Tumor-derived extracellular vesicles: insights into bystander effects of exosomes after irradiation

Low-level laser irradiation at a high power intensity increased human endothelial cell exosome secretion via Wnt signaling

(2018) Hesam Saghaei Bagheri et al.   LASERS IN MEDICAL SCIENCE

Exosomes Shuttle TREX1-Sensitive IFN-Stimulatory dsDNA from Irradiated Cancer Cells to DCs

(2018) Julie M. Diamond et al.   Cancer Immunology Research

Diabetic sera disrupted the normal exosome signaling pathway in human mesenchymal stem cells in vitro

(2018) Jafar Rezaie et al.   CELL AND TISSUE RESEARCH

Molecular lipid species in urinary exosomes as potential prostate cancer biomarkers

(2017) Tore Skotland et al.   EUROPEAN JOURNAL OF CANCER

Mass spectrometric detection of 27-hydroxycholesterol in breast cancer exosomes

(2017) Hanne Roberg-Larsen et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Exosomes from M1-Polarized Macrophages Potentiate the Cancer Vaccine by Creating a Pro-inflammatory Microenvironment in the Lymph Node

(2017) Lifang Cheng et al.   MOLECULAR THERAPY

Circulating exosomes carrying an immunosuppressive cargo interfere with cellular immunotherapy in acute myeloid leukemia

(2017) Chang-Sook Hong et al.   Scientific Reports

Radiation alters the cargo of exosomes released from squamous head and neck cancer cells to promote migration of recipient cells

(2017) Lisa Mutschelknaus et al.   Scientific Reports

CD63 Regulates Epstein-Barr Virus LMP1 Exosomal Packaging, Enhancement of Vesicle Production, and Noncanonical NF-κB Signaling

(2016) Stephanie N. Hurwitz et al.   JOURNAL OF VIROLOGY

Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes

(2016) Joanna Kowal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Secretomic analysis of extracellular vesicles originating from polyomavirus-negative and polyomavirus-positive Merkel cell carcinoma cell lines

(2016) Aelita Konstantinell et al.   PROTEOMICS

Myoferlin is a novel exosomal protein and functional regulator of cancer-derived exosomes

(2016) Arnaud Blomme et al.   Oncotarget

Exosomes Derived from Squamous Head and Neck Cancer Promote Cell Survival after Ionizing Radiation

(2016) Lisa Mutschelknaus et al.   PLoS One

Secreted primary human malignant mesothelioma exosome signature reflects oncogenic cargo

(2016) David W. Greening et al.   Scientific Reports

Bystander autophagy mediated by radiation-induced exosomal miR-7-5p in non-targeted human bronchial epithelial cells

(2016) Man Song et al.   Scientific Reports

Ionizing radiation affects protein composition of exosomes secreted in vitro from head and neck squamous cell carcinoma

(2015) Karol Jelonek et al.   ACTA BIOCHIMICA POLONICA

Matrix metalloproteinase 13-containing exosomes promote nasopharyngeal carcinoma metastasis

(2015) Yiwen You et al.   CANCER SCIENCE

The abscopal effect of local radiotherapy: using immunotherapy to make a rare event clinically relevant

(2015) Kobe Reynders et al.   CANCER TREATMENT REVIEWS

Protein kinase D1/2 is involved in the maturation of multivesicular bodies and secretion of exosomes in T and B lymphocytes

(2015) C Mazzeo et al.   CELL DEATH AND DIFFERENTIATION

Pathogenesis of pancreatic cancer exosome-induced lipolysis in adipose tissue

(2015) Gunisha Sagar et al.   GUT

The non-targeted effects of radiation are perpetuated by exosomes

(2015) Ammar Al-Mayah et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Exosome-mediated microRNA transfer plays a role in radiation-induced bystander effect

(2015) Shuai Xu et al.   RNA Biology

Exosomes released by keratinocytes modulate melanocyte pigmentation

(2015) Alessandra Lo Cicero et al.   Nature Communications

High expression of small GTPase Rab3D promotes cancer progression and metastasis

(2015) Jian Yang et al.   Oncotarget

Exosomes from bulk and stem cells from human prostate cancer have a differential microRNA content that contributes cooperatively over local and pre-metastatic niche

