Article
Biochemistry & Molecular Biology
Liang Zhang, Xian-Fen Wang, Yu-Lu Peng, Yan Zhao, Jian-Ya Qian, Xiangli Ding
Summary: By adding different ionic liquids to HPMC/MSP photophobic film, it was found that the crystallinity, number of holes, and elongation of the film can be increased. Different ionic liquids have varying effects on the physical properties of the film, with some improving ductility while others affecting factors such as water content and glass transition temperature.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Biochemistry & Molecular Biology
Xuepeng Yu, Yueyue Yang, Qing Liu, Zhengyu Jin, Aiquan Jiao
Summary: CEO-loaded chitosan nanoparticles (CNs) were prepared and embedded in HPMC/HPS blends to improve the properties of the formed films. The reinforced nanocomposite films showed enhanced mechanical and barrier properties, as well as sustained release of CEO with antioxidant and antimicrobial effects. These nanocomposite films have great potential for food preservation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Applied
Liang Zhang, Li-Na Yue, Yi-Lin Sui, Yan Zhao, Xiangli Ding, Qian Li, Chen Zhang, Chunsen Wu, Chengcheng Gao, Jian-Ya Qian
Summary: The effects of [EMIM]Ac on HPMC/MSP film include increasing elongation, reducing pore size, increasing pore number, and decreasing Tg value. [EMIM]Ac can improve the ductility and microstructure of the film.
PROGRESS IN ORGANIC COATINGS
(2021)
Article
Materials Science, Multidisciplinary
Xuepeng Yu, Qing Liu, Zhengyu Jin, Aiquan Jiao
Summary: Edible films made from chitosan nanoparticles (CSNPs) can effectively reduce environmental pollution caused by non-degradable plastics. The addition of CSNPs improved the properties of the composite films, including hydrophobicity, thermal stability, mechanical properties, and permeability. The size of the CSNPs played a significant role in determining the performance of the films, with smaller CSNPs showing better enhancement in barrier properties and mechanical properties.
MATERIALS TODAY COMMUNICATIONS
(2023)
Article
Food Science & Technology
Shujuan Jiang, Mengyuan Zhang, Shengnan Jiang, Yanfeng Tuo, Fang Qian, Guangqing Mu
Summary: Whey protein and cellulose derivatives were used to prepare a novel biodegradable composite film, and the mechanical properties of the film were improved by incorporating hydroxypropyl methylcellulose. The addition of transglutaminase further enhanced the mechanical properties of the film.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Food Science & Technology
Liang Zhang, Li-Na Yue, Jian-Ya Qian, Xiang-Li Ding
Summary: This study focuses on the impact of curdlan on the dynamic viscoelastic property, thermal reversible property, viscosity, and fluid types of hydroxypropyl methylcellulose at different temperatures. The results showed that the addition of curdlan increased the storage modulus, loss modulus, gel strength, and viscosity of the blends.
Article
Chemistry, Applied
Shuwei Luo, Lijun Yu, Jiangfeng Song, Caie Wu, Ying Li, Chenchen Zhang
Summary: A lutein-glucosyl stevioside-hydroxypropyl methylcellulose complex prepared using an antisolvent precipitation combined with dynamic high pressure microfluidization method showed improved solubility and stability due to the formation of an amorphous dispersed structure and a high energy state.
Article
Chemistry, Applied
Yanfei Wang, Long Yu, Qingjie Sun, Fengwei Xie
Summary: This study investigated the gelation behavior and phase structure of a mixed system of thermal gel HPMC and cooling gel HPS, revealing different degrees of intermolecular entanglement and phase structure changes. The rheological parameters such as zero-shear viscosity, loss tangent, complex viscosity, and the Arrhenius equation correction coefficient were found to be correlated with the phase structure change, controlled by biopolymer concentration, HPMC/HPS ratio, and temperature. Understanding the relationship between rheological behavior and phase structure provides insights into designing mixed biopolymer systems with desirable properties.
