Evolutionarily conservedTbx5–Wnt2/2bpathway orchestrates cardiopulmonary development

Specialized impulse conduction pathway in the alligator heart

(2018) Bjarke Jensen et al.   eLife

Complex Interdependence Regulates Heterotypic Transcription Factor Distribution and Coordinates Cardiogenesis

(2016) Luis Luna-Zurita et al.   CELL

The Cardiac TBX5 Interactome Reveals a Chromatin Remodeling Network Essential for Cardiac Septation

(2016) Lauren Waldron et al.   DEVELOPMENTAL CELL

Development of the atrial septum in relation to postnatal anatomy and interatrial communications

(2016) Bjarke Jensen et al.   HEART

Cilia gene mutations cause atrioventricular septal defects by multiple mechanisms

(2016) Ozanna Burnicka-Turek et al.   HUMAN MOLECULAR GENETICS

Pitx2 modulates a Tbx5 -dependent gene regulatory network to maintain atrial rhythm

(2016) Rangarajan D. Nadadur et al.   Science Translational Medicine

Molecular developmental mechanism in polypterid fish provides insight into the origin of vertebrate lungs

(2016) Norifumi Tatsumi et al.   Scientific Reports

A Retinoic Acid-Hedgehog Cascade Coordinates Mesoderm-Inducing Signals and Endoderm Competence during Lung Specification

(2016) Scott A. Rankin et al.   Cell Reports

The pulmonary mesenchyme directs lung development

(2015) David McCulley et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank

(2015) Louise V Wain et al.   Lancet Respiratory Medicine

Lung development: orchestrating the generation and regeneration of a complex organ

(2014) M. Herriges et al.   DEVELOPMENT

A Molecular atlas ofXenopusrespiratory system development

(2014) Scott A. Rankin et al.   DEVELOPMENTAL DYNAMICS

Long noncoding RNAs are spatially correlated with transcription factors and regulate lung development

(2014) M. J. Herriges et al.   GENES & DEVELOPMENT

Gene Regulatory Networks Governing Lung Specification

(2014) Scott A. Rankin et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Xenbase, the Xenopus model organism database; new virtualized system, data types and genomes

(2014) J. Brad Karpinka et al.   NUCLEIC ACIDS RESEARCH

Foxf Genes Integrate Tbx5 and Hedgehog Pathways in the Second Heart Field for Cardiac Septation

(2014) Andrew D. Hoffmann et al.   PLoS Genetics

DNA-Binding Specificities of Human Transcription Factors

(2013) Arttu Jolma et al.   CELL

Zebrafishtbx5paralogs demonstrate independent essential requirements in cardiac and pectoral fin development

(2013) Lindsay E. Parrie et al.   DEVELOPMENTAL DYNAMICS

Expression of a lung developmental cassette in the adult and developing zebrafish swimbladder

(2013) Amanda N. Cass et al.   EVOLUTION & DEVELOPMENT

Coordination of heart and lung co-development by a multipotent cardiopulmonary progenitor

(2013) Tien Peng et al.   NATURE

Evolution and development of the building plan of the vertebrate heart

(2012) Bjarke Jensen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Tbx5-Hedgehog Molecular Networks Are Essential in the Second Heart Field for Atrial Septation

(2012) Linglin Xie et al.   DEVELOPMENTAL CELL

Regulatory variation in a TBX5 enhancer leads to isolated congenital heart disease

(2012) Scott Smemo et al.   HUMAN MOLECULAR GENETICS

TBX5 drives Scn5a expression to regulate cardiac conduction system function

(2012) David E. Arnolds et al.   JOURNAL OF CLINICAL INVESTIGATION

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Identifying ChIP-seq enrichment using MACS

(2012) Jianxing Feng et al.   Nature Protocols

Identifying the Evolutionary Building Blocks of the Cardiac Conduction System

(2012) Bjarke Jensen et al.   PLoS One

Multiple Roles and Interactions of Tbx4 and Tbx5 in Development of the Respiratory System

(2012) Ripla Arora et al.   PLoS Genetics

Stage-Specific Optimization of Activin/Nodal and BMP Signaling Promotes Cardiac Differentiation of Mouse and Human Pluripotent Stem Cell Lines

(2011) Steven J. Kattman et al.   Cell Stem Cell

Signaling through BMP receptors promotes respiratory identity in the foregut via repression of Sox2

(2011) E. T. Domyan et al.   DEVELOPMENT

Interplay between Wnt2 and Wnt2bb controls multiple steps of early foregut-derived organ development

(2011) Morgane Poulain et al.   DEVELOPMENT

A revised model of Xenopus dorsal midline development: Differential and separable requirements for Notch and Shh signaling

(2011) Sara M. Peyrot et al.   DEVELOPMENTAL BIOLOGY

Wnt Signaling Is Required for Early Development of Zebrafish Swimbladder

(2011) Ao Yin et al.   PLoS One

Comparative Transcriptome Analyses Indicate Molecular Homology of Zebrafish Swimbladder and Mammalian Lung

(2011) Weiling Zheng et al.   PLoS One

Co-occupancy by multiple cardiac transcription factors identifies transcriptional enhancers active in heart

(2011) A. He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inducible Cassette Exchange: A Rapid and Efficient System Enabling Conditional Gene Expression in Embryonic Stem and Primary Cells

(2011) Michelina Iacovino et al.   STEM CELLS

sonic hedgehog is required in pulmonary endoderm for atrial septation

(2009) A. D. Hoffmann et al.   DEVELOPMENT

Development of zebrafish swimbladder: The requirement of Hedgehog signaling in specification and organization of the three tissue layers

(2009) Cecilia Lanny Winata et al.   DEVELOPMENTAL BIOLOGY

Wnt2/2b and β-Catenin Signaling Are Necessary and Sufficient to Specify Lung Progenitors in the Foregut

(2009) Ashley M. Goss et al.   DEVELOPMENTAL CELL

Reptilian heart development and the molecular basis of cardiac chamber evolution

(2009) Kazuko Koshiba-Takeuchi et al.   NATURE

Xenbase: gene expression and improved integration

(2009) Jeff B. Bowes et al.   NUCLEIC ACIDS RESEARCH

 -Catenin promotes respiratory progenitor identity in mouse foregut

(2009) K. S. Harris-Johnson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Gata6-Wnt pathway required for epithelial stem cell development and airway regeneration

(2008) Yuzhen Zhang et al.   NATURE GENETICS

Tbx5-dependent pathway regulating diastolic function in congenital heart disease

(2008) Y. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY