Characterization of ANGPTL4 function in macrophages and adipocytes using Angptl4-knockout and Angptl4-hypomorphic mice

Lipoprotein lipase: Biosynthesis, regulatory factors, and its role in atherosclerosis and other diseases

(2018) Ping-Ping He et al.   CLINICA CHIMICA ACTA

Can targeting ANGPTL proteins improve glucose tolerance?

(2018) Brandon S. J. Davies   DIABETOLOGIA

Loss of angiopoietin-like 4 (ANGPTL4) in mice with diet-induced obesity uncouples visceral obesity from glucose intolerance partly via the gut microbiota

(2018) Aafke W. F. Janssen et al.   DIABETOLOGIA

Angiopoietin-like 4 promotes the intracellular cleavage of lipoprotein lipase by PCSK3/furin in adipocytes

(2018) Wieneke Dijk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes

(2018) Viktoria Gusarova et al.   Nature Communications

Brown adipose tissue derived ANGPTL4 controls glucose and lipid metabolism and regulates thermogenesis

(2018) Abhishek K. Singh et al.   Molecular Metabolism

The Forgotten Lipids: Triglycerides, Remnant Cholesterol, and Atherosclerotic Cardiovascular Disease Risk

(2018) Pratik B Sandesara et al.   ENDOCRINE REVIEWS

FeedingAngptl4−/−micetransfat promotes foam cell formation in mesenteric lymph nodes without leading to ascites

(2017) Antwi-Boasiako Oteng et al.   JOURNAL OF LIPID RESEARCH

ANGPTL8 requires ANGPTL3 to inhibit lipoprotein lipase and plasma triglyceride clearance

(2017) Jorge F. Haller et al.   JOURNAL OF LIPID RESEARCH

Autoantibodies against GPIHBP1 as a Cause of Hypertriglyceridemia

(2017) Anne P. Beigneux et al.   NEW ENGLAND JOURNAL OF MEDICINE

ANGPTL8 promotes the ability of ANGPTL3 to bind and inhibit lipoprotein lipase

(2017) Xun Chi et al.   Molecular Metabolism

Regulation of lipid metabolism by angiopoietin-like proteins

(2016) Wieneke Dijk et al.   CURRENT OPINION IN LIPIDOLOGY

Angiopoietin-like 4 promotes intracellular degradation of lipoprotein lipase in adipocytes

(2016) Wieneke Dijk et al.   JOURNAL OF LIPID RESEARCH

ANGPTL4 variants E40K and T266M are associated with lower fasting triglyceride levels and predicts cardiovascular disease risk in Type 2 diabetic Tunisian population

(2016) Kaouthar Abid et al.   Lipids in Health and Disease

Inactivating Variants in ANGPTL4 and Risk of Coronary Artery Disease

(2016) Frederick E. Dewey et al.   NEW ENGLAND JOURNAL OF MEDICINE

ANGPTL4 deficiency in haematopoietic cells promotes monocyte expansion and atherosclerosis progression

(2016) Binod Aryal et al.   Nature Communications

Saturated Fatty Acids Engage an IRE1α-Dependent Pathway to Activate the NLRP3 Inflammasome in Myeloid Cells

(2016) Megan M. Robblee et al.   Cell Reports

The angiopoietin-like protein ANGPTL4 catalyzes unfolding of the hydrolase domain in lipoprotein lipase and the endothelial membrane protein GPIHBP1 counteracts this unfolding

(2016) Simon Mysling et al.   eLife

ANGPTL4 mediates shuttling of lipid fuel to brown adipose tissue during sustained cold exposure

(2015) Wieneke Dijk et al.   eLife

Physiological regulation of lipoprotein lipase

(2014) Sander Kersten   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The GPIHBP1–LPL Complex Is Responsible for the Margination of Triglyceride-Rich Lipoproteins in Capillaries

(2014) Chris N. Goulbourne et al.   Cell Metabolism

Overexpression of Angiopoietin-Like Protein 4 Protects Against Atherosclerosis Development

(2013) Anastasia Georgiadi et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Identification of RIFL, a novel adipocyte-enriched insulin target gene with a role in lipid metabolism

(2012) Gang Ren et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Lipasin, a novel nutritionally-regulated liver-enriched factor that regulates serum triglyceride levels

(2012) Ren Zhang   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Angiopoietin-like 4 (Angptl4) Protein Is a Physiological Mediator of Intracellular Lipolysis in Murine Adipocytes

(2012) Nora E. Gray et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Atypical angiopoietin-like protein that regulates ANGPTL3

(2012) F. Quagliarini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Triglycerides and Heart Disease

(2011) Ira J. Goldberg et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

A conditional knockout resource for the genome-wide study of mouse gene function

(2011) William C. Skarnes et al.   NATURE

GPIHBP1 Is Responsible for the Entry of Lipoprotein Lipase into Capillaries

(2010) Brandon S.J. Davies et al.   Cell Metabolism

Angptl4 Protects against Severe Proinflammatory Effects of Saturated Fat by Inhibiting Fatty Acid Uptake into Mesenteric Lymph Node Macrophages

(2010) Laeticia Lichtenstein et al.   Cell Metabolism

Angiopoietin-like 4 (ANGPTL4, Fasting-induced Adipose Factor) Is a Direct Glucocorticoid Receptor Target and Participates in Glucocorticoid-regulated Triglyceride Metabolism

(2009) Suneil K. Koliwad et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Abnormal Patterns of Lipoprotein Lipase Release into the Plasma in GPIHBP1-deficient Mice

(2008) Michael M. Weinstein et al.   JOURNAL OF BIOLOGICAL CHEMISTRY