Planar cell polarity signaling regulates polarized second heart field morphogenesis to promote both arterial and venous pole septation

Epithelial Properties of the Second Heart Field

(2018) Claudio Cortes et al.   CIRCULATION RESEARCH

From instruction to output: Wnt/PCP signaling in development and cancer

(2018) Ashley Ceinwen Humphries et al.   CURRENT OPINION IN CELL BIOLOGY

Planar Cell Polarity Signaling in Mammalian Cardiac Morphogenesis

(2018) Ding Li et al.   PEDIATRIC CARDIOLOGY

Synchronized mesenchymal cell polarization and differentiation shape the formation of the murine trachea and esophagus

(2018) Keishi Kishimoto et al.   Nature Communications

Coming to Consensus: A Unifying Model Emerges for Convergent Extension

(2018) Robert J. Huebner et al.   DEVELOPMENTAL CELL

Evolutionarily conservedTbx5–Wnt2/2bpathway orchestrates cardiopulmonary development

(2018) Jeffrey D. Steimle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Planar cell polarity in development and disease

(2017) Mitchell T. Butler et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Epithelial tension in the second heart field promotes mouse heart tube elongation

(2017) Alexandre Francou et al.   Nature Communications

Temporally Distinct Six2 -Positive Second Heart Field Progenitors Regulate Mammalian Heart Development and Disease

(2017) Zhengfang Zhou et al.   Cell Reports

Spatial regulation of cell cohesion by Wnt5a during second heart field progenitor deployment

(2016) Ding Li et al.   DEVELOPMENTAL BIOLOGY

Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD

(2016) Hoeke A. Baarsma et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tissue morphodynamics: Translating planar polarity cues into polarized cell behaviors

(2016) Danelle Devenport   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Alternative Wnt Signaling Activates YAP/TAZ

(2015) Hyun Woo Park et al.   CELL

Wnt5a and Wnt11 inhibit the canonical Wnt pathway and promote cardiac progenitor development via the Caspase-dependent degradation of AKT

(2015) Joseph A. Bisson et al.   DEVELOPMENTAL BIOLOGY

Mapping the dynamic expression of Wnt11 and the lineage contribution of Wnt11-expressing cells during early mouse development

(2015) Tanvi Sinha et al.   DEVELOPMENTAL BIOLOGY

The Formin DAAM Functions as Molecular Effector of the Planar Cell Polarity Pathway during Axonal Development in Drosophila

(2015) R. Gombos et al.   JOURNAL OF NEUROSCIENCE

N-cadherin prevents the premature differentiation of anterior heart field progenitors in the pharyngeal mesodermal microenvironment

(2014) Boon-Seng Soh et al.   CELL RESEARCH

Tbx1 Coordinates Addition of Posterior Second Heart Field Progenitor Cells to the Arterial and Venous Poles of the Heart

(2014) M. Sameer Rana et al.   CIRCULATION RESEARCH

TBX1 regulates epithelial polarity and dynamic basal filopodia in the second heart field

(2014) A. Francou et al.   DEVELOPMENT

Loss of Wnt5a disrupts second heart field cell deployment and may contribute to OFT malformations in DiGeorge syndrome

(2014) Tanvi Sinha et al.   HUMAN MOLECULAR GENETICS

Appropriate Crypt Formation in the Uterus for Embryo Homing and Implantation Requires Wnt5a-ROR Signaling

(2014) Jeeyeon Cha et al.   Cell Reports

Vangl2-Regulated Polarisation of Second Heart Field-Derived Cells Is Required for Outflow Tract Lengthening during Cardiac Development

(2014) Simon A. Ramsbottom et al.   PLoS Genetics

Expression of the BMP Receptor Alk3 in the Second Heart Field Is Essential for Development of the Dorsal Mesenchymal Protrusion and Atrioventricular Septation