(2015) Catherine A. Sánchez et al.   Oncotarget

Cancer exosomes trigger mesenchymal stem cell differentiation into pro-angiogenic and pro-invasive myofibroblasts

(2015) Ridwana Chowdhury et al.   Oncotarget

Detection of Exosomal miRNAs in the Plasma of Melanoma Patients

(2015) Susan Pfeffer et al.   Journal of Clinical Medicine

Radiation increases the cellular uptake of exosomes through CD29/CD81 complex formation

(2014) Masaharu Hazawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cancer-Secreted miR-105 Destroys Vascular Endothelial Barriers to Promote Metastasis

(2014) Weiying Zhou et al.   CANCER CELL

Critical role of extracellular vesicles in modulating the cellular effects of cytokines

(2014) Géza Tamás Szabó et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Biogenesis and secretion of exosomes

(2014) Joanna Kowal et al.   CURRENT OPINION IN CELL BIOLOGY

miR-200–containing extracellular vesicles promote breast cancer cell metastasis

(2014) Minh T.N. Le et al.   JOURNAL OF CLINICAL INVESTIGATION

Increased apoptosis and DNA double-strand breaks in the embryonic mouse brain in response to very low-dose X-rays but not 50 Hz magnetic fields

(2014) S. Saha et al.   Journal of the Royal Society Interface

Particle size distribution of exosomes and microvesicles determined by transmission electron microscopy, flow cytometry, nanoparticle tracking analysis, and resistive pulse sensing

(2014) E. van der Pol et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Exosomes Are Involved in Mediating Radiation Induced Bystander Signaling in Human Keratinocyte Cells

(2014) K. Kumar Jella et al.   RADIATION RESEARCH

MiR-21 is involved in radiation-induced bystander effects

(2014) Shuai Xu et al.   RNA Biology

Ionizing Radiation and Glioblastoma Exosomes: Implications in Tumor Biology and Cell Migration

(2014) W. Tris Arscott et al.   Translational Oncology

Exosomes in cancer development, metastasis, and drug resistance: a comprehensive review

(2013) Asfar S. Azmi et al.   CANCER AND METASTASIS REVIEWS

Body Fluid Exosomes Promote Secretion of Inflammatory Cytokines in Monocytic Cells via Toll-like Receptor Signaling

(2013) Niko P. Bretz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BM mesenchymal stromal cell–derived exosomes facilitate multiple myeloma progression

(2013) Aldo M. Roccaro et al.   JOURNAL OF CLINICAL INVESTIGATION

Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development

(2013) P. Kucharzewska et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exosomal miRNAs as Biomarkers for Prostate Cancer

(2013) Nina Pettersen Hessvik et al.   Frontiers in Genetics

Hypoxic enhancement of exosome release by breast cancer cells

(2012) Hamish W King et al.   BMC CANCER

Toward tailored exosomes: The exosomal tetraspanin web contributes to target cell selection

(2012) Sanyukta Rana et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Cancer Cells Induced to Express Mesenchymal Phenotype Release Exosome-like Extracellular Vesicles Carrying Tissue Factor

(2012) Delphine Garnier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Active Wnt proteins are secreted on exosomes

(2012) Julia Christina Gross et al.   NATURE CELL BIOLOGY

Possible Role of Exosomes Containing RNA in Mediating Nontargeted Effect of Ionizing Radiation

(2012) Ammar H. J. Al-Mayah et al.   RADIATION RESEARCH

Exosomes as intercellular signalosomes and pharmacological effectors

(2011) Michel Record et al.   BIOCHEMICAL PHARMACOLOGY

Exosomes Released by Melanoma Cells Prepare Sentinel Lymph Nodes for Tumor Metastasis

(2011) J. L. Hood et al.   CANCER RESEARCH

Exosomes from ovarian cancer cells induce adipose tissue-derived mesenchymal stem cells to acquire the physical and functional characteristics of tumor-supporting myofibroblasts

(2011) Jung Ah Cho et al.   GYNECOLOGIC ONCOLOGY

Blast-derived microvesicles in sera from patients with acute myeloid leukemia suppress natural killer cell function via membrane-associated transforming growth factor- 1

(2011) M. J. Szczepanski et al.   HAEMATOLOGICA

Exosomes: Small vesicles participating in intercellular communication

(2011) Anna-Kristin Ludwig et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The Influence of Gender- and Age-related Differences in the Radiosensitivity of Hematopoietic Progenitor Cells Detected in Steady-state Human Peripheral Blood

(2011) Kengo KATO et al.   JOURNAL OF RADIATION RESEARCH

Hypoxia triggers a proangiogenic pathway involving cancer cell microvesicles and PAR-2–mediated heparin-binding EGF signaling in endothelial cells

(2011) Katrin J. Svensson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Radiation-Induced Bystander Effects: What Are They, and How Relevant Are They to Human Radiation Exposures?

(2011) Benjamin J. Blyth et al.   RADIATION RESEARCH

Incidence of heart disease in 35,000 women treated with radiotherapy for breast cancer in Denmark and Sweden

(2011) Paul McGale et al.   RADIOTHERAPY AND ONCOLOGY

Effects of Ionizing Radiation on Self-Renewal and Pluripotency of Human Embryonic Stem Cells

(2010) K. D. Wilson et al.   CANCER RESEARCH

Cell Surface Tetraspanin Tspan8 Contributes to Molecular Pathways of Exosome-Induced Endothelial Cell Activation

(2010) I. Nazarenko et al.   CANCER RESEARCH

Ionizing radiation and hematopoietic malignancies: Altering the adaptive landscape

(2010) Courtney J. Fleenor et al.   CELL CYCLE

Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A–C

(2010) Chieh Hsu et al.   JOURNAL OF CELL BIOLOGY

Microvesicles: mediators of extracellular communication during cancer progression

(2010) V. Muralidharan-Chari et al.   JOURNAL OF CELL SCIENCE

Exosomes/microvesicles as a mechanism of cell-to-cell communication

(2010) Giovanni Camussi et al.   KIDNEY INTERNATIONAL

Hypoxic Tumor Cell Modulates Its Microenvironment to Enhance Angiogenic and Metastatic Potential by Secretion of Proteins and Exosomes

(2010) Jung Eun Park et al.   MOLECULAR & CELLULAR PROTEOMICS

Exosomes Communicate Protective Messages during Oxidative Stress; Possible Role of Exosomal Shuttle RNA

(2010) Maria Eldh et al.   PLoS One

TI-VAMP/VAMP7 and VAMP3/cellubrevin: two v-SNARE proteins involved in specific steps of the autophagy/multivesicular body pathways

(2009) Claudio Marcelo Fader et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Fractionated but Not Single-Dose Radiotherapy Induces an Immune-Mediated Abscopal Effect when Combined with Anti-CTLA-4 Antibody

(2009) M. Z. Dewan et al.   CLINICAL CANCER RESEARCH

MicroRNAs: Predictors and modifiers of chemo- and radiotherapy in different tumour types

(2009) Richard Hummel et al.   EUROPEAN JOURNAL OF CANCER

Tumor-Derived Microvesicles Promote Regulatory T Cell Expansion and Induce Apoptosis in Tumor-Reactive Activated CD8+ T Lymphocytes

(2009) E. U. Wieckowski et al.   JOURNAL OF IMMUNOLOGY

Paracrine induction of endothelium by tumor exosomes

(2009) Joshua L Hood et al.   LABORATORY INVESTIGATION

The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins

(2009) Camilla Raiborg et al.   NATURE

Rab27a and Rab27b control different steps of the exosome secretion pathway

(2009) Matias Ostrowski et al.   NATURE CELL BIOLOGY

Multivesicular Endosome Biogenesis in the Absence of ESCRTs

(2009) Susanne Stuffers et al.   TRAFFIC

VAMP-8 segregates mast cell-preformed mediator exocytosis from cytokine trafficking pathways

(2008) N. Tiwari et al.   BLOOD

Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells

(2008) Khalid Al-Nedawi et al.   NATURE CELL BIOLOGY

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

(2008) Johan Skog et al.   NATURE CELL BIOLOGY

Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes

(2008) K. Trajkovic et al.   SCIENCE