The Role of MMP8 in Cancer: A Systematic Review

Serum MMP-8 and TIMP-1 predict prognosis in colorectal cancer

(2018) Camilla Böckelman et al.   BMC CANCER

High-serum MMP-8 levels are associated with decreased survival and systemic inflammation in colorectal cancer

(2018) Päivi Sirniö et al.   BRITISH JOURNAL OF CANCER

The Significance of MMP-1 in EGFR-TKI–Resistant Lung Adenocarcinoma: Potential for Therapeutic Targeting

(2018) Ryoko Saito et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Global surveillance of trends in cancer survival 2000–14 (CONCORD-3): analysis of individual records for 37 513 025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries

(2018) Claudia Allemani et al.   LANCET

Proteins involved in cutaneous basal cell carcinoma development

(2018) Magdalena Ciążyńska et al.   Oncology Letters

Proteomic analyses identify prognostic biomarkers for pancreatic ductal adenocarcinoma

(2018) Dingyuan Hu et al.   Oncotarget

Association of Matrix Metalloproteinase-8 Genotypes with the Risk of Bladder Cancer

(2018) TSUNG-HSUN TSAI et al.   ANTICANCER RESEARCH

Serum MMP-8 and TIMP-1 as prognostic biomarkers in gastric cancer

(2018) Alli Laitinen et al.   TUMOR BIOLOGY

Combined detection of IL-6 and IL-8 is beneficial to the diagnosis of early stage esophageal squamous cell cancer: a preliminary study based on the screening of serum markers using protein chips

(2018) Qiang Tong et al.   OncoTargets and Therapy

Antitumor and anti-metastatic mechanisms of Rhizoma paridis saponins in Lewis mice

(2017) Shuli Man et al.   ENVIRONMENTAL TOXICOLOGY

Polymorphisms in matrix metalloproteinases 2, 3, and 8 increase recurrence and mortality risk by regulating enzyme activity in gastric adenocarcinoma

(2017) Youdong Lin et al.   Oncotarget

Differential expression of CD44 and CD24 markers discriminates the epitheliod from the fibroblastoid subset in a sarcomatoid renal carcinoma cell line: evidence suggesting the existence of cancer stem cells in both subsets as studied with sorted cells

(2017) Chin-Hsuan Hsieh et al.   Oncotarget

The impact of human adipose tissue-derived stem cells on breast cancer cells: implications for cell-assisted lipotransfers in breast reconstruction

(2017) Eva Koellensperger et al.   Stem Cell Research & Therapy

Human neutrophil peptide-1 affects matrix metalloproteinase-2, -8 and -9 secretions of oral squamous cell carcinoma cell lines in vitro

(2016) Ahmed Ali Musrati et al.   ARCHIVES OF ORAL BIOLOGY

Reciprocal activation between MMP-8 and TGF-β1 stimulates EMT and malignant progression of hepatocellular carcinoma

(2016) Guihui Qin et al.   CANCER LETTERS

Seesaw of matrix metalloproteinases (MMPs)

(2016) Charu Kapoor et al.   Journal of Cancer Research and Therapeutics

Neutrophils Suppress Intraluminal NK Cell-Mediated Tumor Cell Clearance and Enhance Extravasation of Disseminated Carcinoma Cells

(2016) A. Spiegel et al.   Cancer Discovery

Systemic matrix metalloproteinase-8 response in chronic tonsillitis

(2016) Taru Ilmarinen et al.   Infectious Diseases

Profile of MMP and TIMP Expression in Human Pancreatic Stellate Cells: Regulation by IL-1α and TGFβ and Implications for Migration of Pancreatic Cancer Cells

(2016) Vegard Tjomsland et al.   NEOPLASIA

Is England closing the international gap in cancer survival?

(2015) Sarah Walters et al.   BRITISH JOURNAL OF CANCER

Trends in the lifetime risk of developing cancer in Great Britain: comparison of risk for those born from 1930 to 1960

(2015) A S Ahmad et al.   BRITISH JOURNAL OF CANCER

DNA-PKcs plays role in cancer metastasis through regulation of secreted proteins involved in migration and invasion

(2015) Ewa Kotula et al.   CELL CYCLE

Differences in the whole saliva baseline proteome profile associated with development of oral mucositis in head and neck cancer patients undergoing radiotherapy