(2013) Laura E. Briggs et al.   CIRCULATION RESEARCH

The Formin Daam1 and Fascin Directly Collaborate to Promote Filopodia Formation

(2013) Richa Jaiswal et al.   CURRENT BIOLOGY

An autocrine Wnt5a-Ror signaling loop mediates sympathetic target innervation

(2013) Yun Kyoung Ryu et al.   DEVELOPMENTAL BIOLOGY

Coordination of heart and lung co-development by a multipotent cardiopulmonary progenitor

(2013) Tien Peng et al.   NATURE

Normal and abnormal development of the intrapericardial arterial trunks in humans and mice

(2012) Robert H. Anderson et al.   CARDIOVASCULAR RESEARCH

Planar Cell Polarity Links Axes of Spatial Dynamics in Neural-Tube Closure

(2012) Tamako Nishimura et al.   CELL

Lineage Tree for the Venous Pole of the Heart

(2012) Fabienne Lescroart et al.   CIRCULATION RESEARCH

Wnt5a and Wnt11 are essential for second heart field progenitor development

(2012) E. D. Cohen et al.   DEVELOPMENT

Disheveled mediated planar cell polarity signaling is required in the second heart field lineage for outflow tract morphogenesis

(2012) Tanvi Sinha et al.   DEVELOPMENTAL BIOLOGY

Tbx5-Hedgehog Molecular Networks Are Essential in the Second Heart Field for Atrial Septation

(2012) Linglin Xie et al.   DEVELOPMENTAL CELL

The pathogenesis of atrial and atrioventricular septal defects with special emphasis on the role of the dorsal mesenchymal protrusion

(2012) Laura E. Briggs et al.   DIFFERENTIATION

Transcriptional Control in Cardiac Progenitors: Tbx1 Interacts with the BAF Chromatin Remodeling Complex and Regulates Wnt5a

(2012) Li Chen et al.   PLoS Genetics

Epigenetics and Cardiovascular Development

(2011) Ching-Pin Chang et al.   Annual Review of Physiology

Principles of planar polarity in animal development

(2011) L. V. Goodrich et al.   DEVELOPMENT

Hox genes define distinct progenitor sub-domains within the second heart field

(2011) Nicolas Bertrand et al.   DEVELOPMENTAL BIOLOGY

Pointing in the right direction: new developments in the field of planar cell polarity

(2011) Roy Bayly et al.   NATURE REVIEWS GENETICS

Myocardial Lineage Development

(2010) Sylvia M. Evans et al.   CIRCULATION RESEARCH

WNT5A/JNK and FGF/MAPK Pathways Regulate the Cellular Events Shaping the Vertebrate Limb Bud

(2010) Jerome Gros et al.   CURRENT BIOLOGY

Dishevelled-associated activator of morphogenesis 1 (Daam1) is required for heart morphogenesis

(2010) D. Li et al.   DEVELOPMENT

Disruption of PCP signaling causes limb morphogenesis and skeletal defects and may underlie Robinow syndrome and brachydactyly type B

(2010) Bing Wang et al.   HUMAN MOLECULAR GENETICS

The Role of Spatially Controlled Cell Proliferation in Limb Bud Morphogenesis

(2010) Bernd Boehm et al.   PLOS BIOLOGY

sonic hedgehog is required in pulmonary endoderm for atrial septation

(2009) A. D. Hoffmann et al.   DEVELOPMENT

WNT5Amutations in patients with autosomal dominant Robinow syndrome

(2009) Anthony D. Person et al.   DEVELOPMENTAL DYNAMICS

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

A Caudal Proliferating Growth Center Contributes to Both Poles of the Forming Heart Tube

(2008) Gert van den Berg et al.   CIRCULATION RESEARCH

Intracardiac septation requires hedgehog-dependent cellular contributions from outside the heart

(2008) M. M. Goddeeris et al.   DEVELOPMENT

The developmental genetics of congenital heart disease

(2008) Benoit G. Bruneau   NATURE

Murine Dishevelled 3 Functions in Redundant Pathways with Dishevelled 1 and 2 in Normal Cardiac Outflow Tract, Cochlea, and Neural Tube Development

(2008) S. Leah Etheridge et al.   PLoS Genetics