Effects of drying method and excipient on structure and stability of protein solids using solid-state hydrogen/deuterium exchange mass spectrometry (ssHDX-MS)

标题
Effects of drying method and excipient on structure and stability of protein solids using solid-state hydrogen/deuterium exchange mass spectrometry (ssHDX-MS)
作者
关键词
Lyophilization, Spray-drying, Protein structure, Biopharmaceutical processing, Formulation, Solid-state hydrogen/deuterium exchange with mass spectrometric analysis (ssHDX-MS)
出版物
INTERNATIONAL JOURNAL OF PHARMACEUTICS
Volume 567, Issue -, Pages 118470
出版商
Elsevier BV
发表日期
2019-06-26
DOI
10.1016/j.ijpharm.2019.118470

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