Local inhibition of rRNA transcription without nucleolar segregation after targeted ion irradiation of the nucleolus

MST2 kinase suppresses rDNA transcription in response to DNA damage by phosphorylating nucleolar histone H2B

(2018) Dafni Eleftheria Pefani et al.   EMBO JOURNAL

Nucleolus as an emerging hub in maintenance of genome stability and cancer pathogenesis

(2018) Mikael S. Lindström et al.   ONCOGENE

PARP1-dependent recruitment of the FBXL10-RNF68-RNF2 ubiquitin ligase to sites of DNA damage controls H2A.Z loading

(2018) Gergely Rona et al.   eLife

Nucleolus and chromatin

(2018) Christian Schöfer et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Nucleolar residence of the seckel syndrome protein TRAIP is coupled to ribosomal DNA transcription

(2018) Yangzi Chen et al.   NUCLEIC ACIDS RESEARCH

Integrating the genomic architecture of human nucleolar organizer regions with the biophysical properties of nucleoli

(2017) Hazel Mangan et al.   FEBS Journal

Histone demethylase KDM5A regulates the ZMYND8–NuRD chromatin remodeler to promote DNA repair

(2017) Fade Gong et al.   JOURNAL OF CELL BIOLOGY

Meta-analysis of DNA double-strand break response kinetics

(2017) Jakub A. Kochan et al.   NUCLEIC ACIDS RESEARCH

CDYL1 fosters double-strand break-induced transcription silencing and promotes homology-directed repair

(2017) Enas R Abu-Zhayia et al.   Journal of Molecular Cell Biology

A damaged genome’s transcriptional landscape through multilayered expression profiling around in situ-mapped DNA double-strand breaks

(2017) Fabio Iannelli et al.   Nature Communications

A unique enhancer boundary complex on the mouse ribosomal RNA genes persists after loss of Rrn3 or UBF and the inactivation of RNA polymerase I transcription

(2017) Chelsea Herdman et al.   PLoS Genetics

Nucleolar sub-compartments in motion during rRNA synthesis inhibition: Contraction of nucleolar condensed chromatin and gathering of fibrillar centers are concomitant

(2017) Pavel Tchelidze et al.   PLoS One

Nucleolar Reorganization Upon Site-Specific Double-Strand Break Induction

(2016) Michal Franek et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

RNA Processing and Genome Stability: Cause and Consequence

(2016) Vihandha O. Wickramasinghe et al.   MOLECULAR CELL

Fluorescent sensors of PARP-1 structural dynamics and allosteric regulation in response to DNA damage

(2016) Jamin D. Steffen et al.   NUCLEIC ACIDS RESEARCH

A New Nanobody-Based Biosensor to Study Endogenous PARP1 In Vitro and in Live Human Cells

(2016) Andrea Buchfellner et al.   PLoS One

Breaks in the 45S rDNA Lead to Recombination-Mediated Loss of Repeats

(2016) Daniël O. Warmerdam et al.   Cell Reports

Depletion of Histone Demethylase Jarid1A Resulting in Histone Hyperacetylation and Radiation Sensitivity Does Not Affect DNA Double-Strand Break Repair

(2016) Corina Penterling et al.   PLoS One

A localized nucleolar DNA damage response facilitates recruitment of the homology-directed repair machinery independent of cell cycle stage

(2015) Marjolein van Sluis et al.   GENES & DEVELOPMENT

Determination of the accuracy for targeted irradiations of cellular substructures at SNAKE

(2015) C. Siebenwirth et al.   NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS

High levels of TopBP1 induce ATR-dependent shut-down of rRNA transcription and nucleolar segregation

(2015) Miiko Sokka et al.   NUCLEIC ACIDS RESEARCH

Nucleolar responses to DNA double-strand breaks

(2015) Dorthe Helena Larsen et al.   NUCLEIC ACIDS RESEARCH

Live cell imaging at the Munich ion microbeam SNAKE – a status report

(2015) Guido A Drexler et al.   Radiation Oncology

ATM Dependent Silencing Links Nucleolar Chromatin Reorganization to DNA Damage Recognition

(2015) Shane M. Harding et al.   Cell Reports

Polymerase Stalling during Replication, Transcription and Translation

(2014) Ellen R. Edenberg et al.   CURRENT BIOLOGY

The NBS1–Treacle complex controls ribosomal RNA transcription in response to DNA damage

(2014) Dorthe H. Larsen et al.   NATURE CELL BIOLOGY

DNA double-strand breaks promote methylation of histone H3 on lysine 9 and transient formation of repressive chromatin

(2014) M. K. Ayrapetov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA-damage response in chromatin of ribosomal genes and the surrounding genome

(2013) Veronika Foltánková et al.   GENE

DNA damage-induced inhibition of rRNA synthesis by DNA-PK and PARP-1

(2013) Anne S. Calkins et al.   NUCLEIC ACIDS RESEARCH

The nucleolus: an emerging target for cancer therapy

(2013) Nadine Hein et al.   TRENDS IN MOLECULAR MEDICINE

PARP1 Parylation Promotes Silent Locus Transmission in the Nucleolus: The Suspicion Confirmed

(2012) Maxim Isabelle et al.   MOLECULAR CELL

DNAPKcs-dependent arrest of RNA polymerase II transcription in the presence of DNA breaks

(2012) Tibor Pankotai et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Perceptions and Experiences of Research Participants on Gender-Based Violence Community Based Survey: Implications for Ethical Guidelines

(2012) Yandisa Sikweyiya et al.   PLoS One

Double-strand break-induced transcriptional silencing is associated with loss of tri-methylation at H3K4

(2011) Doris M. Seiler et al.   CHROMOSOME RESEARCH

Quantitative Proteomics and Dynamic Imaging of the Nucleolus Reveal Distinct Responses to UV and Ionizing Radiation

(2011) Henna M. Moore et al.   MOLECULAR & CELLULAR PROTEOMICS

Integrative genomic analysis of human ribosomal DNA

(2011) Gabriel E. Zentner et al.   NUCLEIC ACIDS RESEARCH

ATM-Dependent Chromatin Changes Silence Transcription In cis to DNA Double-Strand Breaks

(2010) Niraj M. Shanbhag et al.   CELL

High-resolution profiling of γH2AX around DNA double strand breaks in the mammalian genome

(2010) Jason S Iacovoni et al.   EMBO JOURNAL

The Nucleolus under Stress

(2010) Séverine Boulon et al.   MOLECULAR CELL

Delocalization of nucleolar poly(ADP-ribose) polymerase-1 to the nucleoplasm and its novel link to cellular sensitivity to DNA damage

(2009) Ann Rancourt et al.   DNA REPAIR

The live cell irradiation and observation setup at SNAKE

(2009) V. Hable et al.   NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS

Comparative analysis of different laser systems to study cellular responses to DNA damage in mammalian cells

(2009) Xiangduo Kong et al.   NUCLEIC ACIDS RESEARCH

The Epigenetics of rRNA Genes: From Molecular to Chromosome Biology

(2008) Brian McStay et al.   Annual Review of Cell and Developmental Biology

Formation of Clustered DNA Damage after High-LET Irradiation: A Review

(2008) Megumi HADA et al.   JOURNAL OF RADIATION RESEARCH