FOOD HYDROCOLLOIDS
(2021)
Article
Chemistry, Physical
Chanoong Lim, Young Hoon Song, Yoojung Song, Jeong Hyun Seo, Dong Soo Hwang, Dong Woog Lee
Summary: HPMC, an FDA-approved water-soluble cellulose derivative, has been used in various wet-adhesion applications for 70 years. Research shows that HPMC adheres strongly to various surfaces in water, with adhesive strength increasing with temperature.
APPLIED SURFACE SCIENCE
(2021)
Article
Chemistry, Applied
Francesco Bigi, Hossein Haghighi, Heinz Wilhelm Siesler, Fabio Licciardello, Andrea Pulvirenti
Summary: In this study, active films based on chitosan/hydroxypropyl methylcellulose blend enriched with sage and nettle leaf extracts were developed for food packaging applications. The films exhibited good mechanical properties, antioxidant activity, and water barrier properties suitable for food packaging.
FOOD HYDROCOLLOIDS
(2021)
Article
Chemistry, Applied
Jingsong Zhu, Zhuojia Qian, Mohamed Eid, Fuchao Zhan, Muhammad Asif Ismail, Jing Li, Bin Li
Summary: This study systematically investigated the stabilizing effect of welan gum on the foam of hydroxypropyl methylcellulose and found that a concentration of 1% with an HPMC/WL ratio of 8:2 resulted in the maximum foaming capacity, while a total concentration of 1% with an HPMC/WL ratio of 2:8 provided the best foam stability. The excellent shear-thinning ability of welan gum and its high apparent viscosity were identified as crucial factors for the outstanding foaming properties of the HPMC/WL composite system.
FOOD HYDROCOLLOIDS
(2021)
Article
Engineering, Environmental
Qilin Guo, Shuang Chen, Zexin Liu, Jicong Yan, Huie Liu
Summary: In this study, a two-step hydrothermal reduction method combined with ice templates was used to prepare graphene/hydroxypropyl methylcellulose composite aerogels. The aerogels exhibited high light absorbance and efficient photo-thermal conversion efficiency, leading to a significant reduction in crude oil viscosity and enhanced adsorption capacity. The aerogels also demonstrated good mechanical properties and reusability.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2022)
Article
Biochemistry & Molecular Biology
Jiayi Zhang, Xianbao Shi, Wei Tao
Summary: The study focuses on the properties of curcumin amorphous solid dispersions (ASDs) formulated with Eudragit EPO (EuD) and hydroxypropyl methylcellulose E50 (HPMC). The results show that HPMC can decrease the particle size of curcumin and inhibit crystallization. Molecular dynamic modeling study reveals that HPMC can convert the arrangement of phospholipid bilayers, leading to enhanced transmembrane performance of curcumin. The Cur-EuD/HPMC 3:1 formulation shows superior oral bioavailability and anti-inflammatory effect. HPMC can be a promising auxiliary excipient for medical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Pharmacology & Pharmacy
L. L. Tundisi, G. B. Mostaco, P. C. Carricondo, D. F. S. Petri
Summary: HPMC, a cellulose ether widely used in drug formulations, is commonly employed in ocular formulations as a viscosity enhancer, gelling agent, and polymeric matrix. Its physicochemical properties facilitate local drug delivery for challenging eye anatomy barriers.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2021)
Article
Thermodynamics
Maria Mucha, Partycja Mroz, Dominika Wrona, Piotr Konca, Joanna Marszalek
Summary: The role of a polymer as a retarder additive is to improve the workability and properties of gypsum paste. This study investigated the influence of water-soluble cellulose derivative HPMC on the setting kinetics, properties, and microstructure of gypsum. The results showed that the presence of HPMC modified the hydration/crystallization process of gypsum, reducing the K value but suggesting a three-dimensional diffusion-controlled mechanism based on the value of n. The mechanical properties of the gypsum plaster composites were correlated with the sample's microstructure.
JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
(2022)
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)