Zerumbone Suppresses Enterotoxigenic Bacteroides fragilis Infection-Induced Colonic Inflammation through Inhibition of NF-κΒ

Human colon mucosal biofilms from healthy or colon cancer hosts are carcinogenic

(2019) Sarah Tomkovich et al.   JOURNAL OF CLINICAL INVESTIGATION

The emergence of antimicrobial resistance in environmental strains of the Bacteroides fragilis group

(2019) Sebastian Niestępski et al.   ENVIRONMENT INTERNATIONAL

Adaptive Evolution within Gut Microbiomes of Healthy People

(2019) Shijie Zhao et al.   Cell Host & Microbe

Anti-biofilm and antimicrobial effects of zerumbone against Bacteroides fragilis

(2019) Hye-Rim Kim et al.   ANAEROBE

Zerumbone inhibits Candida albicans biofilm formation and hyphal growth

(2019) Da-Seul Shin et al.   CANADIAN JOURNAL OF MICROBIOLOGY

Bacteroides fragilis polysaccharide A induces IL-10 secreting B and T cells that prevent viral encephalitis

(2019) Chandran Ramakrishna et al.   Nature Communications

Partners in crime: neutrophils and monocytes/macrophages in inflammation and disease

(2018) Kathryn Prame Kumar et al.   CELL AND TISSUE RESEARCH

Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells

(2018) Liam Chung et al.   Cell Host & Microbe

Host Nitric Oxide Disrupts Microbial Cell-to-Cell Communication to Inhibit Staphylococcal Virulence

(2018) Rodolfo Urbano et al.   Cell Host & Microbe

Docking studies reveal zerumbone targets β-catenin of the Wnt-β-catenin pathway in breast cancer

(2018) Ayesha Fatima et al.   JOURNAL OF THE SERBIAN CHEMICAL SOCIETY

Patients with familial adenomatous polyposis harbor colonic biofilms containing tumorigenic bacteria

(2018) Christine M. Dejea et al.   SCIENCE

The Immunomodulatory and Anti-Inflammatory Role of Polyphenols

(2018) Nour Yahfoufi et al.   Nutrients

Dynamics of Colon Monocyte and Macrophage Activation During Colitis

(2018) Gareth-Rhys Jones et al.   Frontiers in Immunology

Cognitive impairment by antibiotic-induced gut dysbiosis: Analysis of gut microbiota-brain communication

(2016) Esther E. Fröhlich et al.   BRAIN BEHAVIOR AND IMMUNITY

Redundant Innate and Adaptive Sources of IL17 Production Drive Colon Tumorigenesis

(2016) Franck Housseau et al.   CANCER RESEARCH

Reduction of Murine Colon Tumorigenesis Driven by EnterotoxigenicBacteroides fragilisUsing Cefoxitin Treatment

(2016) Christina E. DeStefano Shields et al.   JOURNAL OF INFECTIOUS DISEASES

The myeloid immune signature of enterotoxigenic Bacteroides fragilis-induced murine colon tumorigenesis

(2016) E Thiele Orberg et al.   Mucosal Immunology

Activation of Bacteroides fragilis toxin by a novel bacterial protease contributes to anaerobic sepsis in mice

(2016) Vivian M Choi et al.   NATURE MEDICINE

Antibiotic-Induced Changes in the Intestinal Microbiota and Disease

(2016) Simone Becattini et al.   TRENDS IN MOLECULAR MEDICINE

Anti-biofilm Activities from Resveratrol against Fusobacterium nucleatum

(2016) Zhiyan He et al.   Frontiers in Microbiology

Recent evolution of antibiotic resistance in the anaerobes as compared to previous decades

(2015) Lyudmila Boyanova et al.   ANAEROBE

Binding Mode Analysis of Zerumbone to Key Signal Proteins in the Tumor Necrosis Factor Pathway

(2015) Ayesha Fatima et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Macrophage and dendritic cell subsets in IBD: ALDH+ cells are reduced in colon tissue of patients with ulcerative colitis regardless of inflammation

(2015) M K Magnusson et al.   Mucosal Immunology

Antimicrobial Susceptibility of Clinical Isolates ofBacteroides fragilisGroup Organisms Recovered from 2009 to 2012 in a Korean Hospital

(2015) Jisook Yim et al.   Annals of Laboratory Medicine

Quantitative Profiling of Colorectal Cancer-Associated Bacteria Reveals Associations between Fusobacterium spp., Enterotoxigenic Bacteroides fragilis (ETBF) and Clinicopathological Features of Colorectal Cancer

(2015) Katie S. Viljoen et al.   PLoS One

Antisecretory, Gastroprotective, Antioxidant and Anti-Helicobcter Pylori Activity of Zerumbone from Zingiber Zerumbet (L.) Smith

(2015) Heyam Mohamed Ali Sidahmed et al.   PLoS One

The Bacteroides fragilis Toxin Gene Is Prevalent in the Colon Mucosa of Colorectal Cancer Patients

(2014) Annemarie Boleij et al.   CLINICAL INFECTIOUS DISEASES

Short-Term Effect of Antibiotics on Human Gut Microbiota

(2014) Suchita Panda et al.   PLoS One

Antibacterial and antimutagenic activities of novel zerumbone analogues

(2013) S.C. Santosh Kumar et al.   FOOD CHEMISTRY

Bactericidal Antibiotics Induce Mitochondrial Dysfunction and Oxidative Damage in Mammalian Cells

(2013) S. Kalghatgi et al.   Science Translational Medicine

Epidemiology of Viral Hepatitis and Hepatocellular Carcinoma

(2012) Hashem B. El-Serag   GASTROENTEROLOGY

Acquired Antibiotic Resistance Genes: An Overview

(2011) Angela H. A. M. van Hoek et al.   Frontiers in Microbiology

Anti-inflammatory effect of zerumbone on acute and chronic inflammation models in mice

(2010) M.R. Sulaiman et al.   FITOTERAPIA

Long-term impacts of antibiotic exposure on the human intestinal microbiota

(2010) C. Jernberg et al.   MICROBIOLOGY-SGM

IL-17 and Th17 Cells

(2009) Thomas Korn et al.   Annual Review of Immunology

Zerumbone Enhances TRAIL-Induced Apoptosis through the Induction of Death Receptors in Human Colon Cancer Cells: Evidence for an Essential Role of Reactive Oxygen Species

(2009) S. Yodkeeree et al.   CANCER RESEARCH

Dangerous liaisons: STAT3 and NF-κB collaboration and crosstalk in cancer

(2009) Sergei I. Grivennikov et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Production of Reactive Oxygen Species Is Turned On and Rapidly Shut Down in Epithelial Cells Infected with Chlamydia trachomatis

(2009) G. Boncompain et al.   INFECTION AND IMMUNITY

Induction of Persistent Colitis by a Human Commensal, Enterotoxigenic Bacteroides fragilis, in Wild-Type C57BL/6 Mice

(2009) K.-J. Rhee et al.   INFECTION AND IMMUNITY

A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses

(2009) Shaoguang Wu et al.   NATURE MEDICINE

The Nuclear Factor NF- B Pathway in Inflammation

(2009) T. Lawrence   Cold Spring Harbor Perspectives in Biology

Zerumbone Down-regulates Chemokine Receptor CXCR4 Expression Leading to Inhibition of CXCL12-Induced Invasion of Breast and Pancreatic Tumor Cells

(2008) Bokyung Sung et al.   CANCER RESEARCH

Association of EnterotoxigenicBacteroides fragilisInfection with Inflammatory Diarrhea

(2008) Cynthia L. Sears et al.   CLINICAL INFECTIOUS DISEASES