Genetic inactivation of the LIGHT (TNFSF14) cytokine in mice restores glucose homeostasis and diminishes hepatic steatosis

Changes in CDKN2A/2B expression associate with T-cell phenotype modulation in atherosclerosis and type 2 diabetes mellitus

(2018) Ángela VinuÉ et al.   Translational Research

Long noncoding RNA licensing of obesity-linked hepatic lipogenesis and NAFLD pathogenesis

(2018) Xu-Yun Zhao et al.   Nature Communications

Adipose tissue macrophages induce hepatic neutrophil recruitment and macrophage accumulation in mice

(2017) Mitchell Bijnen et al.   GUT

Transmembrane BAX Inhibitor motif-containing 1, a novel anti-inflammatory approach for nonalcoholic steatohepatitis treatment

(2017) Alexander Wree et al.   HEPATOLOGY

Shining LIGHT on the metabolic role of the cytokine TNFSF14 and the implications on hepatic IL-6 production

(2017) Bernadette M Saunders et al.   IMMUNOLOGY AND CELL BIOLOGY

LIGHT/TNFSF14 is increased in patients with type 2 diabetes mellitus and promotes islet cell dysfunction and endothelial cell inflammation in vitro

(2016) Bente Halvorsen et al.   DIABETOLOGIA

A diet-induced animal model of non-alcoholic fatty liver disease and hepatocellular cancer

(2016) Amon Asgharpour et al.   JOURNAL OF HEPATOLOGY

The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD)

(2016) Elena Buzzetti et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Hepatic lipase inactivation decreases atherosclerosis in insulin resistance by reducing LIGHT/Lymphotoxin β-Receptor pathway

(2016) Andrea Herrero-Cervera et al.   THROMBOSIS AND HAEMOSTASIS

Ink4/Arf locus restores glucose tolerance and insulin sensitivity by reducing hepatic steatosis and inflammation in mice with impaired IRS2-dependent signalling

(2015) Ángela Vinué et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Hepatic lipase deficiency produces glucose intolerance, inflammation and hepatic steatosis

(2015) Irene Andrés-Blasco et al.   JOURNAL OF ENDOCRINOLOGY

Increased Serum Levels of LIGHT/TNFSF14 in Nonalcoholic Fatty Liver Disease: Possible Role in Hepatic Inflammation

(2015) Kari Otterdal et al.   Clinical and Translational Gastroenterology

Metabolic Activation of Intrahepatic CD8+ T Cells and NKT Cells Causes Nonalcoholic Steatohepatitis and Liver Cancer via Cross-Talk with Hepatocytes

(2014) Monika Julia Wolf et al.   CANCER CELL

Cellular and molecular players in adipose tissue inflammation in the development of obesity-induced insulin resistance

(2013) Byung-Cheol Lee et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Innate Immune Receptors: Key Regulators of Metabolic Disease Progression

(2013) Chengcheng Jin et al.   Cell Metabolism

OMIP-017: Human CD4+helper T-cell subsets including follicular helper cells

(2013) Yolanda D. Mahnke et al.   CYTOMETRY PART A

Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis

(2013) Quentin M. Anstee et al.   Nature Reviews Gastroenterology & Hepatology

LIGHT/TNFSR14 Can Regulate Hepatic Lipase Expression by Hepatocytes Independent of T Cells and Kupffer Cells

(2013) Bijoy Chellan et al.   PLoS One

Increased dosage ofInk4/Arfprotects against glucose intolerance and insulin resistance associated with aging

(2012) Herminia González-Navarro et al.   AGING CELL

Decoy receptor 3: A pleiotropic immunomodulator and biomarker for inflammatory diseases, autoimmune diseases and cancer

(2011) Wan-Wan Lin et al.   BIOCHEMICAL PHARMACOLOGY

LIGHT/TNFSF14 enhances adipose tissue inflammatory responses through its interaction with HVEM

(2011) Hong-Min Kim et al.   FEBS LETTERS

The tumor necrosis factor family member LIGHT is a target for asthmatic airway remodeling

(2011) Taylor A Doherty et al.   NATURE MEDICINE

Human Fatty Liver Disease: Old Questions and New Insights

(2011) J. C. Cohen et al.   SCIENCE

Adipose Tissue Dysfunction Signals Progression of Hepatic Steatosis Towards Nonalcoholic Steatohepatitis in C57Bl/6 Mice

(2010) C. Duval et al.   DIABETES

LIGHT (TNFSF14) inhibits adipose differentiation without affecting adipocyte metabolism

(2010) G Tiller et al.   INTERNATIONAL JOURNAL OF OBESITY

Association between dietary nutrient composition and the incidence of cirrhosis or liver cancer in the united states population

(2009) George N. Ioannou et al.   HEPATOLOGY

Molecular Mechanisms of Atherosclerosis in Metabolic Syndrome

(2008) Herminia González-Navarro et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The Kruppel-Like Factor 6 Genotype Is Associated With Fibrosis in Nonalcoholic Fatty Liver Disease

(2008) Luca Miele et al.   GASTROENTEROLOGY

Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis

(2008) Kristiaan Wouters et al.   HEPATOLOGY

Nutritional investigation of non-obese patients with non-alcoholic fatty liver disease: The significance of dietary cholesterol

(2008) Kenichiro Yasutake et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY