Essential thrombocytosis attributed to JAK2-T875N germline mutation

Mutational subtypes of JAK2 and CALR correlate with different clinical features in Japanese patients with myeloproliferative neoplasms

(2018) Kyohei Misawa et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Polycythemia vera and essential thrombocythemia: 2019 update on diagnosis, risk-stratification and management

(2018) Ayalew Tefferi et al.   AMERICAN JOURNAL OF HEMATOLOGY

Optic nerve astrocyte reactivity protects function in experimental glaucoma and other nerve injuries

(2017) Daniel Sun et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A novel activating, germline JAK2 mutation, JAK2R564Q, causes familial essential thrombocytosis

(2014) S. L. Etheridge et al.   BLOOD

Germ-line JAK2 mutations in the kinase domain are responsible for hereditary thrombocytosis and are resistant to JAK2 and HSP90 inhibitors

(2014) C. Marty et al.   BLOOD

Therapeutic Retrobulbar Inhibition of STAT3 Protects Ischemic Retina Ganglion Cells

(2014) Mansin Wong et al.   MOLECULAR NEUROBIOLOGY

Impact of isolated germline JAK2V617I mutation on human hematopoiesis

(2013) A. J. Mead et al.   BLOOD

Somatic CALR Mutations in Myeloproliferative Neoplasms with Nonmutated JAK2

(2013) J. Nangalia et al.   NEW ENGLAND JOURNAL OF MEDICINE

Somatic Mutations of Calreticulin in Myeloproliferative Neoplasms

(2013) Thorsten Klampfl et al.   NEW ENGLAND JOURNAL OF MEDICINE

Engineered human Tmpk fused with truncated cell-surface markers: versatile cell-fate control safety cassettes

(2012) M Scaife et al.   GENE THERAPY

GermlineJAK2Mutation in a Family with Hereditary Thrombocytosis

(2012) Adam J. Mead et al.   NEW ENGLAND JOURNAL OF MEDICINE

Vascular smooth muscle Jak2 mediates angiotensin II-induced hypertension via increased levels of reactive oxygen species

(2011) Annet Kirabo et al.   CARDIOVASCULAR RESEARCH

Differential biological activity of disease-associated JAK2 mutants

(2011) Haiying Zou et al.   FEBS LETTERS

The Asn505 mutation of the c-MPL gene, which causes familial essential thrombocythemia, induces autonomous homodimerization of the c-Mpl protein due to strong amino acid polarity

(2009) J. Ding et al.   BLOOD