(2015) Nico Jehmlich et al.   Journal of Proteomics

Analysis of matrix metalloproteinases, especially MMP-8, in gingival crevicular fluid, mouthrinse and saliva for monitoring periodontal diseases

(2015) Timo Sorsa et al.   PERIODONTOLOGY 2000

Molecular profiling of peripheral blood is associated with circulating tumor cells content and poor survival in metastatic castration-resistant prostate cancer

(2015) Mercedes Marín-Aguilera et al.   Oncotarget

MMP-7, MMP-8, and MMP-9 in oral and cutaneous squamous cell carcinomas

(2015) Abdirisak Ahmed Haji Omar et al.   Oral Surgery Oral Medicine Oral Pathology Oral Radiology

The Regulation of Matrix Metalloproteinase Expression and the Role of Discoidin Domain Receptor 1/2 Signalling in Zoledronate-treated PC3 Cells

(2015) Buket Reel et al.   Journal of Cancer

Technical Review:In SituHybridization

(2014) Ellen Jensen   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Carotid Body Paragangliomas and Matrix Metalloproteinases

(2014) Raffaele Serra et al.   ANNALS OF VASCULAR SURGERY

Chemically Synthesized Matrix Metalloproteinase and Angiogenesis-inhibiting Peptides as Anticancer Agents

(2014) Jialiang Hu et al.   Anti-Cancer Agents in Medicinal Chemistry

Serpin peptidase inhibitor clade A member 1 is a biomarker of poor prognosis in gastric cancer

(2014) C H Kwon et al.   BRITISH JOURNAL OF CANCER

Benefit of adjuvant interferon alfa-2b (IFN-α) therapy in melanoma patients with high serum MMP-8 levels

(2014) Pia Vihinen et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Expression of the Matrix Metalloproteases 2, 14, 24, and 25 and Tissue Inhibitor 3 as Potential Molecular Markers in Advanced Human Gastric Cancer

(2014) Sol de la Peña et al.   DISEASE MARKERS

Matrix metalloproteinase-8 promoter gene polymorphisms in Mexican women with ovarian cancer

(2014) Fabian Arechavaleta-Velasco et al.   MEDICAL ONCOLOGY

Resection of Carotid Body Tumors reduces arterial blood pressure. An underestimated neuroendocrine syndrome

(2014) Stefano de Franciscis et al.   International Journal of Surgery

Prognostic value of serum MMP-8, -9 and TIMP-1 in patients with hepatocellular carcinoma

(2013) Marko Lempinen et al.   ANNALS OF MEDICINE

Generation of antitumor peptides by connection of matrix metalloproteinase-9 peptide inhibitor to an endostatin fragment

(2013) Zheng Qiu et al.   ANTI-CANCER DRUGS

Arylamino methylene bisphosphonate derivatives as bone seeking matrix metalloproteinase inhibitors

(2013) Marilena Tauro et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Expression of Matrix Metalloproteinases in Human Breast Cancer Tissues

(2013) Chellakkan Selvanesan Benson et al.   DISEASE MARKERS

Clostridium butyricum MIYAIRI 588 shows antitumor effects by enhancing the release of TRAIL from neutrophils through MMP-8

(2013) MASAHIDE SHINNOH et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Matrix Metalloproteinase 8 (Collagenase 2) Induces the Expression of Interleukins 6 and 8 in Breast Cancer Cells

(2013) Sally Thirkettle et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulatory expression of MMP-8/MMP-9 and inhibition of proliferation, migration and invasion in human lung cancer A549 cells in the presence of HGF variants

(2013) Rakesh Ramanujum et al.   KAOHSIUNG JOURNAL OF MEDICAL SCIENCES

Functional polymorphisms of matrix metalloproteinase-9 and survival in patients with locoregionally advanced nasopharyngeal carcinoma treated with chemoradiotherapy

(2013) Huai Liu et al.   MEDICAL ONCOLOGY

Genetic variants in matrix metalloproteinase genes as disposition factors for ovarian cancer risk, survival, and clinical outcome

(2013) Yan Wang et al.   MOLECULAR CARCINOGENESIS

The anti-metastatic activity of collagenase-2 in breast cancer cells is mediated by a signaling pathway involving decorin and miR-21

(2013) C Soria-Valles et al.   ONCOGENE

Inhibition of tumor growth and metastasis by a self-therapeutic nanoparticle

(2013) R. R. Arvizo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Target fishing and docking studies of the novel derivatives of aryl-aminopyridines with potential anticancer activity

(2012) Slavica Erić et al.   BIOORGANIC & MEDICINAL CHEMISTRY

MMP inhibition by barbiturate homodimers

(2012) Jun Wang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Immature myeloid cells derived from mouse placentas and malignant tumors demonstrate similar proangiogenic transcriptional signatures

(2012) Ofer Fainaru et al.   FERTILITY AND STERILITY

Replication study for reported SNP associations with breast cancer survival

(2012) Alicia Beeghly-Fadiel et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

A functional genetic screen reveals new regulators of  1-integrin activity

(2012) T. Pellinen et al.   JOURNAL OF CELL SCIENCE

Serum CA19-9, cathepsin D, and matrix metalloproteinase-7 as a diagnostic panel for pancreatic ductal adenocarcinoma

(2012) Hyung-Doo Park et al.   PROTEOMICS

Production of Tissue Microarrays, Immunohistochemistry Staining and Digitalization Within the Human Protein Atlas

(2012) Caroline Kampf et al.   Jove-Journal of Visualized Experiments

Biphenyl Sulfonylamino Methyl Bisphosphonic Acids as Inhibitors of Matrix Metalloproteinases and Bone Resorption

(2011) Maria Teresa Rubino et al.   ChemMedChem

Uncommon GNAQ, MMP8, AKT3, EGFR, and PIK3R1 Mutations in Thyroid Cancers

(2011) Avaniyapuram Kannan Murugan et al.   ENDOCRINE PATHOLOGY

Synthesis and biological evaluation in U87MG glioma cells of (ethynylthiophene)sulfonamido-based hydroxamates as matrix metalloproteinase inhibitors

(2011) Elisa Nuti et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A mechanism of apigenin-induced apoptosis is potentially related to anti-angiogenesis and anti-migration in human hepatocellular carcinoma cells

(2011) Bo Ra Kim et al.   FOOD AND CHEMICAL TOXICOLOGY

MDSC as a mechanism of tumor escape from sunitinib mediated anti-angiogenic therapy

(2011) James Finke et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Serum MMP-8 levels increase in colorectal cancer and correlate with disease course and inflammatory properties of primary tumors

(2011) Juha P. Väyrynen et al.   INTERNATIONAL JOURNAL OF CANCER

Modulation of migratory activity and invasiveness of human glioma spheroids following 5-aminolevulinic acid–based photodynamic treatment

(2011) Nima Etminan et al.   JOURNAL OF NEUROSURGERY

Prognostic significance of matrix metalloproteinase-2, -8, -9, and -13 in oral tongue cancer

(2011) Laura K. Mäkinen et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Association of MMP8 gene variation with an increased risk of malignant melanoma

(2011) Tadeusz Dębniak et al.   MELANOMA RESEARCH

Relaxin Enhances the Collagenolytic Activity and In Vitro Invasiveness by Upregulating Matrix Metalloproteinases in Human Thyroid Carcinoma Cells

(2011) J. Bialek et al.   MOLECULAR CANCER RESEARCH

Type I and III collagen degradation products in serum predict patient survival in head and neck squamous cell carcinoma

(2011) Sini Nurmenniemi et al.   ORAL ONCOLOGY

Surveying proteolytic processes in human cancer microenvironments by microdialysis and activity-based mass spectrometry

(2011) Markus Hardt et al.   Proteomics Clinical Applications

Association of single nucleotide polymorphisms in promoter of matrix metalloproteinase-2, 8 genes with bladder cancer risk in Northern India

(2011) Priyanka Srivastava et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Comparison of metalloproteinase protein and activity profiling

(2010) Orsi Giricz et al.   ANALYTICAL BIOCHEMISTRY

Matrix metalloproteinase 8 deficiency in mice exacerbates inflammatory arthritis through delayed neutrophil apoptosis and reduced caspase 11 expression

(2010) Jennifer H. Cox et al.   ARTHRITIS AND RHEUMATISM

A multiplexed, particle-based flow cytometric assay identified plasma matrix metalloproteinase-7 to be associated with cancer-related death among patients with bladder cancer

(2010) Robert S. Svatek et al.   CANCER

A novel and selective membrane type-1 matrix metalloproteinase (MT1-MMP) inhibitor reduces cancer cell motility and tumor growth

(2010) Juho Suojanen et al.   CANCER BIOLOGY & THERAPY

Ultrasound-guided intratumoral administration of collagenase-2 improved liposome drug accumulation in solid tumor xenografts

(2010) Xiangpeng Zheng et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Microarray-based Transcriptional and Epigenetic Profiling of Matrix Metalloproteinases, Collagens, and Related Genes in Cancer

(2010) Andrei V. Chernov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential matrix metalloproteinase levels in adenocarcinoma and squamous cell carcinoma of the lung

(2010) Sonam A. Shah et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Plasma level of tissue inhibitor of matrix metalloproteinase-1 but not that of matrix metalloproteinase-8 predicts survival in head and neck squamous cell cancer

(2010) Pratikshya Pradhan-Palikhe et al.   ORAL ONCOLOGY

Expression of matrix metalloproteinases-2, -8, -13, -26, and tissue inhibitors of metalloproteinase-1 in human osteosarcoma

(2010) Jarkko T. Korpi et al.   SURGICAL ONCOLOGY-OXFORD

CCL25-CCR9 interaction modulates ovarian cancer cell migration, metalloproteinase expression, and invasion

(2010) Erica L Johnson et al.   World Journal of Surgical Oncology

Polymorphism +17 C/G in Matrix Metalloprotease MMP8 decreases lung cancer risk

(2009) Patricia González-Arriaga et al.   BMC CANCER

Expression of matrix metalloproteinases (MMPs) in primary human breast cancer and breast cancer cell lines: New findings and review of the literature

(2009) Andrea Köhrmann et al.   BMC CANCER

Common Genetic Variation in Candidate Genes and Susceptibility to Subtypes of Breast Cancer

(2009) N. Mavaddat et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Suppression of gastric cancer dissemination by ephrin-B1-derived peptide

(2009) Masamitsu Tanaka et al.   CANCER SCIENCE

Elevated intraperitoneal matrix metalloproteinases-8 and -9 in patients who develop anastomotic leakage after rectal cancer surgery: a pilot study

(2009) Björn Pasternak et al.   Colorectal Disease

Matrix Metalloproteinases As Novel Biomarker s and Potential Therapeutic Targets in Human Cancer

(2009) Roopali Roy et al.   JOURNAL OF CLINICAL ONCOLOGY

Matrix metalloproteinase-26 is present more frequently in squamous cell carcinomas of immunosuppressed compared with immunocompetent patients

(2009) Tiina Kuivanen et al.   JOURNAL OF CUTANEOUS PATHOLOGY

Serum matrix metalloproteinase-8 is associated with ulceration and vascular invasion of malignant melanoma

(2009) Pia Vihinen et al.   MELANOMA RESEARCH

Analysis of the matrix metalloproteinase family reveals that MMP8 is often mutated in melanoma

(2009) Lavanya H Palavalli et al.   NATURE GENETICS

C-C Chemokine Receptor 5 on Pulmonary Fibrocytes Facilitates Migration and Promotes Metastasis via Matrix Metalloproteinase 9

(2008) Hendrik W. van Deventer et al.   AMERICAN JOURNAL OF PATHOLOGY

Matrix metalloproteinase expression and outcome in patients with breast cancer: analysis of a published database

(2008) P. M. McGowan et al.   ANNALS OF ONCOLOGY

Plasma MMP1 and MMP8 expression in breast cancer: Protective role of MMP8 against lymph node metastasis

(2008) Julie Decock et al.   BMC CANCER

Collagenase-2 (matrix metalloproteinase-8) plays a protective role in tongue cancer

(2008) J T Korpi et al.   BRITISH JOURNAL OF CANCER

No Association of MMP-7, MMP-8, and MMP-21 Polymorphisms with the Risk of Hepatocellular Carcinoma in a Chinese Population

(2008) W. Qiu et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Missense Polymorphisms in Matrix Metalloproteinase Genes and Skin Cancer Risk

(2008) H. Nan et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Matrix Metalloproteinase-8 Functions as a Metastasis Suppressor through Modulation of Tumor Cell Adhesion and Invasion

(2008) A. Gutierrez-Fernandez et al.   CANCER RESEARCH

MMP-13 is over-expressed in renal cell carcinoma bone metastasis and is induced by TGF-β1

(2008) Scott L. Kominsky et al.   CLINICAL & EXPERIMENTAL METASTASIS

Progesterone receptor modulator CDB-2914 induces extracellular matrix metalloproteinase inducer in cultured human uterine leiomyoma cells

(2008) Q. Xu et al.   MOLECULAR HUMAN REPRODUCTION