DNA-PKcs plays role in cancer metastasis through regulation of secreted proteins involved in migration and invasion

DNA Damage Triggers Golgi Dispersal via DNA-PK and GOLPH3

(2014) Suzette E. Farber-Katz et al.   CELL

A Preclinical Study Combining the DNA Repair Inhibitor Dbait with Radiotherapy for the Treatment of Melanoma

(2014) Julian Biau et al.   NEOPLASIA

Inhibition of Snail1-DNA-PKcs Protein-Protein Interface Sensitizes Cancer Cells and Inhibits Tumor Metastasis

(2013) Ga-Young Kang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Should Cytoreductive Treatment Be Performed Before Transplantation in Patients With High-Risk Myelodysplastic Syndrome?

(2013) Emilio Paolo Alessandrino et al.   JOURNAL OF CLINICAL ONCOLOGY

DNA-PK Target Identification Reveals Novel Links between DNA Repair Signaling and Cytoskeletal Regulation

(2013) Ewa Kotula et al.   PLoS One

Role of MRE11 in Cell Proliferation, Tumor Invasion, and DNA Repair in Breast Cancer

(2012) Shyng-Shiou F. Yuan et al.   JNCI-Journal of the National Cancer Institute

Recognition, signaling, and repair of DNA double-strand breaks produced by ionizing radiation in mammalian cells: The molecular choreography

(2012) Larry H. Thompson   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

DNAPKcs-dependent arrest of RNA polymerase II transcription in the presence of DNA breaks

(2012) Tibor Pankotai et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Low doses ionizing radiation enhances the invasiveness of breast cancer cells by inducing epithelial–mesenchymal transition

(2011) Xin Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Roles of Tumor-Derived Exosomes in Cancer Pathogenesis

(2011) Chenjie Yang et al.   Clinical & Developmental Immunology

Ionizing Radiation Promotes Migration and Invasion of Cancer Cells Through Transforming Growth Factor-Beta–Mediated Epithelial–Mesenchymal Transition

(2011) Yong-Chun Zhou et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Involvement of DNA-dependent Protein Kinase in Normal Cell Cycle Progression through Mitosis

(2011) Kyung-Jong Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A novel role for BRCA1 in regulating breast cancer cell spreading and motility

(2011) Elisabeth D. Coene et al.   JOURNAL OF CELL BIOLOGY

Poly(ADP-ribose)-dependent regulation of Snail1 protein stability

(2011) M I Rodríguez et al.   ONCOGENE

The Effect of a DNA Repair Gene on Cellular Invasiveness: Xrcc3 Over-Expression in Breast Cancer Cells

(2011) Veronica L. Martinez-Marignac et al.   PLoS One

Therapeutic approach of human peritoneal carcinomatosis with Dbait in combination with capnoperitoneum: proof of concept

(2011) Wiebke Solass et al.   SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES

A Role of DNA-PK for the Metabolic Gene Regulation in Response to Insulin

(2009) Roger H.F. Wong et al.   CELL

Small-Molecule Drugs Mimicking DNA Damage: A New Strategy for Sensitizing Tumors to Radiotherapy

(2009) M. Quanz et al.   CLINICAL CANCER RESEARCH

The human telomerase RNA component, hTR, activates the DNA-dependent protein kinase to phosphorylate heterogeneous nuclear ribonucleoprotein A1

(2009) N. S. Y. Ting et al.   NUCLEIC ACIDS RESEARCH

Hyperactivation of DNA-PK by Double-Strand Break Mimicking Molecules Disorganizes DNA Damage Response

(2009) Maria Quanz et al.   PLoS One

DNA Damage Repair and Response Proteins as Targets for Cancer Therapy

(2008) Howard Lieberman   CURRENT MEDICINAL CHEMISTRY

Comparison of nonhomologous end joining and homologous recombination in human cells

(2008) Z MAO et al.   DNA REPAIR

Basement Membrane Derived Fibulin-1 and Fibulin-5 Function as Angiogenesis Inhibitors and Suppress Tumor Growth

(2008) Liang Xie et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Secretion of active membrane type 1 matrix metalloproteinase (MMP-14) into extracellular space in microvesicular exosomes

(2008) Juha Hakulinen et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Differential expression of S100 protein subtypes in malignant melanoma, and benign and malignant peripheral nerve sheath tumors

(2008) Daisuke Nonaka et al.   JOURNAL OF CUTANEOUS PATHOLOGY

The Catalytic Subunit of DNA-Dependent Protein Kinase Regulates Proliferation, Telomere Length, and Genomic Stability in Human Somatic Cells

(2008) B. L. Ruis et al.   MOLECULAR AND CELLULAR BIOLOGY

Overexpression of DNA repair genes is associated with metastasis: A new hypothesis

(2008) A SARASIN et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH