Zinc(II) Complexes of Acylpyrazolones Decorated with a Cyclohexyl Group Display Antiproliferative Activity Against Human Breast Cancer Cells

Synthesis, characterization and cytotoxicity of arene–ruthenium(ii) complexes with acylpyrazolones functionalized with aromatic groups in the acyl moiety

(2018) Fabio Marchetti et al.   DALTON TRANSACTIONS

Crystal structures and anticancer activities of five novel pyrazolone-enamine transition metal complexes with 4-benzoyl-3-methyl-1-phenyl-2-pyrazolin-5-one

(2018) Ziao Zong et al.   JOURNAL OF MOLECULAR STRUCTURE

Platinum, palladium, gold and ruthenium complexes as anticancer agents: Current clinical uses, cytotoxicity studies and future perspectives

(2017) Tatjana Lazarević et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A detailed study on the interaction of a novel water-soluble glycine bridged zinc(II) Schiff base coordination polymer with BSA: Synthesis, crystal structure, molecular docking and cytotoxicity effect against A549, Jurkat and Raji cell lines

(2017) Zahra Asadi et al.   INORGANICA CHIMICA ACTA

Biologically Active Cu(II), Co(II), Ni(II) and Zn(II) Complexes of Pyrimidine Derivative Schiff Base: DNA Binding, Antioxidant, Antibacterial and In Vitro Anticancer Studies

(2017) Nagaraj Revathi et al.   JOURNAL OF FLUORESCENCE

New anticancer zinc(II) complexes comprising thiosemicarbazones of saturated ring: structure, DNA/protein binding, DNA cleavage, topoisomerase-1 inhibition and anti-proliferation studies

(2016) Vikneswaran Rajamuthy et al.   APPLIED ORGANOMETALLIC CHEMISTRY

Neuronal membrane bioreactor as a tool for testing crocin neuroprotective effect in Alzheimer’s disease

(2016) Sabrina Morelli et al.   CHEMICAL ENGINEERING JOURNAL

Synthesis, Structure, and Anticancer Activity of Arene–Ruthenium(II) Complexes with Acylpyrazolones Bearing Aliphatic Groups in the Acyl Moiety

(2016) Jessica Palmucci et al.   INORGANIC CHEMISTRY

Current and future potential of metallo drugs: Revisiting DNA-binding of metal containing molecules and their diverse mechanism of action

(2016) Mehvash Zaki et al.   INORGANICA CHIMICA ACTA

Biological evaluation of dimethylpyridine–platinum complexes with potent antiproliferative activity

(2016) Robert Czarnomysy et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Cytotoxic and apoptogenic effect of hypericin, the bioactive component of Hypericum perforatum on the MCF-7 human breast cancer cell line

(2015) Seyed Abbas Mirmalek et al.   Cancer Cell International

Synthesis, characterization and biological evaluation of Rutin–zinc(II) flavonoid -metal complex

(2015) Norma Estefania Andrades Ikeda et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Recent advances in acylpyrazolone metal complexes and their potential applications

(2015) Fabio Marchetti et al.   COORDINATION CHEMISTRY REVIEWS

Zn(ii) and Cu(ii) complexes containing bioactive O,O-chelated ligands: homoleptic and heteroleptic metal-based biomolecules

(2015) Barbara Sanz Mendiguchia et al.   DALTON TRANSACTIONS

Zn(II)-curc targets p53 in thyroid cancer cells

(2015) ALESSIA GARUFI et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Osteogenic and osteoclastogenic differentiation of co-cultured cells in polylactic acid–nanohydroxyapatite fiber scaffolds

(2015) Sabrina Morelli et al.   JOURNAL OF BIOTECHNOLOGY

Dinuclear (η6-arene) ruthenium(II) acylpyrazolone complexes: Synthesis, characterization and cytotoxicity

(2015) Riccardo Pettinari et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Cytotoxicity, DNA binding and cell apoptosis induction of a zinc(ii) complex of HBrQ

(2015) Hai-Rong Zhang et al.   MedChemComm

Arene–Ruthenium(II) Acylpyrazolonato Complexes: Apoptosis-Promoting Effects on Human Cancer Cells

(2014) Riccardo Pettinari et al.   JOURNAL OF MEDICINAL CHEMISTRY

Degradation of mutant p53H175 protein by Zn(II) through autophagy

(2014) A Garufi et al.   Cell Death & Disease

Photodynamic Agents with Anti-metastatic Activities

(2013) Balayeshwanth R. Vummidi et al.   ACS Chemical Biology

Non-classical anticancer agents: on the way to water soluble zinc(ii) heteroleptic complexes

(2013) Barbara Sanz Mendiguchia et al.   DALTON TRANSACTIONS

Improving the bioactivity of Zn(ii)-curcumin based complexes

(2013) Daniela Pucci et al.   DALTON TRANSACTIONS

Synthesis and characterization of some water soluble Zn(ii) complexes with (E)-N-(pyridin-2-ylmethylene)arylamines that regulate tumour cell death by interacting with DNA

(2013) Tushar S. Basu Baul et al.   DALTON TRANSACTIONS

A fluorescent curcumin-based Zn(II)-complex reactivates mutant (R175H and R273H) p53 in cancer cells

(2013) Alessia Garufi et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Zn(II) coordination compounds derived from 4-acyl pyrazolones and 1,10 phenanthroline: Syntheses, crystal structures, spectral analysis and DNA binding studies

(2013) R.N. Jadeja et al.   POLYHEDRON

Zinc protects HepG2 cells against the oxidative damage and DNA damage induced by ochratoxin A

(2013) Juanjuan Zheng et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Synthesis and characterization of copper(II) and zinc(II)-based potential chemotherapeutic compounds: Their biological evaluation viz. DNA binding profile, cleavage and antimicrobial activity

(2012) Sartaj Tabassum et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A Series of Oxyimine-Based Macrocyclic Dinuclear Zinc(II) Complexes Enhances Phosphate Ester Hydrolysis, DNA Binding, DNA Hydrolysis, and Lactate Dehydrogenase Inhibition and Induces Apoptosis

(2012) Sellamuthu Anbu et al.   INORGANIC CHEMISTRY

Neuronal growth and differentiation on biodegradable membranes

(2012) Sabrina Morelli et al.   Journal of Tissue Engineering and Regenerative Medicine

DNA binding and cytotoxicity of fluorescent curcumin-based Zn(ii) complexes

(2012) Daniela Pucci et al.   MedChemComm

“Green light” for Zn(ii) mesogens

(2012) Daniela Pucci et al.   RSC Advances

Non-classical anticancer agents: synthesis and biological evaluation of zinc(ii) heteroleptic complexes

(2010) Paola F. Liguori et al.   DALTON TRANSACTIONS

Comparative Solution Equilibrium Study of the Interactions of Copper(II), Iron(II) and Zinc(II) with Triapine (3-Aminopyridine-2-carbaldehyde Thiosemicarbazone) and Related Ligands

(2010) Éva A. Enyedy et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Zinc(II) complexes of 2-acetyl pyridine 1-(4-fluorophenyl)-piperazinyl thiosemicarbazone: Synthesis, spectroscopic study and crystal structures – Potential anticancer drugs

(2010) Tatjana P. Stanojkovic et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Synthesis, structural and spectroscopic characterization and biomimetic properties of new copper, manganese, zinc complexes: Identification of possible superoxide-dismutase mimics bearing hydroxyl radical generating/scavenging abilities

(2010) Giulio Lupidi et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Design and synthesis of nonpeptidic, small molecule inhibitors for the Mycobacterium tuberculosis protein tyrosine phosphatase PtpB

(2010) Katherine A. Rawls et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Inhibitory effect of β-diketones and their metal complexes on TNF-α induced expression of ICAM-1 on human endothelial cells

(2009) Francesco Caruso et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Self-assembled synthesis, characterization and antimicrobial activity of zinc(II) salicylaldimine complexes

(2009) Małgorzata T. Kaczmarek et al.   INORGANICA CHIMICA ACTA

Current state for the development of metallopharmaceutics and anti-diabetic metal complexes

(2008) Hiromu Sakurai et al.   CHEMICAL SOCIETY REVIEWS

Molecular mechanism of antidiabetic zinc–allixin complexes: regulations of glucose utilization and lipid metabolism

(2008) Akihiro Nakayama et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY