Enhanced generation of intraluminal vesicles in neuronal late endosomes in the brain of a Down syndrome mouse model with endosomal dysfunction

Dysfunction of autophagy and endosomal-lysosomal pathways: Roles in pathogenesis of Down syndrome and Alzheimer's Disease

(2018) Daniel J. Colacurcio et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cystatin C prevents neuronal loss and behavioral deficits via the endosomal pathway in a mouse model of down syndrome

(2018) Gurjinder Kaur et al.   NEUROBIOLOGY OF DISEASE

Apolipoprotein E4 genotype compromises brain exosome production

(2018) Katherine Y Peng et al.   BRAIN

Enhanced exosome secretion in Down syndrome brain - a protective mechanism to alleviate neuronal endosomal abnormalities

(2017) Sébastien A. Gauthier et al.   Acta Neuropathologica Communications

Partial BACE1 reduction in a Down syndrome mouse model blocks Alzheimer-related endosomal anomalies and cholinergic neurodegeneration: role of APP-CTF

(2016) Ying Jiang et al.   NEUROBIOLOGY OF AGING

Evidence that the rab5 effector APPL1 mediates APP-βCTF-induced dysfunction of endosomes in Down syndrome and Alzheimer’s disease

(2015) S Kim et al.   MOLECULAR PSYCHIATRY

Glutamatergic Transmission Aberration: A Major Cause of Behavioral Deficits in a Murine Model of Down's Syndrome

(2014) G. Kaur et al.   JOURNAL OF NEUROSCIENCE

Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles

(2013) Marina Colombo et al.   JOURNAL OF CELL SCIENCE

Hrs- and CD63-Dependent Competing Mechanisms Make Different Sized Endosomal Intraluminal Vesicles

(2013) James R. Edgar et al.   TRAFFIC

ALIX and the multivesicular endosome: ALIX in Wonderland

(2013) Christin Bissig et al.   TRENDS IN CELL BIOLOGY

The Exosome Secretory Pathway Transports Amyloid Precursor Protein Carboxyl-terminal Fragments from the Cell into the Brain Extracellular Space

(2012) Rocio Perez-Gonzalez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Syndecan–syntenin–ALIX regulates the biogenesis of exosomes

(2012) Maria Francesca Baietti et al.   NATURE CELL BIOLOGY

Multivesicular bodies in neurons: Distribution, protein content, and trafficking functions

(2011) Christopher S. Von Bartheld et al.   PROGRESS IN NEUROBIOLOGY

Updated national birth prevalence estimates for selected birth defects in the United States, 2004-2006

(2010) Samantha E. Parker et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A–C

(2010) Chieh Hsu et al.   JOURNAL OF CELL BIOLOGY

Down Syndrome Fibroblast Model of Alzheimer-Related Endosome Pathology

(2008) Anne M. Cataldo et al.   AMERICAN JOURNAL OF PATHOLOGY

Systemic pathology in aged mouse models of Down's syndrome and Alzheimer's disease

(2008) Seymour Levine et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Trafficking and function of the tetraspanin CD63

(2008) Maaike S. Pols et al.   EXPERIMENTAL CELL RESEARCH

Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes

(2008) K. Trajkovic et al.   SCIENCE

The ESCRT-I Subunit TSG101 Controls Endosome-to-Cytosol Release of Viral RNA

(2008) Pierre-Philippe Luyet et al.   TRAFFIC