Structure Kinetics Relationships and Molecular Dynamics Show Crucial Role for Heterocycle Leaving Group in Irreversible Diacylglycerol Lipase Inhibitors

Title
Structure Kinetics Relationships and Molecular Dynamics Show Crucial Role for Heterocycle Leaving Group in Irreversible Diacylglycerol Lipase Inhibitors
Authors
Keywords
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Journal
JOURNAL OF MEDICINAL CHEMISTRY
Volume 62, Issue 17, Pages 7910-7922
Publisher
American Chemical Society (ACS)
Online
2019-08-23
DOI
10.1021/acs.jmedchem.9b00686

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