Metformin inhibits angiogenesis of endothelial progenitor cells via miR-221-mediated p27 expression and autophagy
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Metformin inhibits angiogenesis of endothelial progenitor cells via miR-221-mediated p27 expression and autophagy
Authors
Keywords
-
Journal
Future Medicinal Chemistry
Volume 11, Issue 17, Pages 2263-2272
Publisher
Future Science Ltd
Online
2019-10-04
DOI
10.4155/fmc-2019-0017
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Metformin reduces TRIB3 expression and restores autophagy flux: an alternative antitumor action
- (2018) Ke Li et al. Autophagy
- Metformin Is Associated with Improved Survival and Decreased Cardiac Events with No Impact on Patency and Limb Salvage after Revascularization for Peripheral Arterial Disease
- (2018) Sikandar Z. Khan et al. ANNALS OF VASCULAR SURGERY
- LncRNA WTAPP1 promotes migration and angiogenesis of endothelial progenitor cells via MMP1 through microRNA 3,120 and Akt/PI3K/autophagy pathways
- (2018) Wen-Dong Li et al. STEM CELLS
- Endothelial Progenitor Cells Biology in Diabetes Mellitus and Peripheral Arterial Disease and their Therapeutic Potential
- (2018) Anna Pyšná et al. Stem Cell Reviews and Reports
- Metformin inhibits endothelial progenitor cell migration by decreasing matrix metalloproteinases, MMP-2 and MMP-9, via the AMPK/mTOR/autophagy pathway
- (2017) Wen-Dong Li et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Multiple therapeutic effect of endothelial progenitor cell regulated by drugs in diabetes and diabetes related disorder
- (2017) Rashmi K. Ambasta et al. Journal of Translational Medicine
- Human aortic smooth muscle cell-derived exosomal miR-221/222 inhibits autophagy via a PTEN/Akt signaling pathway in human umbilical vein endothelial cells
- (2016) Luocheng Li et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Up-regulation of miRNA-221 inhibits hypoxia/reoxygenation-induced autophagy through the DDIT4/mTORC1 and Tp53inp1/p62 pathways
- (2016) Qiying Chen et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Metformin improves circulating endothelial cells and endothelial progenitor cells in type 1 diabetes: MERIT study
- (2016) Fahad W. Ahmed et al. Cardiovascular Diabetology
- Upregulation of miR-483-3p contributes to endothelial progenitor cells dysfunction in deep vein thrombosis patients via SRF
- (2016) Lingshang Kong et al. Journal of Translational Medicine
- Downregulation of let-7e-5p contributes to endothelial progenitor cell dysfunction in deep vein thrombosis via targeting FASLG
- (2016) Lingshang Kong et al. THROMBOSIS RESEARCH
- Endothelial progenitor cells accelerate the resolution of deep vein thrombosis
- (2016) Wen-Dong Li et al. VASCULAR PHARMACOLOGY
- Metformin regulates differentiation of bone marrow-derived endothelial progenitor cells via multiple mechanisms
- (2015) Wen-Dong Li et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Upregulation of MicroRNA-126 Contributes to Endothelial Progenitor Cell Function in Deep Vein Thrombosis via Its Target PIK3R2
- (2015) Qingyou Meng et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Circulating Progenitor Cell Count Predicts Microvascular Outcomes in Type 2 Diabetic Patients
- (2015) Mauro Rigato et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Metformin Causes G1-Phase Arrest via Down-Regulation of MiR-221 and Enhances TRAIL Sensitivity through DR5 Up-Regulation in Pancreatic Cancer Cells
- (2015) Ryoichi Tanaka et al. PLoS One
- Metformin alleviates hepatosteatosis by restoring SIRT1-mediated autophagy induction via an AMP-activated protein kinase-independent pathway
- (2014) Young Mi Song et al. Autophagy
- MicroRNA-221 inhibits autophagy and promotes heart failure by modulating the p27/CDK2/mTOR axis
- (2014) M Su et al. CELL DEATH AND DIFFERENTIATION
- MiR-150 enhances the motility of EPCs in vitro and promotes EPCs homing and thrombus resolving in vivo
- (2014) Wenbin Wang et al. THROMBOSIS RESEARCH
- Autophagy
- (2013) Amber N. Hale et al. Autophagy
- AMP-activated protein kinase: A target for old drugs against diabetes and cancer
- (2013) Gian Luigi Russo et al. BIOCHEMICAL PHARMACOLOGY
- The Concise Guide to PHARMACOLOGY 2013/14: Enzymes
- (2013) Stephen P.H. Alexander et al. BRITISH JOURNAL OF PHARMACOLOGY
- Non-Coding RNAs: Multi-Tasking Molecules in the Cell
- (2013) Anita Gomes et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Does drug therapy reverse endothelial progenitor cell dysfunction in diabetes?
- (2013) Cyrus V. Desouza JOURNAL OF DIABETES AND ITS COMPLICATIONS
- Elevation of miR-221 and -222 in the internal mammary arteries of diabetic subjects and normalization with metformin
- (2013) Chasity B. Coleman et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- AMPK and autophagy get connected
- (2011) D Grahame Hardie EMBO JOURNAL
- Cell-specific effects of miR-221/222 in vessels: Molecular mechanism and therapeutic application
- (2011) Xiaojun Liu et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- A Necessary Role of miR-221 and miR-222 in Vascular Smooth Muscle Cell Proliferation and Neointimal Hyperplasia
- (2009) Xiaojun Liu et al. CIRCULATION RESEARCH
- The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level
- (2008) I Ben Sahra et al. ONCOGENE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More