibition of Mitochondrial Translation as a Therapeutic Strategy for Human Acute Myeloid Leukemia

(2011) Marko Škrtić et al.   CANCER CELL

Metformin Decreases the Dose of Chemotherapy for Prolonging Tumor Remission in Mouse Xenografts Involving Multiple Cancer Cell Types

(2011) D. Iliopoulos et al.   CANCER RESEARCH

Development of cytarabine prodrugs and delivery systems for leukemia treatment

(2010) Bhupender S Chhikara et al.   Expert Opinion on Drug Delivery

Universal sample preparation method for proteome analysis

(2009) Jacek R Wiśniewski et al.   NATURE METHODS