New substituted pyrazole derivatives targeting COXs as potential safe anti-inflammatory agents

Non-acidic 1,3,4-trisubstituted-pyrazole derivatives as lonazolac analogs with promising COX-2 selectivity, anti-inflammatory activity and gastric safety profile

(2018) Khaled R.A. Abdellatif et al.   BIOORGANIC CHEMISTRY

Novel 4-methylsulfonylphenyl derivatives as NSAIDS with preferential COX-2 inhibition

(2018) Noha H Amin et al.   Future Medicinal Chemistry

Synthesis and Pharmacological Activities of Pyrazole Derivatives: A Review

(2018) Khalid Karrouchi et al.   MOLECULES

Nonsteroidal anti-inflammatory drugs and cardiovascular safety – translating pharmacological data into clinical readouts

(2017) Stefania Tacconelli et al.   Expert Opinion On Drug Safety

Design and Synthesis of Novel Pyrazole-Substituted Different Nitrogenous Heterocyclic Ring Systems as Potential Anti-Inflammatory Agents

(2017) Eman Nossier et al.   MOLECULES

Synthesis, cyclooxygenase inhibition and anti-inflammatory evaluation of new 1,3,5-triaryl-4,5-dihydro-1H-pyrazole derivatives possessing methanesulphonyl pharmacophore

(2016) Khaled R. A. Abdellatif et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Synthesis, cyclooxygenase inhibition, anti-inflammatory evaluation and ulcerogenic liability of new 1-phenylpyrazolo[3,4-d]pyrimidine derivatives

(2016) Rania B. Bakr et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Underlying chronic inflammation alters the profile and mechanisms of acute neutrophil recruitment

(2016) Bin Ma et al.   JOURNAL OF PATHOLOGY

Synthesis and biological evaluation of pyrazole chalcones and derived bipyrazoles as anti-inflammatory and antioxidant agents

(2014) Hassan M. Faidallah et al.   ARCHIVES OF PHARMACAL RESEARCH

Synthesis of new 1-(4-methane(amino)sulfonylphenyl)-5-(4-substituted-aminomethylphenyl)-3-trifluoromethyl-1H-pyrazoles: A search for novel nitric oxide donor anti-inflammatory agents

(2014) Khaled R.A. Abdellatif et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Celecoxib analogs bearing benzofuran moiety as cyclooxygenase-2 inhibitors: Design, synthesis and evaluation as potential anti-inflammatory agents

(2014) Ghaneya Sayed Hassan et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of novel 1,3,4-trisubstituted pyrazoles as anti-inflammatory and analgesic agents

(2013) Fatma A. Ragab et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of novel pyrazole and dihydropyrazoles derivatives as potential anti-inflammatory and analgesic agents

(2012) Nagwa M. Abd-El Gawad et al.   ARCHIVES OF PHARMACAL RESEARCH

Celecoxib prodrugs possessing a diazen-1-ium-1,2-diolate nitric oxide donor moiety: Synthesis, biological evaluation and nitric oxide release studies

(2010) Khaled R.A. Abdellatif et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and biological evaluation of a novel series of pyrazole chalcones as anti-inflammatory, antioxidant and antimicrobial agents

(2009) Babasaheb P. Bandgar et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Pro-Inflammatory Enzymes, Cyclooxygenase 1, Cyclooxygenase 2, and 5-Lipooxygenase, Inhibited by Stabilized Rice Bran Extracts

(2009) Bill Roschek et al.   JOURNAL OF MEDICINAL FOOD