Emerging lysosomal pathways for quality control at the endoplasmic reticulum

ATL3 gene mutation in a Chinese family with hereditary sensory neuropathy type 1F

(2019) Haiyue Xu et al.   JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM

ATL3 Is a Tubular ER-Phagy Receptor for GABARAP-Mediated Selective Autophagy

(2019) Qingzhou Chen et al.   CURRENT BIOLOGY

ATL3, a cargo receptor for reticulophagy

(2019) Qingzhou Chen et al.   Autophagy

TEX264 Is an Endoplasmic Reticulum-Resident ATG8-Interacting Protein Critical for ER Remodeling during Nutrient Stress

(2019) Heeseon An et al.   MOLECULAR CELL

Intrinsically Disordered Protein TEX264 Mediates ER-phagy

(2019) Haruka Chino et al.   MOLECULAR CELL

Curvature induction and membrane remodeling by FAM134B reticulon homology domain assist selective ER-phagy

(2019) Ramachandra M. Bhaskara et al.   Nature Communications

Cells Deploy a Two-Pronged Strategy to Rectify Misfolded Proinsulin Aggregates

(2019) Corey N. Cunningham et al.   MOLECULAR CELL

A COPII subunit acts with an autophagy receptor to target endoplasmic reticulum for degradation

(2019) Yixian Cui et al.   SCIENCE

CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER Proteostasis

(2018) Matthew D. Smith et al.   DEVELOPMENTAL CELL

Defective collagen proteostasis and matrix formation in the pathogenesis of lysosomal storage disorders

(2018) Carmine Settembre et al.   MATRIX BIOLOGY

Sensory-Neuropathy-Causing Mutations in ATL3 Cause Aberrant ER Membrane Tethering

(2018) Michiel Krols et al.   Cell Reports

ER‐to‐lysosome‐associated degradation of proteasome‐resistant ATZ polymers occurs via receptor‐mediated vesicular transport

(2018) Ilaria Fregno et al.   EMBO JOURNAL

Coordinate regulation of mutant NPC1 degradation by selective ER autophagy and MARCH6-dependent ERAD

(2018) Mark L. Schultz et al.   Nature Communications

A selective ER‐phagy exerts procollagen quality control via a Calnexin‐FAM134B complex

(2018) Alison Forrester et al.   EMBO JOURNAL

Structural and functional analysis of the GABARAP interaction motif (GIM)

(2018) Vladimir V Rogov et al.   EMBO REPORTS

Sensory neuropathy-causing mutations in ATL3 affect ER–mitochondria contact sites and impair axonal mitochondrial distribution

(2018) Michiel Krols et al.   HUMAN MOLECULAR GENETICS

The ER exit sites are specialized ER zones for the transport of cargo proteins from the ER to the Golgi apparatus

(2018) Kazuo Kurokawa et al.   JOURNAL OF BIOCHEMISTRY

Noncanonical autophagy at ER exit sites regulates procollagen turnover

(2018) Shakib Omari et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

mTORC1 hyperactivation arrests bone growth in lysosomal storage disorders by suppressing autophagy

(2017) Rosa Bartolomeo et al.   JOURNAL OF CLINICAL INVESTIGATION

Full length RTN3 regulates turnover of tubular endoplasmic reticulum via selective autophagy

(2017) Paolo Grumati et al.   eLife

Protein aggregation and ER stress

(2016) Navit Ogen-Shtern et al.   BRAIN RESEARCH

Protein sorting at the ER–Golgi interface

(2016) Natalia Gomez-Navarro et al.   JOURNAL OF CELL BIOLOGY

FAM134B, the Selective Autophagy Receptor for Endoplasmic Reticulum Turnover, Inhibits Replication of Ebola Virus Strains Makona and Mayinga

(2016) Abhilash I. Chiramel et al.   JOURNAL OF INFECTIOUS DISEASES

Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery

(2016) Fiorenza Fumagalli et al.   NATURE CELL BIOLOGY

Increased spatiotemporal resolution reveals highly dynamic dense tubular matrices in the peripheral ER

(2016) J. Nixon-Abell et al.   SCIENCE

N-Glycan-based ER Molecular Chaperone and Protein Quality Control System: The Calnexin Binding Cycle

(2016) Lydia Lamriben et al.   TRAFFIC

The Pathway of Collagen Secretion

(2015) Vivek Malhotra et al.   Annual Review of Cell and Developmental Biology

The endoplasmic reticulum: structure, function and response to cellular signaling

(2015) Dianne S. Schwarz et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Role for Lipid Droplet Biogenesis and Microlipophagy in Adaptation to Lipid Imbalance in Yeast

(2015) Jason D. Vevea et al.   DEVELOPMENTAL CELL

FGF signalling regulates bone growth through autophagy

(2015) Laura Cinque et al.   NATURE

Regulation of endoplasmic reticulum turnover by selective autophagy

(2015) Aliaksandr Khaminets et al.   NATURE

Receptor-mediated selective autophagy degrades the endoplasmic reticulum and the nucleus

(2015) Keisuke Mochida et al.   NATURE

A novel missense mutation confirms ATL3 as a gene for hereditary sensory neuropathy type 1

(2014) Dirk Fischer et al.   BRAIN

Sensory neuropathy with bone destruction due to a mutation in the membrane-shaping atlastin GTPase 3

(2014) Uwe Kornak et al.   BRAIN

ER-associated degradation: Protein quality control and beyond

(2014) Annamaria Ruggiano et al.   JOURNAL OF CELL BIOLOGY

ER-phagy mediates selective degradation of endoplasmic reticulum independently of the core autophagy machinery

(2014) S. Schuck et al.   JOURNAL OF CELL SCIENCE

Quality Control Autophagy Degrades Soluble ERAD-Resistant Conformers of the Misfolded Membrane Protein GnRHR

(2014) Scott A. Houck et al.   MOLECULAR CELL

Cargo recognition and trafficking in selective autophagy

(2014) Alexandra Stolz et al.   NATURE CELL BIOLOGY

A model for the generation and interconversion of ER morphologies

(2014) Tom Shemesh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Plasma cells require autophagy for sustainable immunoglobulin production

(2013) Niccolò Pengo et al.   NATURE IMMUNOLOGY

Signals from the lysosome: a control centre for cellular clearance and energy metabolism

(2013) Carmine Settembre et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Protein Folding in the Endoplasmic Reticulum

(2013) I. Braakman et al.   Cold Spring Harbor Perspectives in Biology

Endoplasmic Reticulum Structure and Interconnections with Other Organelles

(2013) A. R. English et al.   Cold Spring Harbor Perspectives in Biology

Microautophagy: lesser-known self-eating

(2011) Wen-wen Li et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Microautophagy of Cytosolic Proteins by Late Endosomes

(2011) Ranjit Sahu et al.   DEVELOPMENTAL CELL

Autophagy Regulates Endoplasmic Reticulum Homeostasis and Calcium Mobilization in T Lymphocytes

(2010) W. Jia et al.   JOURNAL OF IMMUNOLOGY

Niemann-Pick disease type C

(2010) Marie T Vanier   Orphanet Journal of Rare Diseases

Mutant INS-Gene Induced Diabetes of Youth: Proinsulin Cysteine Residues Impose Dominant-Negative Inhibition on Wild-Type Proinsulin Transport

(2010) Ming Liu et al.   PLoS One

An Autophagy-Enhancing Drug Promotes Degradation of Mutant  1-Antitrypsin Z and Reduces Hepatic Fibrosis

(2010) T. Hidvegi et al.   SCIENCE

Proinsulin misfolding and diabetes: mutant INS gene-induced diabetes of youth

(2010) Ming Liu et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Autophagy eliminates a specific species of misfolded procollagen and plays a protective role in cell survival against ER stress

(2009) Yoshihito Ishida et al.   Autophagy

Piecemeal microautophagy of the nucleus: Genetic and morphological traits

(2009) Roswitha Krick et al.   Autophagy

A Class of Dynamin-like GTPases Involved in the Generation of the Tubular ER Network

(2009) Junjie Hu et al.   CELL

Endoplasmic Reticulum-associated Degradation (ERAD) and Autophagy Cooperate to Degrade Polymerogenic Mutant Serpins

(2009) Heike Kroeger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagic Elimination of Misfolded Procollagen Aggregates in the Endoplasmic Reticulum as a Means of Cell Protection

(2009) Yoshihito Ishida et al.   MOLECULAR BIOLOGY OF THE CELL

Mutations in FAM134B, encoding a newly identified Golgi protein, cause severe sensory and autonomic neuropathy

(2009) Ingo Kurth et al.   NATURE GENETICS

The evolutionary consequences of erroneous protein synthesis

(2009) D. Allan Drummond et al.   NATURE REVIEWS GENETICS

Genetic diseases of connective tissues: cellular and extracellular effects of ECM mutations

(2009) John F. Bateman et al.   NATURE REVIEWS GENETICS

Autophagy: Principles and significance in health and disease

(2008) Virginia Todde et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Piecemeal Microautophagy of the Nucleus Requires the Core Macroautophagy Genes

(2008) R. Krick et al.   MOLECULAR BIOLOGY OF THE CELL