Challenges in Exosome Isolation and Analysis in Health and Disease

Ionizing radiation affects the composition of the proteome of extracellular vesicles released by head-and-neck cancer cells in vitro

(2019) Agata Abramowicz et al.   JOURNAL OF RADIATION RESEARCH

Optimization of cell culture conditions for exosome isolation using mini-size exclusion chromatography (mini-SEC)

(2019) Nils Ludwig et al.   EXPERIMENTAL CELL RESEARCH

Tumor-derived exosomes promote carcinogenesis of murine oral squamous cell carcinoma

(2019) Beatrice M Razzo et al.   CARCINOGENESIS

Comparison of commercial exosome isolation kits for circulating exosomal microRNA profiling

(2018) Meng Ding et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Exosomes secreted by hypoxic cardiosphere-derived cells enhance tube formation and increase pro-angiogenic miRNA

(2018) Helia Namazi et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Comparison of membrane affinity-based method with size-exclusion chromatography for isolation of exosome-like vesicles from human plasma

(2018) Ruzena Stranska et al.   Journal of Translational Medicine

Low-level laser irradiation at a high power intensity increased human endothelial cell exosome secretion via Wnt signaling

(2018) Hesam Saghaei Bagheri et al.   LASERS IN MEDICAL SCIENCE

Exosomes as a liquid biopsy for lung cancer

(2018) Shaohua Cui et al.   LUNG CANCER

Chemotherapy induces secretion of exosomes loaded with heparanase that degrades extracellular matrix and impacts tumor and host cell behavior

(2018) Shyam K. Bandari et al.   MATRIX BIOLOGY

Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation

(2018) Haiying Zhang et al.   NATURE CELL BIOLOGY

Exosome markers associated with immune activation and oxidative stress in HIV patients on antiretroviral therapy

(2018) Sukrutha Chettimada et al.   Scientific Reports

High-throughput screening identified selective inhibitors of exosome biogenesis and secretion: A drug repurposing strategy for advanced cancer

(2018) Amrita Datta et al.   Scientific Reports

Antiretroviral Drugs Alter the Content of Extracellular Vesicles from HIV-1-Infected Cells

(2018) Catherine DeMarino et al.   Scientific Reports

Isolation of Extracellular Vesicles: General Methodologies and Latest Trends

(2018) Maria Yu. Konoshenko et al.   Biomed Research International

Exosomes from HNSCC Promote Angiogenesis through Reprogramming of Endothelial Cells

(2018) Nils Ludwig et al.   MOLECULAR CANCER RESEARCH

Chemotherapy elicits pro-metastatic extracellular vesicles in breast cancer models

(2018) Ioanna Keklikoglou et al.   NATURE CELL BIOLOGY

Harmonization of exosome isolation from culture supernatants for optimized proteomics analysis

(2018) Agata Abramowicz et al.   PLoS One

Altered cargo proteins of human plasma endothelial cell–derived exosomes in atherosclerotic cerebrovascular disease

(2017) Edward J. Goetzl et al.   FASEB JOURNAL

Comparison of isolation methods of exosomes and exosomal RNA from cell culture medium and serum

(2017) Yue-Ting Tang et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Bone Marrow Mesenchymal Stem Cell-Derived CD63+ Exosomes Transport Wnt3a Exteriorly and Enhance Dermal Fibroblast Proliferation, Migration, and Angiogenesis In Vitro

(2017) Jeffrey D. McBride et al.   STEM CELLS AND DEVELOPMENT

Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA

(2017) Andrea Németh et al.   Scientific Reports

Radiation alters the cargo of exosomes released from squamous head and neck cancer cells to promote migration of recipient cells

(2017) Lisa Mutschelknaus et al.   Scientific Reports

Introduction to Extracellular Vesicles: Biogenesis, RNA Cargo Selection, Content, Release, and Uptake

(2016) Erik R. Abels et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Stimulating the Release of Exosomes Increases the Intercellular Transfer of Prions

(2016) Belinda B. Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxidative stress in retinal pigment epithelium cells increases exosome secretion and promotes angiogenesis in endothelial cells

(2016) Sandra Atienzar-Aroca et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The Influence of Ionizing Radiation on Exosome Composition, Secretion and Intercellular Communication

(2016) Karol Jelonek et al.   PROTEIN AND PEPTIDE LETTERS

Fetal Bovine Serum RNA Interferes with the Cell Culture derived Extracellular RNA

(2016) Zhiyun Wei et al.   Scientific Reports

Mesenchymal Stem Cell-Derived Extracellular Vesicles Promote Angiogenesis: Potencial Clinical Application

(2016) Consuelo Merino-González et al.   Frontiers in Physiology

The potential of tumor-derived exosomes for noninvasive cancer monitoring

(2015) Theresa L Whiteside   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Exosomes in fetal bovine serum dampen primary macrophage IL-1β response to lipopolysaccharide (LPS) challenge

(2015) Lida A. Beninson et al.   IMMUNOLOGY LETTERS

The Effect of Glucose on the Release and Bioactivity of Exosomes From First Trimester Trophoblast Cells

(2015) Gregory E. Rice et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Glucose Starvation in Cardiomyocytes Enhances Exosome Secretion and Promotes Angiogenesis in Endothelial Cells

(2015) Nahuel A. Garcia et al.   PLoS One

Exosomes isolated from plasma of glioma patients enrolled in a vaccination trial reflect antitumor immune activity and might predict survival

(2015) Laurent Muller et al.   OncoImmunology

Extracellular membrane vesicles secreted by mycoplasma Acholeplasma laidlawii PG8 are enriched in virulence proteins

(2014) Vladislav M. Chernov et al.   Journal of Proteomics

Isolation and Characterization of CD34+ Blast-Derived Exosomes in Acute Myeloid Leukemia

(2014) Chang Sook Hong et al.   PLoS One

Plasma Exosomes as Markers of Therapeutic Response in Patients with Acute Myeloid Leukemia

(2014) Chang-Sook Hong et al.   Frontiers in Immunology

Comparison of serum exosome isolation methods for microRNA profiling

(2013) Kadri Rekker et al.   CLINICAL BIOCHEMISTRY

Heparanase Regulates Secretion, Composition, and Function of Tumor Cell-derived Exosomes

(2013) Camilla A. Thompson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biogenesis of extracellular vesicles (EV): exosomes, microvesicles, retrovirus-like vesicles, and apoptotic bodies

(2013) Johnny C. Akers et al.   JOURNAL OF NEURO-ONCOLOGY

Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development

(2013) P. Kucharzewska et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exosomes Released from Mycoplasma Infected Tumor Cells Activate Inhibitory B Cells

(2012) Chenjie Yang et al.   PLoS One

Chemokine-Containing Exosomes Are Released from Heat-Stressed Tumor Cells via Lipid Raft-Dependent Pathway and Act as Efficient Tumor Vaccine

(2011) T. Chen et al.   JOURNAL OF IMMUNOLOGY

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

(2008) Johan Skog et al.   NATURE CELL BIOLOGY