Combined Treatment with L-Carnitine and Nicotinamide Riboside Improves Hepatic Metabolism and Attenuates Obesity and Liver Steatosis

Oxidative Stress and Antioxidant Biomarkers in Clinical and Experimental Models of Non-Alcoholic Fatty Liver Disease

(2019) Ayokanmi Ore et al.   Medicina-Lithuania

Effect of lifelong carnitine supplementation on plasma and tissue carnitine status, hepatic lipid metabolism and stress signalling pathways and skeletal muscle transcriptome in mice at advanced age

(2019) Uzman B. Cheema et al.   BRITISH JOURNAL OF NUTRITION

A randomized placebo-controlled clinical trial of nicotinamide riboside in obese men: safety, insulin-sensitivity, and lipid-mobilizing effects

(2018) Ole L Dollerup et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

NAD + Intermediates: The Biology and Therapeutic Potential of NMN and NR

(2018) Jun Yoshino et al.   Cell Metabolism

SCAP/SREBPs are Central Players in Lipid Metabolism and Novel Metabolic Targets in Cancer Therapy

(2018) Xiang Cheng et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Disorders of mitochondrial long-chain fatty acid oxidation and the carnitine shuttle

(2018) Suzan J. G. Knottnerus et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults

(2018) Christopher R. Martens et al.   Nature Communications

Sirt2 facilitates hepatic glucose uptake by deacetylating glucokinase regulatory protein

(2018) Hitoshi Watanabe et al.   Nature Communications

Key Inflammatory Processes in Human NASH Are Reflected in Ldlr−/−.Leiden Mice: A Translational Gene Profiling Study

(2018) Martine C. Morrison et al.   Frontiers in Physiology

Dietary Isoliquiritigenin at a Low Dose Ameliorates Insulin Resistance and NAFLD in Diet-Induced Obesity in C57BL/6J Mice

(2018) Youngmi Lee et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Effects of a wide range of dietary nicotinamide riboside (NR) concentrations on metabolic flexibility and white adipose tissue (WAT) of mice fed a mildly obesogenic diet

(2017) Wenbiao Shi et al.   MOLECULAR NUTRITION & FOOD RESEARCH

A casein hydrolysate based formulation attenuates obesity and associated non-alcoholic fatty liver disease and atherosclerosis in LDLr-/-.Leiden mice

(2017) Marieke H. Schoemaker et al.   PLoS One

Evaluation of the effects of L-carnitine on medaka (Oryzias latipes) fatty liver

(2017) Koichi Fujisawa et al.   Scientific Reports

Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes

(2016) Zobair M. Younossi et al.   HEPATOLOGY

Comment on ‘The effect of (l-)carnitine on weight loss in adults: a systematic review and meta-analysis of randomized controlled trials’

(2016) F. B. Del Vecchio et al.   Obesity Reviews

Probability of an Obese Person Attaining Normal Body Weight: Cohort Study Using Electronic Health Records

(2015) Alison Fildes et al.   AMERICAN JOURNAL OF PUBLIC HEALTH

Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice

(2015) Karim Gariani et al.   HEPATOLOGY

Peroxisome-mitochondria interplay and disease

(2015) Michael Schrader et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Physiological and pathophysiological roles of NAMPT and NAD metabolism

(2015) Antje Garten et al.   Nature Reviews Endocrinology

Role of lipid peroxidation derived 4-hydroxynonenal (4-HNE) in cancer: Focusing on mitochondria

(2015) Huiqin Zhong et al.   Redox Biology

Anacetrapib reduces progression of atherosclerosis, mainly by reducing non-HDL-cholesterol, improves lesion stability and adds to the beneficial effects of atorvastatin

(2014) S. Kuhnast et al.   EUROPEAN HEART JOURNAL

Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013

(2014) Marie Ng et al.   LANCET

L-Carnitine Prevents Progression of Non-Alcoholic Steatohepatitis in a Mouse Model with Upregulation of Mitochondrial Pathway

(2014) Hisashi Ishikawa et al.   PLoS One

Establishment of a General NAFLD Scoring System for Rodent Models and Comparison to Human Liver Pathology

(2014) Wen Liang et al.   PLoS One

Coordinated and Interactive Expression of Genes of Lipid Metabolism and Inflammation in Adipose Tissue and Liver during Metabolic Overload

(2013) Wen Liang et al.   PLoS One

The NAD+ Precursor Nicotinamide Riboside Enhances Oxidative Metabolism and Protects against High-Fat Diet-Induced Obesity

(2012) Carles Cantó et al.   Cell Metabolism

Transfer of metabolites across the peroxisomal membrane

(2011) Vasily D. Antonenkov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mitochondrial dysfunction in obesity

(2011) Juan C Bournat et al.   Current Opinion in Endocrinology Diabetes and Obesity

l-Carnitine Supplementation to Diet: A New Tool in Treatment of Nonalcoholic Steatohepatitis—A Randomized and Controlled Clinical Trial

(2010) Mariano Malaguarnera et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Increased Levels of Plasma Acylcarnitines in Obesity and Type 2 Diabetes and Identification of a Marker of Glucolipotoxicity

(2010) Stephanie J. Mihalik et al.   Obesity

Medium Chain Acylcarnitines Dominate the Metabolite Pattern in Humans under Moderate Intensity Exercise and Support Lipid Oxidation

(2010) Rainer Lehmann et al.   PLoS One

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

Integrated, Nontargeted Ultrahigh Performance Liquid Chromatography/Electrospray Ionization Tandem Mass Spectrometry Platform for the Identification and Relative Quantification of the Small-Molecule Complement of Biological Systems

(2009) Anne M. Evans et al.   ANALYTICAL CHEMISTRY

Acyl-CoA synthesis, lipid metabolism and lipotoxicity

(2009) Lei O. Li et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Ameliorating Hypertension and Insulin Resistance in Subjects at Increased Cardiovascular Risk

(2009) Piero Ruggenenti et al.   HYPERTENSION

Carnitine Insufficiency Caused by Aging and Overnutrition Compromises Mitochondrial Performance and Metabolic Control

(2009) Robert C. Noland et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance

(2008) Timothy R. Koves et al.   Cell Metabolism