STK 38 kinase acts as XPO 1 gatekeeper regulating the nuclear export of autophagy proteins and other cargoes

Publisher Correction: Localization of RalB signaling at endomembrane compartments and its modulation by autophagy

(2019) Manish Kumar Singh et al.   Scientific Reports

Nuclear Export Inhibition Enhances HLH-30/TFEB Activity, Autophagy, and Lifespan

(2018) Melissa J. Silvestrini et al.   Cell Reports

Quantitative Analysis Reveals that Actin and Src-Family Kinases Regulate Nuclear YAP1 and Its Export

(2018) Nil Ege et al.   Cell Systems

The ubiquitin ligase Cullin5SOCS2 regulates NDR1/STK38 stability and NF-κB transactivation

(2017) Indranil Paul et al.   Scientific Reports

The Second-Generation Exportin-1 Inhibitor KPT-8602 Demonstrates Potent Activity against Acute Lymphoblastic Leukemia

(2016) Thomas Vercruysse et al.   CLINICAL CANCER RESEARCH

YAP Nuclear Localization in the Absence of Cell-Cell Contact Is Mediated by a Filamentous Actin-dependent, Myosin II- and Phospho-YAP-independent Pathway during Extracellular Matrix Mechanosensing

(2016) Arupratan Das et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Autophagic Flux Probe that Releases an Internal Control

(2016) Takeshi Kaizuka et al.   MOLECULAR CELL

Proteogenomics connects somatic mutations to signalling in breast cancer

(2016) Philipp Mertins et al.   NATURE

Spatially resolved proteomic mapping in living cells with the engineered peroxidase APEX2

(2016) Victoria Hung et al.   Nature Protocols

Sensitivity of mass spectrometry analysis depends on the shape of the filtration unit used for filter aided sample preparation (FASP)

(2016) Joanna Lipecka et al.   PROTEOMICS

CRISPaint allows modular base-specific gene tagging using a ligase-4-dependent mechanism

(2016) Jonathan L. Schmid-Burgk et al.   Nature Communications

Mitochondrial clearance by the STK38 kinase supports oncogenic Ras-induced cell transformation

(2016) Audrey Bettoun et al.   Oncotarget

The Roles of NDR Protein Kinases in Hippo Signalling

(2016) Alexander Hergovich   Genes

Identifying Drug-Target Selectivity of Small-Molecule CRM1/XPO1 Inhibitors by CRISPR/Cas9 Genome Editing

(2015) Jasper E. Neggers et al.   CHEMISTRY & BIOLOGY

NDR Functions as a Physiological YAP1 Kinase in the Intestinal Epithelium

(2015) Lei Zhang et al.   CURRENT BIOLOGY

The Pro-apoptotic STK38 Kinase Is a New Beclin1 Partner Positively Regulating Autophagy

(2015) Carine Joffre et al.   CURRENT BIOLOGY

Analysis of the Histone H3.1 Interactome: A Suitable Chaperone for the Right Event

(2015) Eric I. Campos et al.   MOLECULAR CELL

Matrix stiffness drives epithelial–mesenchymal transition and tumour metastasis through a TWIST1–G3BP2 mechanotransduction pathway

(2015) Spencer C. Wei et al.   NATURE CELL BIOLOGY

2016 update of the PRIDE database and its related tools

(2015) Juan Antonio Vizcaíno et al.   NUCLEIC ACIDS RESEARCH

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning

(2015) Koray Kırlı et al.   eLife

Constitutively active NDR1-PIF kinase functions independent of MST1 and hMOB1 signalling

(2014) Dorthe Cook et al.   CELLULAR SIGNALLING

Selective inhibitors of nuclear export (SINE)– a novel class of anti-cancer agents

(2014) Kaushal Parikh et al.   Journal of Hematology & Oncology

Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover

(2014) David J. Elzi et al.   JOURNAL OF PROTEOME RESEARCH

Ischemia in Tumors Induces Early and Sustained Phosphorylation Changes in Stress Kinase Pathways but Does Not Affect Global Protein Levels

(2014) Philipp Mertins et al.   MOLECULAR & CELLULAR PROTEOMICS

Ultradeep Human Phosphoproteome Reveals a Distinct Regulatory Nature of Tyr and Ser/Thr-Based Signaling

(2014) Kirti Sharma et al.   Cell Reports

Phosphorylation of human chromosome maintenance 1 mediates association with 14-3-3 proteins

(2013) Sang Sun Kang et al.   Animal Cells and Systems

Quantitative Study of the Interactome of PKCζ Involved in the EGF-induced Tumor Cell Chemotaxis

(2013) Ruibing Chen et al.   JOURNAL OF PROTEOME RESEARCH

Proteomic Mapping of Mitochondria in Living Cells via Spatially Restricted Enzymatic Tagging

(2013) H.-W. Rhee et al.   SCIENCE

Structure of a Truncation Mutant of the Nuclear Export Factor CRM1 Provides Insights into the Auto-Inhibitory Role of Its C-Terminal Helix

(2013) Cyril Dian et al.   STRUCTURE

Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemia

(2012) R. Lapalombella et al.   BLOOD

The Cellular EJC Interactome Reveals Higher-Order mRNP Structure and an EJC-SR Protein Nexus

(2012) Guramrit Singh et al.   CELL

NDR1/STK38 potentiates NF-κB activation by its kinase activity

(2012) Dan-Dan Shi et al.   CELL BIOCHEMISTRY AND FUNCTION

Downstream of human NDR kinases: Impacting on c-myc and p21 protein stability to control cell cycle progression

(2011) Hauke Cornils et al.   CELL CYCLE

Human NDR Kinases Control G1/S Cell Cycle Transition by Directly Regulating p21 Stability

(2011) H. Cornils et al.   MOLECULAR AND CELLULAR BIOLOGY

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia

(2011) Xose S. Puente et al.   NATURE

The MST1 and hMOB1 Tumor Suppressors Control Human Centrosome Duplication by Regulating NDR Kinase Phosphorylation

(2009) Alexander Hergovich et al.   CURRENT BIOLOGY

Hippo signaling regulates Yorkie nuclear localization and activity through 14-3-3 dependent and independent mechanisms

(2009) Fangfang Ren et al.   DEVELOPMENTAL BIOLOGY

Universal sample preparation method for proteome analysis

(2009) Jacek R Wiśniewski et al.   NATURE METHODS

NDR Kinase Is Activated by RASSF1A/MST1 in Response to Fas Receptor Stimulation and Promotes Apoptosis

(2008) Anton Vichalkovski et al.   CURRENT BIOLOGY

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY